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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 6 of 6. This is the beginning of the thread.
Posted by 1980Monroe on July 21, 2004, at 15:34:27
I know parkinson's, but i dont know the rest.
Can it be prescribed as an antidepressant? I've heard some people have tooken it with ADHD meds too also.
Does anyone know what im talking about.
Posted by King Vultan on July 22, 2004, at 7:55:33
In reply to What is Selegine prescribed for?, posted by 1980Monroe on July 21, 2004, at 15:34:27
> I know parkinson's, but i dont know the rest.
>
> Can it be prescribed as an antidepressant? I've heard some people have tooken it with ADHD meds too also.
>
> Does anyone know what im talking about.Yes, it can be used as an antidepressant, but it is apparently metabolized to amphetamine and methamphetamine--must be why some users are so enthusiastic about it. I tend to look askance at amphetamine-type drugs myself; although, I probably am going to be switching from Nardil to Parnate, the latter of which does have a stimulant-type character, with a structure very close to that of amphetamine itself.
Todd
Posted by Aserone on July 24, 2004, at 15:38:02
In reply to Re: What is Selegine prescribed for?, posted by King Vultan on July 22, 2004, at 7:55:33
> Yes, it can be used as an antidepressant, but it is apparently metabolized to amphetamine and methamphetamine--must be why some users are so enthusiastic about it. I tend to look askance at amphetamine-type drugs myself; although, I probably am going to be switching from Nardil to Parnate, the latter of which does have a stimulant-type character, with a structure very close to that of amphetamine itself.
>
> Todd
>It's metabolized to the more or less inactive levo isomer of methamphetamine/amphetamine. So it does not work the same, and therefore thats not why some people "want" this med. You can't abuse it and it doesn't cause a high. Parnate's effect are much more like the amphetamines.
Posted by Ktemene on July 24, 2004, at 23:02:15
In reply to Re: What is Selegine prescribed for?, posted by Aserone on July 24, 2004, at 15:38:02
> > Yes, it can be used as an antidepressant, but it is apparently metabolized to amphetamine and methamphetamine--must be why some users are so enthusiastic about it. I tend to look askance at amphetamine-type drugs myself; although, I probably am going to be switching from Nardil to Parnate, the latter of which does have a stimulant-type character, with a structure very close to that of amphetamine itself.
> >
> > Todd
> >
>
> It's metabolized to the more or less inactive levo isomer of methamphetamine/amphetamine. So it does not work the same, and therefore thats not why some people "want" this med. You can't abuse it and it doesn't cause a high. Parnate's effect are much more like the amphetamines.
I take 5 mg Selegiline and 10 to 20 mg Adderall every day. I am not enthusiastic about Selegiline because of the l-amphetamine metabolites, which are a tiny amount. I am enthusiastic because Selegiline gives me more energy and focus than any of the ten or so other meds I have tried, and that includes Adderall. Adderall does not energize me; it just gives me a calm and collected feeling. I don't know why Selegiline is so activating, but it is definitely not because it is metabolized to amphetamine.
Posted by KaraS on July 27, 2004, at 3:34:49
In reply to Re: What is Selegine prescribed for?, posted by Ktemene on July 24, 2004, at 23:02:15
> > > Yes, it can be used as an antidepressant, but it is apparently metabolized to amphetamine and methamphetamine--must be why some users are so enthusiastic about it. I tend to look askance at amphetamine-type drugs myself; although, I probably am going to be switching from Nardil to Parnate, the latter of which does have a stimulant-type character, with a structure very close to that of amphetamine itself.
> > >
> > > Todd
> > >
> >
> > It's metabolized to the more or less inactive levo isomer of methamphetamine/amphetamine. So it does not work the same, and therefore thats not why some people "want" this med. You can't abuse it and it doesn't cause a high. Parnate's effect are much more like the amphetamines.
>
>
> I take 5 mg Selegiline and 10 to 20 mg Adderall every day. I am not enthusiastic about Selegiline because of the l-amphetamine metabolites, which are a tiny amount. I am enthusiastic because Selegiline gives me more energy and focus than any of the ten or so other meds I have tried, and that includes Adderall. Adderall does not energize me; it just gives me a calm and collected feeling. I don't know why Selegiline is so activating, but it is definitely not because it is metabolized to amphetamine.
>
>And, as opposed to amphetamines, it prevents neurotoxicity rather than causing it!!
Posted by platinumbride on July 27, 2004, at 14:32:16
In reply to What is Selegine prescribed for?, posted by 1980Monroe on July 21, 2004, at 15:34:27
I had a brief stint with selegiline and an amino acid called phenylalanine. Apparently there is at least one study which showd something like 90% improvement rate with it's subjects.
Prior to that my doc ordered a cream to be compounded with the med, hoping it wold behave as the patch has for some peole. (I believe the patch is called ensam). I'm not sure if it didn't absorb well, but I really just gave up on it, perhaps prematurely.
I guess it is energizing, if you consider insomnia energizing.I should add that there were and are a lot of "womanly" hormonal problems going on, and that may be why I didn't respond to the drug. Or perhaps it simply was not the drug for me. Or maybe if I had been on a decent mood stablizer it would have worked.....I just don't know.
I haven't heard about anything vis a vis selegeline and ADHD.
Word has it tht it was originally created as an antidepressant but found to be rather ineffective in that regard (ha- tell that to the people who get relief from it). In the end, it was pretty much relegated to the arena of Parkinson's, but now there is hope that it will come back as the aforementioned patch, where the med will bypass the GI system and thus render safe to take without following the MAOI diet.
Hope this helps,
Diane
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