Psycho-Babble Medication Thread 760318

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Re: Advice from Parnate users please..Malcolm

Posted by malcolm664 on May 31, 2007, at 23:03:59

In reply to Re: Advice from Parnate users please..Malcolm, posted by sophia04 on May 31, 2007, at 20:50:30

> Thank you Malcolm,
>
> How long have you been taking parnate? How long have you been on 60mg? Has it taken you a relatively long time to reach that dose? I too am on 60mg and have been for a couple weeks. Wondering IF i will have a breakthough.
>
> Thanks,
> Sophia

I've been on Parnate since around 23rd of April but first really noticed the effect a couple of days ago. I've been keeping a detailed diary but unfortunately, I didn't write down how much I started with (I THINK 30 mgs, so apparently my diary isn't detailed enough) but doubled the dose (to 60 mgs) about a week ago and that's when I noticed the difference. I see my doc tomorrow and will ask him if he can tell me what I started out with and when exactly I moved it up (again, I THINK it was about a week ago).

I remember calling him to tell him that I wasn't really feeling better at the dose that I was on, so that's when he had me increase it...to 60 mgs. That much I know is accurate.

In fact, just this evening I was talking with my brother and telling him how I thought that the med was finally working. I defintitely feel much...calmer...that's the only way to describe it. And the anxiety up to this point was pretty crushing.

I can only hope and wish that you experience a similar reaction, but with all psych med, reactions are notoriously individual.

I'd say "hang in there", but I know that phrases like that are meaningless when people say things like that to me.

What I will say is that I know exactly what you're going through, so if that's any comfort...Of course, I'm being a bit presumptuous by comparing our situations. For all I know yours could be much, much worse than mine.

BTW, I'm also on 1 mg xanax XR (taken when I wake up) and .75 mgs of Klonopin (taken right before bedtime).

I'll let you know what I find out from my doc after our appointment tomorrow and post a follow-up message to this BB...or you can also e-mail me at msaldanha@verizon.net.

Malcolm

 

Re: Advice from Parnate users please..Malcolm

Posted by malcolm664 on June 1, 2007, at 19:44:31

In reply to Re: Advice from Parnate users please..Malcolm, posted by malcolm664 on May 31, 2007, at 23:03:59

> > Thank you Malcolm,
> >
> > How long have you been taking parnate? How long have you been on 60mg? Has it taken you a relatively long time to reach that dose? I too am on 60mg and have been for a couple weeks. Wondering IF i will have a breakthough.
> >
> > Thanks,
> > Sophia
>
> I've been on Parnate since around 23rd of April but first really noticed the effect a couple of days ago. I've been keeping a detailed diary but unfortunately, I didn't write down how much I started with (I THINK 30 mgs, so apparently my diary isn't detailed enough) but doubled the dose (to 60 mgs) about a week ago and that's when I noticed the difference. I see my doc tomorrow and will ask him if he can tell me what I started out with and when exactly I moved it up (again, I THINK it was about a week ago).
>
> I remember calling him to tell him that I wasn't really feeling better at the dose that I was on, so that's when he had me increase it...to 60 mgs. That much I know is accurate.
>
> In fact, just this evening I was talking with my brother and telling him how I thought that the med was finally working. I defintitely feel much...calmer...that's the only way to describe it. And the anxiety up to this point was pretty crushing.
>
> I can only hope and wish that you experience a similar reaction, but with all psych med, reactions are notoriously individual.
>
> I'd say "hang in there", but I know that phrases like that are meaningless when people say things like that to me.
>
> What I will say is that I know exactly what you're going through, so if that's any comfort...Of course, I'm being a bit presumptuous by comparing our situations. For all I know yours could be much, much worse than mine.
>
> BTW, I'm also on 1 mg xanax XR (taken when I wake up) and .75 mgs of Klonopin (taken right before bedtime).
>
> I'll let you know what I find out from my doc after our appointment tomorrow and post a follow-up message to this BB...or you can also e-mail me at msaldanha@verizon.net.
>
> Malcolm
>
>

Well, I saw my doc today. He definitely doesn't think that it's a fluke that I'm feeling better: it's definitely due to the Parnate. So for now, he's got me at 60 mgs (until I see him again in 2 weeks). He also told me to stop taking the Xanax altogether and prescribed Ambien to help with the sleep. He said that Ambien (unlike other sleep meds) clears your system in the mornings, so there's no residual drowsiness the next day.

As far as dosages, I stared on 30, went up to 40 then slowly up to 60 mgs (of the Parnate, that is).

He's also more hopeful that the Parnate will last long-term. He said that what happened with the Nardil a year ago (I was seeing another doc for meds at the time) was that I experienced such a hypermanic over-reaction that there was no way it could be sustained. But given (at least so far) that I haven't lapsed into euphoria, the chances that the med will continue to work are very good.

Of course, even with a doc as experienced as he is, he can't guarantee me anything. But as of today, I'm much more hopeful about my future (and immediately about the internship which I start a week from this Monday than I was a week ago).

So for everyone who took the time to respond over the last several weeks to my incessant med-related questions (many of them probably repetitive), I just want to say: Thanks!!

I'll still keep posting here and if anyone has any questions, please feel free to e-mail me: msaldanha@verizon.net. Just put "Psyhobabble question" in the subject line so I don't confuse it with spam. That way I know that it's another poster from this bulletin board and I'll try and respond as quickly as I can.

I wish everyone the best and I of all people of course know very well what everyone is or has gone through.

Regards-
Malcolm

 

Re: Parnate users dose time/provigil..Malcolm

Posted by sophia04 on June 1, 2007, at 20:45:30

In reply to Re: Advice from Parnate users please..Malcolm, posted by malcolm664 on June 1, 2007, at 19:44:31

Malcom, + friends

That's great news!! I had the best day today that I have had in weeks - presumably, I think, because I got more than 3 hours of sleep. I have essentially been getting NO sleep despite the fact that I've dabbled w/ Lunesta, Lorazepam + Benadryl. I didn't work today and was able to sleep until noon -despite the fact that it took til 3:00 am on 1.5mg of lorazepam.

Also, my doc is in France til mid June and has never prescribed Parnate before. I'm getting all of my education right here on psycho-babble (thank you!). I think I want to start taking the bulk of the meds early in the day and try provigil and hopefully won't need a sleep aid. What do you think?

thanks again,

Sophia

 

Re: Advice from Parnate users please..football

Posted by sophia04 on June 1, 2007, at 20:49:54

In reply to Re: Advice from Parnate users please.., posted by F00TBALL on May 30, 2007, at 1:43:42

Has anyone tried to take the bulk of their parnate early, say by 2:00 pm + provigil to avoid the insomnia and forgo the sleep aid?

Thanks,
Sophia

 

Re: Advice from Parnate users please..football

Posted by malcolm664 on June 1, 2007, at 23:15:36

In reply to Re: Advice from Parnate users please..football, posted by sophia04 on June 1, 2007, at 20:49:54

> Has anyone tried to take the bulk of their parnate early, say by 2:00 pm + provigil to avoid the insomnia and forgo the sleep aid?
>
> Thanks,
> Sophia

I started out taking the Parnate in divided does, the first when I woke up and then the second dose around mid-day, but the exhaustion really got to me. So what Dr. Vittone suggested I do was to take divided doses in the evening, say 30 mgs around 6 pm and then the final 30 mgs right before bed. I was skeptical, b/c of the insomnia, but slowly it's becoming less and less of a problem.

So I've given up the Xanax XR although for now am still taking .75 mgs of the Klonopin, plus the Ambien. It's about 12 midnight right now and I'm about to hit the sack.

I'll post another message tomorrow about my sleep.

Malcolm

BTW, I asked him again about prescribing Provigil and he says that there's anecdotal evidence that combining stimulants with MAOI's is dangerous. I still think that he's over-reacting, but he's the doc and I sure as hell can't write myself a script for Provigil myself. And he seems to be a really competent physician, so I don't think that I ought to do anything against his wishes.

Malcolm

 

Re: Advice from Parnate users please..football

Posted by malcolm664 on June 2, 2007, at 11:58:40

In reply to Re: Advice from Parnate users please..football, posted by malcolm664 on June 1, 2007, at 23:15:36

> > Has anyone tried to take the bulk of their parnate early, say by 2:00 pm + provigil to avoid the insomnia and forgo the sleep aid?
> >
> > Thanks,
> > Sophia
>
> I started out taking the Parnate in divided does, the first when I woke up and then the second dose around mid-day, but the exhaustion really got to me. So what Dr. Vittone suggested I do was to take divided doses in the evening, say 30 mgs around 6 pm and then the final 30 mgs right before bed. I was skeptical, b/c of the insomnia, but slowly it's becoming less and less of a problem.
>
> So I've given up the Xanax XR although for now am still taking .75 mgs of the Klonopin, plus the Ambien. It's about 12 midnight right now and I'm about to hit the sack.
>
> I'll post another message tomorrow about my sleep.
>
> Malcolm
>
> BTW, I asked him again about prescribing Provigil and he says that there's anecdotal evidence that combining stimulants with MAOI's is dangerous. I still think that he's over-reacting, but he's the doc and I sure as hell can't write myself a script for Provigil myself. And he seems to be a really competent physician, so I don't think that I ought to do anything against his wishes.
>
> Malcolm
>
>

Well it's close to 1 pm on Sun afternoon and I woke up about a hour ago, so I'd say that I slept really great (in fact, too well); I initially woke up at around 8:30 am, but then fell right back to sleep; so the Ambien must be working.

I'm taking 12.5 mgs.

And I had no problems actually falling asleep. Of course, it's only one night, but I think I'll try breaking the pill in half tonight and see what happens. It could also be that I've been so deprived of a really great night's sleep ever since starting the Parnate, that the Ambien just allowed me to just catch up.

I just hope that waking up in the AM will not be a problem in the future while on Ambien. Nothing's worse than getting to work late.

Either way, it feels great!

best-
Malcolm

 

Re: Advice from Parnate users please..football » sophia04

Posted by OzLand on June 7, 2007, at 19:32:48

In reply to Re: Advice from Parnate users please..football, posted by sophia04 on June 1, 2007, at 20:49:54

I take 20 mg. of Parnate in the morning and am at the point of taking 10 mg. at noon and/or before 2 p.m. I am alternating now with taking 20 mg. at noon with 10 mg. everyother day. I can't take it after that time of the day or I will be up all night. I have Seroquel to take at night too if needed, but I would rather not, and this is why I take all of my Parnate before 2 p.m.

 

Re: Advice from Parnate users please..

Posted by sophia04 on June 8, 2007, at 2:31:10

In reply to Re: Advice from Parnate users please..football, posted by malcolm664 on June 1, 2007, at 23:15:36

I just don't think I can take Parnate anymore. It's been 9 weeks now - almost 3 on 60 mgs and I still am skeptical of any antidepressant effect. I'm drinking too much coffee - despite the fact that I haven't touched it for 10 years because of anxiety - but I'm so wasted from the resulting insomnia (ativan is working ok) and daytime fatigue. My dizzy/near fainting spells are periodically returning. I really don't want to "throw the baby out with the bathwater" because I feel like I've just endured 9 weeks of hell, but I think I need to accept that Parnate - the "gold standard" - is just another bust for this treatment-resistant gal. Any thoughts?

Sophia

 

Re: Advice from Parnate users please.. » sophia04

Posted by OzLand on June 11, 2007, at 22:29:41

In reply to Re: Advice from Parnate users please.., posted by sophia04 on June 8, 2007, at 2:31:10

I don't know what to say for sure. Sometimes it takes longer to work. Years ago it took at least a month or more to really start working for me. I took Mellaril at night for sleep, not something advisable anymore. Now I have a low dose of Seroquel if I need it for sleep. I am now at 40 mg., and I don't want to go higher. I think my therapy with my new therapist will help more than increasing the Parnate. I have not found any other antidepressant that works, and against my better judgment I did ECT. It helped me be less depressed before I quit doing it because of noting bad side effects and memory problems. I paid a price for doing ECT, and so I am not happy about that. Try giving the Parnate more time. Maybe you are on too much, and you were not given enough time to see if it would start to work at a lower dose. I would wonder. Doctors like to up things after a couple of weeks, and then up them again after another few weeks, etc. Maybe it is time to see if it will work by not continuing to up it?????

 

Re: Advice from Parnate users please..

Posted by Honore on June 12, 2007, at 0:31:31

In reply to Re: Advice from Parnate users please.. » sophia04, posted by OzLand on June 11, 2007, at 22:29:41

I had terrible daytime sleepiness on parnate-- which sounds contradictory, but I've found from reading here that it's not totally unknown either. Others have reported that response.

I kept taking it for several years, until another factor forced me to stop== because it helped with the depression, even though I was semi-conscious for large periods of the day, every day. I also tended to need to sleep frequently-- I literally couldn't stay awake.

But I'm glad to be off-- I think MAOIs are the only ADs that work for me, and Emsam doesn't have the same sleep effects.

Honore

 

Re: Advice from Parnate users please.. » sophia04

Posted by malcolm664 on June 12, 2007, at 4:58:44

In reply to Re: Advice from Parnate users please.., posted by sophia04 on June 8, 2007, at 2:31:10

Well I wish I knew what to say; I started taking it towards the end of April and first noticed the AD effects about two weeks ago, so I would think that you should be feeling something by now.

And I'm also on 60 mgs. Do you supplement with Klonopin or Xanax XR? I'm not saying that that would definitely help, but that's what I've been doing since I started the Parnate and perhaps it's the combination that helps.

It's obviously time for you to re-evaluate the Parnate with your pdoc, if you haven't done so already.

Best-
Malcolm

> I just don't think I can take Parnate anymore. It's been 9 weeks now - almost 3 on 60 mgs and I still am skeptical of any antidepressant effect. I'm drinking too much coffee - despite the fact that I haven't touched it for 10 years because of anxiety - but I'm so wasted from the resulting insomnia (ativan is working ok) and daytime fatigue. My dizzy/near fainting spells are periodically returning. I really don't want to "throw the baby out with the bathwater" because I feel like I've just endured 9 weeks of hell, but I think I need to accept that Parnate - the "gold standard" - is just another bust for this treatment-resistant gal. Any thoughts?
>
> Sophia

 

Re: Advice from Parnate users please..

Posted by sophia04 on June 13, 2007, at 0:38:00

In reply to Re: Advice from Parnate users please.. » sophia04, posted by malcolm664 on June 12, 2007, at 4:58:44

Thanks Malcom,
I did have an appointment finally w/ my doc and we decided to adjust the dose time - the daytime fatigue is so impactful to my work schedule and quality of life. I'm currently taking 30mg at 7:00pm and the other 30 mg at 10:00. I also (just last night) started taking 25 mg of Seroquel. Would you believe I still had insomnia and had to take ativan during the night on top of that?! Parnate's remedy-resistant insomnia is totally surreal. We shall see what happens tonight.
I'll continue to keep you all posted. Thanks!!

 

Re: Advice from Parnate users please.. » sophia04

Posted by malcolm664 on June 13, 2007, at 20:07:36

In reply to Re: Advice from Parnate users please.., posted by sophia04 on June 13, 2007, at 0:38:00

> Thanks Malcom,
> I did have an appointment finally w/ my doc and we decided to adjust the dose time - the daytime fatigue is so impactful to my work schedule and quality of life. I'm currently taking 30mg at 7:00pm and the other 30 mg at 10:00. I also (just last night) started taking 25 mg of Seroquel. Would you believe I still had insomnia and had to take ativan during the night on top of that?! Parnate's remedy-resistant insomnia is totally surreal. We shall see what happens tonight.
> I'll continue to keep you all posted. Thanks!!
>

What's Seroquel like? I've asked my doc about prescribing that and so far he has resisted. What he said is that Seroquel would only make the daytime drowsiness worse. Does it have any effects beyond just a sleep aid (i.e., does it help with anxiety or depression?).

Malcolm

 

Re: Advice from Parnate users please.. » malcolm664

Posted by malcolm664 on June 13, 2007, at 20:09:58

In reply to Re: Advice from Parnate users please.. » sophia04, posted by malcolm664 on June 13, 2007, at 20:07:36

> > Thanks Malcom,
> > I did have an appointment finally w/ my doc and we decided to adjust the dose time - the daytime fatigue is so impactful to my work schedule and quality of life. I'm currently taking 30mg at 7:00pm and the other 30 mg at 10:00. I also (just last night) started taking 25 mg of Seroquel. Would you believe I still had insomnia and had to take ativan during the night on top of that?! Parnate's remedy-resistant insomnia is totally surreal. We shall see what happens tonight.
> > I'll continue to keep you all posted. Thanks!!
> >
>
> What's Seroquel like? I've asked my doc about prescribing that and so far he has resisted. What he said is that Seroquel would only make the daytime drowsiness worse. Does it have any effects beyond just a sleep aid (i.e., does it help with anxiety or depression?).
>
> Malcolm

Oops, I didn't notice that you had just started the Seroquel (which probably means that it's too soon for you to know whether it will help with anxiety or depression). But did it help you sleep?

 

Re: Advice from Parnate users please..

Posted by sophia04 on June 14, 2007, at 0:23:50

In reply to Re: Advice from Parnate users please.. » malcolm664, posted by malcolm664 on June 13, 2007, at 20:09:58

The first two nights I took Seroquel I got about 3 hours of uninterupted sleep. Docs wants me to go from 25mg to 50mg tonight. I was kind of groggy and did awake at 3;00 am w/ a banging headache, but feel a heck of a lot better than I did when I took the Parnate throughout the daytime. I also took a Provigil today because my doc gave me a few samples and I wanted to try it out - best day I've had in 10 weeks energy and mood-wise. Could it be the provigil? seroquel? parnate? So many variables at this point. I'll keep you posted though.

 

Re: Advice from Parnate (insomnia) users please..

Posted by sophia04 on June 14, 2007, at 19:09:48

In reply to Re: Advice from Parnate users please.., posted by sophia04 on June 14, 2007, at 0:23:50

LAst night I increased my Seroquel 50 mg and hardly got ANY sleep. This is crazy i know. I woke up after about an hour and struggled the rest of the night until I finally took lorazepam. My doc said this response is untypical, but I will go back down to 25mg for one more night before I move on to Ambien... i guess. I also feel pretty yucky today - naussea, hang-over, etc. My doc also tells me that she thinks the parnate induced insomnia will actually go away, or at least decrease. Has this been the case for ANYone out there?? Are there any long time users, who take the bulk of the parnate at night, use no sleep aids??

 

Re: Advice from Parnate (insomnia) users please.. » sophia04

Posted by psychobot5000 on June 15, 2007, at 8:03:48

In reply to Re: Advice from Parnate (insomnia) users please.., posted by sophia04 on June 14, 2007, at 19:09:48

> LAst night I increased my Seroquel 50 mg and hardly got ANY sleep. This is crazy i know. I woke up after about an hour and struggled the rest of the night until I finally took lorazepam. My doc said this response is untypical, but I will go back down to 25mg for one more night before I move on to Ambien... i guess. I also feel pretty yucky today - naussea, hang-over, etc. My doc also tells me that she thinks the parnate induced insomnia will actually go away, or at least decrease. Has this been the case for ANYone out there?? Are there any long time users, who take the bulk of the parnate at night, use no sleep aids??
________________

Okay, so Parnate-induced insomnia is not at all uncommon, though I believe you mentioned you were taking Provigil/modafinil, and that caused me insomnia when I took it, also. Parnate or other MAOi-induced insomnia does have the reputation of going away after a period of time weeks or months, usually. Maybe not completely, but significantly. Sleep is a problem on MAOis for some.

Do you find that the Parnate causes drowsy periods during the day? Sometimes you can time the dosing so that the drowsiness hits you at bedtime, or, failing that, you can try taking the entire dose as far away from bedtime as possible--though I don't think you're supposed to take it all at once.

Since MAOi-induced insomnia can sometimes be a serious problem, some users do have to take sleep aids all the time, it's true.

Hope you find something that works it out.

 

Re: Advice from Parnate (insomnia) bye bye Parnate

Posted by sophia04 on June 16, 2007, at 22:31:33

In reply to Re: Advice from Parnate (insomnia) users please.. » sophia04, posted by psychobot5000 on June 15, 2007, at 8:03:48

Yes, the sleep deprivation is maddening, but I'm also disillusioned by Parnate's lack of antidepressant effect on me. I still feel fundamentally depressed, zero motivation, obvious avoidance behavior + contending w/ these miserable side effects. It's been almost 11 weeks (5 on 60 mgs), I feel as though I've given this drug more than a fair shake. I'm going to say good-bye to Parnate and hope my doc has something more effective in mind. Open to suggestions.....

Thanks all,

Sophia

 

Re: Advice from Parnate (insomnia) bye bye Parnate » sophia04

Posted by OzLand on June 17, 2007, at 14:06:29

In reply to Re: Advice from Parnate (insomnia) bye bye Parnate, posted by sophia04 on June 16, 2007, at 22:31:33

I don't know what to say other than it sounds like it is not the right one for you. I am now on 40 mg, 20 in the a.m. and 20 at noon. It is working well for me though I still have some instability, and it was recommended I take Lithium for this. I did not want to, but maybe it is what I need. I don't know. I used to take the combo of Parnate with Lithium, and others thought it worked better for me. So, maybe a tricyclic like desipramine would work better for you????

 

Re: Advice from Parnate (insomnia) bye bye Parnate

Posted by sophia04 on June 17, 2007, at 14:52:04

In reply to Re: Advice from Parnate (insomnia) bye bye Parnate » sophia04, posted by OzLand on June 17, 2007, at 14:06:29

> I don't know what to say other than it sounds like it is not the right one for you. I am now on 40 mg, 20 in the a.m. and 20 at noon. It is working well for me though I still have some instability, and it was recommended I take Lithium for this. I did not want to, but maybe it is what I need. I don't know. I used to take the combo of Parnate with Lithium, and others thought it worked better for me. So, maybe a tricyclic like desipramine would work better for you????

Thank you,
I will mention desipramine to my doc. I'm glad you're getting a good response out of parnate. Good luck should you choose lithium too. Amybe my dose at 60mg was too hight. Perhaps as I withdrawal I will respond to a lower dose.

Sophia

 

Re: Advice from Parnate (insomnia) bye bye Parnate

Posted by missjulie on June 19, 2007, at 15:46:57

In reply to Re: Advice from Parnate (insomnia) bye bye Parnate, posted by sophia04 on June 16, 2007, at 22:31:33

Hi Sophia, please let me know what you try next. I have just started Parnate, been on 30 for a week, and am also totally disillusioned. I haven't slept for 7 nights, have dry mouth, and feel totally flat. No relief of depression whatsoever, and certainly no energizing effects. This is SO DISAPPOINTING, I thought this would be the magic bullet. I too have been through everything, this was the last resort before ECT. Are you thinking of trying Nardil, or are you done with MAOIs?
best wishes-Julie

 

Re: Advice from Parnate (insomnia) bye bye Parnate

Posted by malcolm664 on June 19, 2007, at 17:59:49

In reply to Re: Advice from Parnate (insomnia) bye bye Parnate, posted by missjulie on June 19, 2007, at 15:46:57

> Hi Sophia, please let me know what you try next. I have just started Parnate, been on 30 for a week, and am also totally disillusioned. I haven't slept for 7 nights, have dry mouth, and feel totally flat. No relief of depression whatsoever, and certainly no energizing effects. This is SO DISAPPOINTING, I thought this would be the magic bullet. I too have been through everything, this was the last resort before ECT. Are you thinking of trying Nardil, or are you done with MAOIs?
> best wishes-Julie

I would caution you against giving it up so quickly. For one thing, 30 mgs is not even near the theraputic dose. And you also need to be on it for at least 4-5 weeks before the med really starts to kick in.

I've been on it since April 23rd and it took at least about a month before I started to notice any AD effects (Like you, I started on 30 mgs but slowly went up to 60 mg, and just yesterday, my doc told me to go up to 80 mgs/day).

On the downside, yes Parnate definitely wipes you out and causes insomnia. (I actually fell asleep at a traffic light while driving on the way home today). But that can be counteracted to a large degree with coffee (you just have to remember not to let the fatigue stop you from actually making or buying a cup of coffee - the fatigue is that strong).

And yes, I know that caffeine is contraindicated while you're on Parnate, but I've been making pretty strong cups and haven't had any trouble, so I think that the danger is a bit inflated).

And there's another Parnate user on the board who says that even the fatigue tends to diminish with time.

And ever since I've started taking Klonopin and Lunesta, insomnia is no longer a problem.

But I would definitely not give up after just a week, especially since you're only on 30 mgs. That's not enough time for you to evaluate a med, especially an MAOI which tend to take a while for their full effects to become noticeable.

Malcolm

 

Re: Advice from Parnate (insomnia) bye bye Parnate

Posted by missjulie on June 19, 2007, at 18:32:22

In reply to Re: Advice from Parnate (insomnia) bye bye Parnate, posted by malcolm664 on June 19, 2007, at 17:59:49

Thank you Malcolm for your reply. Don't worry, I am not about to give up after the fight I had to get prescribed Parnate at all (seriously, you would not believe - 4 drs, starting with one who most recently treated me for 2 years, flat out refused, FINALLY found new one just to give this a try...) So no I'm not quitting already, no way. Think I read too many paeans to this drug from people saying it was amazing, changed their life, worked from the first day, etc. I got overly hopeful as I am classic atypical/bipolar III and this sure sounded like the answer after YEARS of suffering.
The side effects sure kicked in within hours though... I've got 'em all... besides dry mouth and NO SLEEP I am freezing cold all the time and pee CONSTANTLY (what's up with that??) I am dying to take a sleeping aid but am so paranoid about OTC medicine and food... Lunesta is prescription, right? BTW couldn't agree more about caffeine, drinking diet coke like crazy and no problems there. I can't say I'm more tired than I used to be (that was my main complaint) -- the one thing I haven't got is afternoon fatigue -- just NO SLEEP. For someone who has slept most of their life away this is VERY strange/unnerving. (yes, tried provigil years back, ritalin too, did nothing)
I was just sympathizing with other poster re: insomnia, but would certainly not quit till at least a month at 60. thanks Julie


 

Re: Advice from Parnate (insomnia) bye bye Parnate » missjulie

Posted by psychobot5000 on June 19, 2007, at 23:05:21

In reply to Re: Advice from Parnate (insomnia) bye bye Parnate, posted by missjulie on June 19, 2007, at 15:46:57

Don't give up hope so soon! Parnate usually takes a few weeks to work--has turned countless lives around!

Wishing you luck,
Psychbot

 

Re: Advice from Parnate (insomnia) bye bye Parnate

Posted by sophia04 on June 20, 2007, at 0:48:00

In reply to Re: Advice from Parnate (insomnia) bye bye Parnate, posted by missjulie on June 19, 2007, at 15:46:57

Dear Julie,
Of course give it more time. You may want to try adjusting your dose time. Now that I'm weaning myself off, I'm taking my entire dose (down to 30mg from 60mg now w/ no adverse w/drawal effects) at 9:00 am. This is as manageable as the drug has ever been for me. I'm getting the fatigue slump around 8:00 pm and am actually sleeping through the night all by myself - with no sleep aids. Although it's not like any of them even touched the parnate-induced insomnia.

I initially mourned the decision to give up on Parnate, because I too had high hopes, but with every little pink pill that I don't take, I feel less poisoned and more alive.

Good luck and I will absolutely let you know what move my doc and I decide to make next.

Sophia


> Hi Sophia, please let me know what you try next. I have just started Parnate, been on 30 for a week, and am also totally disillusioned. I haven't slept for 7 nights, have dry mouth, and feel totally flat. No relief of depression whatsoever, and certainly no energizing effects. This is SO DISAPPOINTING, I thought this would be the magic bullet. I too have been through everything, this was the last resort before ECT. Are you thinking of trying Nardil, or are you done with MAOIs?
> best wishes-Julie


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