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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 10 of 10. This is the beginning of the thread.
Posted by FrequentFryer on November 1, 2005, at 16:11:33
Hi Good people. I just started taking Parnate & must say I love it!!.
Although it makes me quite tired at times..
I was just wondering if anyone takes it at night before bed???
Posted by willyee on November 1, 2005, at 18:22:26
In reply to Parnate Sedation Solution, posted by FrequentFryer on November 1, 2005, at 16:11:33
Not ideal,but when my depression is really bad i start having horrable nightmares,at this time ill take parnate since im much much less likly to have them upon falling asleep with parnate.I believe maois surpress rem.
Normaly you want to avoid this because of that,i dont believe the sleep u get off maoi is healthy so u want to have a more normal stat of sleep as possable.Im not positive on this reasoning though.
Posted by superman on November 2, 2005, at 5:23:24
In reply to Parnate Sedation Solution, posted by FrequentFryer on November 1, 2005, at 16:11:33
Yes, I do take it before bed. 40mg. It makes me really tired too.
The common advice is not to take it later than 3pm (or "so and so" hours before bed)... something about a amphetamine-like metabolite.
I did follow this suggestion for the first while. I experiemnted first of course, and found no matter when I took it, I could barely sleep... yet I would still feel so very tired the few hours after a dose.
Eventually tho the sleep troubles disappeared- within a few weeks or couple months (I assume ones brain adapts to whatever it is from the parnate that keeps you up).
It has been about 5/6 months now and the tiredness has not disappear. I think the fatigue has more to do w/ blood pressure and the vascular system in general than the effects parnate has on the brain. Taking parnate before bed is working fine for me.
Willyee does have a good point tho. In theory (and in his experience it seems) parnate would repress REM sleep (amphetamine metabolites??). I feel most tired 2-6 hours after a dose, and most activated the few hours after that (mentally and physically)... so in my rxperience taking bfr bed works rather well. We'll see if reduced REM sleep catches up with me (note tho that I feel plenty alert and energetic during the day, and I still have lots dreams).
Just thought I'd share. glad to hear its helping and good luck. :)
Ty
> Hi Good people. I just started taking Parnate & must say I love it!!.
> Although it makes me quite tired at times..
> I was just wondering if anyone takes it at night before bed???
Posted by Chairman_MAO on November 2, 2005, at 15:49:51
In reply to Re: Parnate Sedation Solution » FrequentFryer, posted by superman on November 2, 2005, at 5:23:24
A recent study of this very subject has shown no cognitive impairment--memory formation or otherwise--in individuals where complete suppression of REM was induced with phenelzine. This casts profound doubt on the widely accepted theory that REM sleep is integral for memory storage and "housekeeping" tasks.
Posted by FrequentFryer on November 3, 2005, at 2:47:50
In reply to Re: Parnate Sedation Solution » superman, posted by Chairman_MAO on November 2, 2005, at 15:49:51
Thanks guys.
Its funny though Ive taken plenny of methamphetamine before & the last thing it dose is puts me to sleep. And I was pretty heavy insomniac, but on Parnate Im not.
Posted by FrequentFryer on November 3, 2005, at 3:32:56
In reply to Re: Parnate Sedation Solution, posted by FrequentFryer on November 3, 2005, at 2:47:50
Do any of you Drink any Tea / Coffee or suppliments to counteract the sedation?
Im not to worried about the hypertension because I accidently ate heaps of pizza on the weekend & BP was normal.
Posted by EERRIICC on November 3, 2005, at 5:09:42
In reply to Parnate Sedation Solution, posted by FrequentFryer on November 1, 2005, at 16:11:33
Parnate's sedation was so strange it made me feel both mentally and physically weak. I took pure creatine at normal doses and within a few days this fatigue was completely gone. When I ran out of creatine the fatigue returned. There has been some recently published studies that back up my observations. Hopefully, creatine can help anyone suffering from medication fatigue. It should be noted that it has no stimulant qualities.
Good Luck,
Eric
Posted by Declan on November 3, 2005, at 5:40:16
In reply to Re: Parnate Sedation Solution, posted by EERRIICC on November 3, 2005, at 5:09:42
Hello Eric
Are you still doing Strattera to help with your sleep pattern? Ever take Parnate before retiring?
Declan
Posted by superman on November 3, 2005, at 16:08:35
In reply to Re: Parnate Sedation Solution, posted by FrequentFryer on November 3, 2005, at 3:32:56
I take caffein pills to counter the dose i take during the day. It doesn't always work, but im convinced it helps. When I do this + excercise in the morning (before I start to get tired) I almost never feel fatigued.
In my experience, tea makes it worse. I have theories why that is.
> Do any of you Drink any Tea / Coffee or suppliments to counteract the sedation?
>
> Im not to worried about the hypertension because I accidently ate heaps of pizza on the weekend & BP was normal.
Posted by willyee on November 3, 2005, at 18:40:45
In reply to Re: Parnate Sedation Solution, posted by superman on November 3, 2005, at 16:08:35
Same problem here,caffiene tabs at first worked wonders,than either agigated my depression or anxiety,or made me more tired.
Ritalin was next,at first nothing special.But um how so i say this,ritalin taken a certain way has done wonders in that area,i just demeanded it back after giving it up as i miscalculated what was helping.And yess a ritalin taken in that manner,of course not recomending it i dont want to offend u,but i have to say in that mannry wakes u right up from the parnate slouch where u want to run to the nearest counch.
This is the end of the thread.
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