![[dr. bob]](/dr-bob-sm.gif)
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 2 of 2. This is the beginning of the thread.
Posted by pantt on September 7, 2004, at 11:36:44
I started on Celebrex 6 days ago for a shoulder injury. My depression is almost gone.I don't just feel better. I am getting things done that I just let slide for months and years. I thought it was just my imagination or a kind of mood boost from the shoulder pain easing but I researched it on google and found this article about a trial of celebrex for bipolar depression which provides a possible explanation of an antidepressant effect. I have never been diagnosed bipolar but my depression is very seasonal which some might see as on the bipolar spectrum.
Anyway this is such good news for me I wanted to let you all know in case you've tried everything else-Maybe try this. I'll let you know how long this good mood lasts for me.
Here's the article
http://www.uthscsa.edu/opa/releases/nrel22bMay03.htm
an excerpt:
Celecoxib lowers production of an enzyme called cyclooxygenase-2 (or cox-2). This enzyme, which is produced inside cells throughout the body, is involved in inflammation. Celecoxib inhibits cox-2 in the joints to help relieve pain in patients with degenerative joint disease. "Our patients experience swings from the manic phase to depression," said Dr. Soares, holder of the Krus Endowed Chair in Psychiatry at UTHSC and chief of the division of mood and anxiety disorders. "Bipolar disorder could involve a type of reaction in the brain cells that in some aspects resembles inflammation. By cutting production of cox-2 through the administration of this medicine, we hope to see improvement in the depressive episodes."
Posted by linkadge on September 7, 2004, at 18:13:34
In reply to Celebrex is helping my depression!!, posted by pantt on September 7, 2004, at 11:36:44
Yes I've heard this and similar stories. I heard that celebrax was used as an effective adjunctive in schitsophrenia. It appears that inflamation has a huge role in how the brain regulates neurotransmission.
I have noticed that even aspirin can calm me down some times.Another thing you could try is fish oil, which has antiinflamitory properties too.
Linkadge
This is the end of the thread.
Psycho-Babble Medication | Extras | FAQ
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.org
Script revised: February 4, 2008
URL: http://www.dr-bob.org/cgi-bin/pb/mget.pl
Copyright 2006-17 Robert Hsiung.
Owned and operated by Dr. Bob LLC and not the University of Chicago.