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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 8 of 8. This is the beginning of the thread.
Posted by colin wallace on June 20, 2004, at 7:50:17
Hi Guys,
Need to gleen some advice here concerning nardil and parnate.
These two now seem to be the only AD's that I haven't given a try at some point, and although I have been free of the worst of my severe BP11 depressions(rapid cycling)until recently, the loss of my brother earlier this year in Iraq whilst working for an aid agency (actually, 'loss' here is just a euphemism for murder)has sent me completely over the edge and into a depression that I now have very little interest left in fighting.
What I need basically is an antidepressant with a canonball punch, and one which is marginally less likely to trip my hairtrigger hypomania(usually dysphoric).
I've decided on either nardil or parnate as I don't have the time or inclination to mess around anymore, and although I know full well that hypomania is a highly idiosyncratic reaction,some insight might be helpful.
Also,I'm going to opt for a failsafe moodstabilizer, and some experiences of how zyprexa or seroquel stack up against valproate would be good.Cheers,
Col.
Posted by Maxime on June 20, 2004, at 19:04:28
In reply to nardil/parnate=manic likelihood?, posted by colin wallace on June 20, 2004, at 7:50:17
Hi, I am sorry about your brother.
I'm bipolar and I am on Parnate and it doesn't make me manic. I have gone manic but not as a result of the Parnate. When I did, I was able to reduce the Parnate which is the good thing about Parnate is that it has a short half life so you can really play with the dosage depending on if you are cycling or not.
I use trileptal as a mood stabiliser.
Good luck to you.
Lost
> Hi Guys,
>
> Need to gleen some advice here concerning nardil and parnate.
> These two now seem to be the only AD's that I haven't given a try at some point, and although I have been free of the worst of my severe BP11 depressions(rapid cycling)until recently, the loss of my brother earlier this year in Iraq whilst working for an aid agency (actually, 'loss' here is just a euphemism for murder)has sent me completely over the edge and into a depression that I now have very little interest left in fighting.
> What I need basically is an antidepressant with a canonball punch, and one which is marginally less likely to trip my hairtrigger hypomania(usually dysphoric).
> I've decided on either nardil or parnate as I don't have the time or inclination to mess around anymore, and although I know full well that hypomania is a highly idiosyncratic reaction,some insight might be helpful.
> Also,I'm going to opt for a failsafe moodstabilizer, and some experiences of how zyprexa or seroquel stack up against valproate would be good.
>
> Cheers,
>
> Col.
Posted by crazychickuk on June 21, 2004, at 6:41:42
In reply to Re: nardil/parnate=manic likelihood?, posted by Maxime on June 20, 2004, at 19:04:28
hi sorry i dont have any experience with parnate or nardil but i am intrugued to know wat affects it has?
i am so so very sorry to hear about your brother...
Posted by colin wallace on June 21, 2004, at 14:54:07
In reply to Re: nardil/parnate=manic likelihood?, posted by Maxime on June 20, 2004, at 19:04:28
> Hi, I am sorry about your brother.
>
> I'm bipolar and I am on Parnate and it doesn't make me manic. I have gone manic but not as a result of the Parnate. When I did, I was able to reduce the Parnate which is the good thing about Parnate is that it has a short half life so you can really play with the dosage depending on if you are cycling or not.
>
> I use trileptal as a mood stabiliser.
>
> Good luck to you.
>
> Lost
>Hi there,
Thanks for the reply.I use Trileptal as a mood stabilizer right now too.I like the stuff as I can still think clearly (900mg) and there are very few med. interactions.It didn't stop my wellbutrin induced mania however, but on reflection I think perhaps only a general anaesthetic would have managed that feat.
As we'll shortly be following the same med. regimen, I'd be interested to hear if you've had any side effects to either med.?
I got some nasty headaches on Trileptal for ages, but I'm glad I stuck it out.
Cheers,Col.
Posted by colin wallace on June 21, 2004, at 15:01:53
In reply to Re: nardil/parnate=manic likelihood?, posted by crazychickuk on June 21, 2004, at 6:41:42
Hi there CC,
> hi sorry i dont have any experience with parnate or nardil but i am intrugued to know wat affects it has?
>>>>>Well, I'm knowledgable enough on the 'theory' behind each of these meds-but I'll let ya know how it actually pans out in practice for me ...:o
> i am so so very sorry to hear about your brother...
Thanks for the kind thoughts.I never thought Iraq would actually touch me personally, 'cos these things always happen to someone else don't they:(
seeya,
Col.
Posted by Maxime on June 21, 2004, at 19:46:28
In reply to Re: nardil/parnate=manic likelihood? » Maxime, posted by colin wallace on June 21, 2004, at 14:54:07
Hello again.
Let's see. I tried lithium but was always going toxic on it. There was either too or too little of it in my blood. Depakote gave me a rash. Topomax made me psychotic. Tegretol made me nauseous and I had trouble walking a straight line plus it's contraindicated with MAOIs. All the antipsychotics made me lactate. Neurontin gave me serious edema. Lamictal made me more depressed. Trileptal has been the only one that works and that doesn't have a bunch of nasty side effects for me. Plus, like you, my mania is dysphoric and I find it good for that.
So that is the run down of the stabiliser I have tried and their effect on me.I'm treatment resistent when it comes to depression and have been on all the SSRIs and everything in between. Thank goodness the Parnate provided relief. I still feel depressed but without it I probably would be able to scrape myself off the ground!
When will you start your MAOI?
Maxime
> > Hi, I am sorry about your brother.
> >
> > I'm bipolar and I am on Parnate and it doesn't make me manic. I have gone manic but not as a result of the Parnate. When I did, I was able to reduce the Parnate which is the good thing about Parnate is that it has a short half life so you can really play with the dosage depending on if you are cycling or not.
> >
> > I use trileptal as a mood stabiliser.
> >
> > Good luck to you.
> >
> > Lost
> >
>
> Hi there,
>
> Thanks for the reply.I use Trileptal as a mood stabilizer right now too.I like the stuff as I can still think clearly (900mg) and there are very few med. interactions.It didn't stop my wellbutrin induced mania however, but on reflection I think perhaps only a general anaesthetic would have managed that feat.
> As we'll shortly be following the same med. regimen, I'd be interested to hear if you've had any side effects to either med.?
> I got some nasty headaches on Trileptal for ages, but I'm glad I stuck it out.
>
>
> Cheers,
>
> Col.
Posted by colin wallace on June 22, 2004, at 7:03:21
In reply to Re: nardil/parnate=manic likelihood?, posted by Maxime on June 21, 2004, at 19:46:28
> Hello again.
>
> Let's see. I tried lithium but was always going toxic on it. There was either too or too little of it in my blood. Depakote gave me a rash. Topomax made me psychotic. Tegretol made me nauseous and I had trouble walking a straight line plus it's contraindicated with MAOIs. All the antipsychotics made me lactate. Neurontin gave me serious edema. Lamictal made me more depressed. Trileptal has been the only one that works and that doesn't have a bunch of nasty side effects for me. Plus, like you, my mania is dysphoric and I find it good for that.
> So that is the run down of the stabiliser I have tried and their effect on me.
>
> I'm treatment resistent when it comes to depression and have been on all the SSRIs and everything in between. Thank goodness the Parnate provided relief. I still feel depressed but without it I probably would be able to scrape myself off the ground!
>
> When will you start your MAOI?
>
> Maxime
>
>
Maxime,You're symptoms mirror mine.I'm highly treatment resistant bipolar 11(rapid cycling nowadays), and when foul weather strikes I'm crippled within days.
Lamictal worked well for me, although I had to go as high as 600mg before abandoning it finally after two years.I walked like a clown on it, but hey, I was a happy clown at least!Neurontin is okay for me, very calmimg, but not enough no combat a dysphoric bout of hypomania.
Hated lith. etc, and became hypo. and more depressed/angry on every other class of AD(must have tried nigh on 15 or so I reckon!!)
And oh, I 'll be starting Parnate as soon as it arrives in the post, 'cos I pretty much gave up on psychs. They've all ended up causing me to worsen by idiotic misdiagnosis of my obvious symptoms in the past.That's life in the UK (psych.)healthcare system I'm afraid.The NHS psychs all seem to be friggin' mindless droogs who got their qualifications from tokens in a packet of frosties breakfast cereal.Hmmm.
Food for thought.Bye for now,
best,
Col.
Posted by Dr. Bob on June 22, 2004, at 16:40:16
In reply to nardil/parnate=manic likelihood?, posted by colin wallace on June 20, 2004, at 7:50:17
> the loss of my brother earlier this year in Iraq whilst working for an aid agency (actually, 'loss' here is just a euphemism for murder)has sent me completely over the edge and into a depression that I now have very little interest left in fighting.
Sorry to interrupt, but FYI, I've reposted the above at Psycho-Babble Grief to see if there might be more responses on that aspect there. Here's a link:
http://www.dr-bob.org/babble/grief/20040220/msgs/359170.html
Thanks,
Bob
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