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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 17 of 17. This is the beginning of the thread.
Posted by linkadge on June 22, 2007, at 13:18:55
An additional (new) study demonstrates the AD effect of scopolamine in unipolar or bipolar depression.
http://www.clinicalpsychiatrynews.com/article/PIIS0270664407703417/fulltext
Linkadge
Posted by Phillipa on June 22, 2007, at 13:26:23
In reply to newer study on scopolamine for depression, posted by linkadge on June 22, 2007, at 13:18:55
Link that's IV in already depressed or bipolar patients what happens to those who use the patch for seasickness do they get a lift in mood or just not get seasick? Love Phillipa
Posted by kaleidoscope on June 22, 2007, at 14:03:34
In reply to newer study on scopolamine for depression, posted by linkadge on June 22, 2007, at 13:18:55
>Scopolamine.....depression...
Perhaps the patients forgot they were depressed?!
Posted by Quintal on June 22, 2007, at 15:15:07
In reply to newer study on scopolamine for depression, posted by linkadge on June 22, 2007, at 13:18:55
I remember liking the effect it had, particularly combined with Solpodeine Max. I'm going to buy a packet at the chemists tomorrow and see what it does this time.
Q
Posted by rovers95 on June 23, 2007, at 23:31:02
In reply to Re: newer study on scopolamine for depression, posted by Quintal on June 22, 2007, at 15:15:07
> I remember liking the effect it had, particularly combined with Solpodeine Max. I'm going to buy a packet at the chemists tomorrow and see what it does this time.
>
> QWots the product to buy from the chemists called???
regards
rover
Posted by chiron on June 24, 2007, at 10:56:55
In reply to Re: newer study on scopolamine for depression » linkadge, posted by Phillipa on June 22, 2007, at 13:26:23
do they know how it works...neurotransmitters?
it's good to hear of new options = hope for the tx resistant.
Posted by linkadge on June 24, 2007, at 12:34:53
In reply to Re: newer study on scopolamine for depression, posted by chiron on June 24, 2007, at 10:56:55
It blocks cholinergic muscarinic receptors. Blocking these receptors can increase dopamine in the neucleus accumbens, and hence the minor/moderat abuse potential of anticholinergics.
Anticholinergics can make you a bit forgetfull. They can also make you feel a bit stoned, detached, sometimes psychotic.
My scopolamine trial was a good one. I would continue with it on a daily basis if it was available and affordable.
Basically, it made me feel very much in the present. It stopped a chattering mind. It made many things seem very interesting. It also created a pleasant sence of otherworldliness. Like I had jumped out of this chaotic callostrophobic world and jumped into a more personal zone where things were more interesting, more plyable and less riged and strict.
I had used a similar drug called cogenitn. Cogentin is offically used for parkinsons or AP induced akathesia, but it is also an anticholinergic with similar effects.
It too, brigtened things up. Made things feel less regimented, and made my problems feel more subjective.
Linkadge
Posted by rovers95 on June 24, 2007, at 13:46:56
In reply to Re: newer study on scopolamine for depression, posted by Quintal on June 22, 2007, at 15:15:07
> I remember liking the effect it had, particularly combined with Solpodeine Max. I'm going to buy a packet at the chemists tomorrow and see what it does this time.
>
> QWhat is the packet you can buy at the chemists i meant????? can u get scopolamine over prescription and can it be used regularaly??? Also would the dopaminergenic effects render it to be pro-sexual???
rover
regards
Posted by polarbear206 on June 25, 2007, at 9:24:29
In reply to Re: newer study on scopolamine for depression, posted by linkadge on June 24, 2007, at 12:34:53
> It blocks cholinergic muscarinic receptors. Blocking these receptors can increase dopamine in the neucleus accumbens, and hence the minor/moderat abuse potential of anticholinergics.
>
> Anticholinergics can make you a bit forgetfull. They can also make you feel a bit stoned, detached, sometimes psychotic.
>
> My scopolamine trial was a good one. I would continue with it on a daily basis if it was available and affordable.
>
> Basically, it made me feel very much in the present. It stopped a chattering mind. It made many things seem very interesting. It also created a pleasant sence of otherworldliness. Like I had jumped out of this chaotic callostrophobic world and jumped into a more personal zone where things were more interesting, more plyable and less riged and strict.
>
> I had used a similar drug called cogenitn. Cogentin is offically used for parkinsons or AP induced akathesia, but it is also an anticholinergic with similar effects.
>
> It too, brigtened things up. Made things feel less regimented, and made my problems feel more subjective.
>
> Linkadge
>
>
>
Link,Something you might be interested in knowing. My good friend has major depression and she was put on Mirapex for RLS she developed. She was able to go off her antidepressants ( Pamelor/celexa combo) this past spring when she noticed it improved her depression. She has been in remission to this day. You might of already tried this, if not I would strongly consider. There is info out there about people who used it for RLS who noticed mood elevation as a positive and welcomed side effect.
Polarbear
>
>
>
>
Posted by linkadge on June 25, 2007, at 15:53:46
In reply to Re: newer study on scopolamine for depression, posted by polarbear206 on June 25, 2007, at 9:24:29
Well, thats the bottom line. Just because something is not classified as an antidepressant does not mean it can not act this way.
Linkadge
Posted by Iansf on June 25, 2007, at 16:57:16
In reply to Re: newer study on scopolamine for depression, posted by linkadge on June 24, 2007, at 12:34:53
> My scopolamine trial was a good one. I would continue with it on a daily basis if it was available and affordable.
> Linkadge
>
In pill form, it's not nearly so expensive as the patches. One source I found very quickly had 100 tabs of 0.4mg for $39. The cheapest I found for the patch was $33 for four patches of 1.5mg each. Is there a significant difference in using the pill vs. the patch?
John
Posted by polarbear206 on June 25, 2007, at 19:37:31
In reply to Re: newer study on scopolamine for depression, posted by linkadge on June 25, 2007, at 15:53:46
> Well, thats the bottom line. Just because something is not classified as an antidepressant does not mean it can not act this way.
>
> Linkadge
Of course this is true, happens all the time, never disagreed.You never answered my question, have your considered this or am I the first to tell you about this.
Just trying to help.
Posted by linkadge on June 25, 2007, at 20:22:28
In reply to Re: newer study on scopolamine for depression » linkadge, posted by polarbear206 on June 25, 2007, at 19:37:31
Sorry I didn't know you had asked as question. What was your question ?
Linkadge
Posted by polarbear206 on June 25, 2007, at 22:14:20
In reply to Re: newer study on scopolamine for depression » polarbear206, posted by linkadge on June 25, 2007, at 20:22:28
> Sorry I didn't know you had asked as question. What was your question ?
>
> Linkadge
Just wanted to know if you have looked into trying mirapex for your hard to treat depression?
Posted by linkadge on June 26, 2007, at 8:13:37
In reply to Re: newer study on scopolamine for depression » linkadge, posted by polarbear206 on June 25, 2007, at 22:14:20
Sure, I've looked into a lot of things. Unfortunately one needs to have a doctor that is openminded to such treatments.
Doctors around here generally tell you what you are to take.
Meds are usually an SSRI and an antipsychotic of some sort. If low doses don't work, one is raised to mind numbing doses.
That is pretty much where you are told that you need to wait half a year for your meds to kick in, and that no adjuments of doses will be made during this time.
This is generally where I stop seeing doctors.
Linkadge
Posted by polarbear206 on June 26, 2007, at 11:01:02
In reply to Re: newer study on scopolamine for depression, posted by linkadge on June 26, 2007, at 8:13:37
> Sure, I've looked into a lot of things. Unfortunately one needs to have a doctor that is openminded to such treatments.
>
> Doctors around here generally tell you what you are to take.
>
> Meds are usually an SSRI and an antipsychotic of some sort. If low doses don't work, one is raised to mind numbing doses.
>
> That is pretty much where you are told that you need to wait half a year for your meds to kick in, and that no adjuments of doses will be made during this time.
>
> This is generally where I stop seeing doctors.
>
>
>
> Linkadge
There are ways to get around it. Just go to you PCP and tell him you have RLS and it is interfering with you getting a good nights sleep.Polarbear
Posted by rovers95 on June 28, 2007, at 17:42:02
In reply to Re: newer study on scopolamine for depression » linkadge, posted by polarbear206 on June 26, 2007, at 11:01:02
Iv tried the Kwells over the last few todays.........did very little - back to the ket me thinks!!!
rover
This is the end of the thread.
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