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Dr. Bob is Robert Hsiung, MD,
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Posted by Dave001 on July 21, 2005, at 17:00:07
The first three links are case reports. Although the last one used a double-blind crossover design, I think that the assessment of acute effects from drugs such as the amphetamines is of very limited value for assessing their potential obsessogenic or antiobsessional properties, for the obvious reason that amphetamine-naive subjects will be too euphoric to be bothered by obsessive thoughts. Interesting nonetheless.
I think that evidence of this sort would mainly be of interest to those considering stimulants for reasons unrelated to treatment of obsessive disorders, but wanting to avoid inducing or aggravating obsessional behaviors. The word 'evidence' is perhaps too strong of a connotation to describe the information below.
Dexamphetamine for Obsessive-Compulsive Disorder
http://ajp.psychiatryonline.org/cgi/content/full/160/1/183Adderall for Obsessive-Compulsive Disorder
http://ajp.psychiatryonline.org/cgi/content/full/158/5/818-aCase series: Adderall augmentation of serotonin reuptake inhibitors in childhood-onset obsessive compulsive disorder.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=retrieve&db=pubmed&list_uids=12188985&dopt=AbstractD-amphetamine in obsessive-compulsive disorder
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=retrieve&db=pubmed&list_uids=6412267&dopt=Abstract
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