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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 9 of 9. This is the beginning of the thread.
Posted by Marty on July 20, 2008, at 0:48:25
There's a guy on the web saying he had a couple weeks of depersonalisation after a serotoniin syndrome induced by taking 5mg of 5-HTP (supplement) with Tianeptine (which I assume is the fit-all 12.5mg TID) ............As I seriously think my next move (not feeling well.. waiting to see if Wellbutrin restart will reboot Tianeptine initial effect) I'm looking forward to try Tianeptine with a serotonergic agent but I'm afraid of the reaction I could have.
Any thoughts about this would be appreciated. What would you suggest ?
/\/\arty
Posted by Sigismund on July 20, 2008, at 3:45:18
In reply to *SSRI + Tianeptine = Possible Serotonin Syndrome ?, posted by Marty on July 20, 2008, at 0:48:25
I have taken with tianeptine
SAMe.........OK
Deprenyl.........not so good
Parnate.........awful
5htp.........OK, although I'm not sure that I remember. Nothing awful.
Posted by Quintal on July 20, 2008, at 8:31:55
In reply to *SSRI + Tianeptine = Possible Serotonin Syndrome ?, posted by Marty on July 20, 2008, at 0:48:25
I took it with Lexapro and it wasn't very nice. That might have just been the Lexaro though.
Q
Posted by Marty on July 20, 2008, at 8:40:26
In reply to Re: *SSRI + Tianeptine = Possible Serotonin Syndrome ?, posted by Sigismund on July 20, 2008, at 3:45:18
> I have taken with tianeptine
> SAMe.........OK
> Deprenyl.........not so good
> Parnate.........awful
> 5htp.........OK, although I'm not sure that I remember. Nothing awful.
---
Okay.. this is reassuring me. Thanks/\/\arty
Posted by Marty on July 20, 2008, at 8:45:02
In reply to Re: *SSRI + Tianeptine = Possible Serotonin Syndro, posted by Quintal on July 20, 2008, at 8:31:55
> I took it with Lexapro and it wasn't very nice. That might have just been the Lexaro though.
---
Intersting... could you describe how it was like ? .. What was the difference between your response (or non response) on Lexapro+Tianeptine and the other SSRI trial you did in the past ? Also did you feel Tianeptine somehow was reducing the usual SSRI side effects ? last question: What's your diagnostic/symptoms ?I know I ask you alot of question and maybe you don't have the time or the motivation to answer me those, but not many people can answer those and if I add an SSRI to Tianeptine it will be Lexapro as I already have some. So your answers has value for me.
Thanks,
/\/\arty
Posted by Quintal on July 20, 2008, at 16:58:51
In reply to Re: *SSRI + Tianeptine = Possible Serotonin Syndro » Quintal, posted by Marty on July 20, 2008, at 8:45:02
>Intersting... could you describe how it was like ?
I felt cold and shivery. I don't know if that had anything to do with some sort of serotonin problem, but I felt pretty much like that on Lexapro (amd other SSRIs) alone.
>What was the difference between your response (or non response) on Lexapro+Tianeptine and the other SSRI trial you did in the past ?
I only took it for one day. I felt so awful I just dropped the Lexapro and went back to tianeptine.
>Also did you feel Tianeptine somehow was reducing the usual SSRI side effects ?
Not really, I still had all the classic SSRI side effects. I don't think it would be that effective because it's not a serotonin blocker like cyproheptadine or something like that.
>last question: What's your diagnostic/symptoms ?
Bipolar I with psychotic features, social anxiety and agoraphobia.
>I know I ask you alot of question and maybe you don't have the time or the motivation to answer me those, but not many people can answer those and if I add an SSRI to Tianeptine it will be Lexapro as I already have some. So your answers has value for me.
No problem! There are some posts in the archives of what I reported at the time if that would be useful to you.
Q
Posted by Marty on July 20, 2008, at 17:01:18
In reply to Re: *SSRI + Tianeptine = Possible Serotonin Syndro » Marty, posted by Quintal on July 20, 2008, at 16:58:51
Hi,
> No problem! There are some posts in the archives of what I reported at the time if that would be useful to you.
>
> QThanks for all Quintal !
/\/\arty
Posted by Crotale on July 20, 2008, at 22:23:47
In reply to *SSRI + Tianeptine = Possible Serotonin Syndrome ?, posted by Marty on July 20, 2008, at 0:48:25
What about MAOIs - anyone know if it's safe to use serotonin transporter agonists like tianeptine with them?
-Crotale
Posted by Marty on July 20, 2008, at 23:24:17
In reply to Re: *SSRI + Tianeptine = Possible Serotonin Syndro, posted by Crotale on July 20, 2008, at 22:23:47
> What about MAOIs - anyone know if it's safe to use serotonin transporter agonists like tianeptine with them?
---
Hi Crotale. Unlikely to be recommended; In fact it's specified that you should not mix both. That said, just for your information there's no such thing as 'Transporter Agonist'. In the case of Tianeptine you can say Serotonin Transporter Reuptake ENHANCER or less commonly used term ACCELERATOR./\/\arty
This is the end of the thread.
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