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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 5 of 5. This is the beginning of the thread.
Posted by dondon on January 24, 2007, at 11:32:13
Can you add an antipsychotic to a dopaminergic med without blocking the effects of the dopaminergic?
Posted by halcyondaze on January 24, 2007, at 14:06:14
In reply to dopaminergics with antipsychotics, posted by dondon on January 24, 2007, at 11:32:13
> Can you add an antipsychotic to a dopaminergic med without blocking the effects of the dopaminergic?
>I am on Parnate and still feel a VERY dopaminergic effect despite taking Seroquel at night.
Same goes for when I was taking Adderall with Seroquel at night.
Posted by med_empowered on January 25, 2007, at 2:41:51
In reply to Re: dopaminergics with antipsychotics, posted by halcyondaze on January 24, 2007, at 14:06:14
it can work..back in the day, these combos were common in one pill. There was Thora-Dex (dexedrine and Thorazine), Eskatrol (compazine/dex), Stelladex (stelazine/dex), so on and so forth. Apparently, these drugs were good for both weight loss AND mood--I guess with careful dosage adjustments, you can get maximum benefits from both meds.
Posted by laima on January 25, 2007, at 9:25:03
In reply to Re: dopaminergics with antipsychotics, posted by med_empowered on January 25, 2007, at 2:41:51
Wow, surprised they don't still do this! Ie, "zyprexadex". That would seem too be an improvement. Weight-neutral anytipsychotics. I guess they'd no longer be taken at night though.
Posted by med_empowered on January 26, 2007, at 2:04:52
In reply to Re: dopaminergics with antipsychotics » med_empowered, posted by laima on January 25, 2007, at 9:25:03
after the whole "speed kills" thing in the 60s, the upper/downer combo pills became less popular; most were withdrawn in the 70s (eskatrol stuck around into the 80s). Docs do still do the upper/downer thing; lots of people are on either ritalin/amphetamines plus an antipsychotic, or Provigil plus an antipsychotic (milder stimulant, same concept). Provigil is expen$ive, but it can cause weight loss in some patients, like those on clozapine, so its useful. What I'd be interested in would be phentermine+atypicals, meridia+atypicals, that sort of thing--modified anorectic drugs plus varying doses of atypicals. Seems like it could help a lot of problems.
This is the end of the thread.
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