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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 11 of 11. This is the beginning of the thread.
Posted by Larry Hoover on May 29, 2003, at 10:53:28
Something is different this year.....
I've had severe, even incapacitating, inhalant allergies to pollens and spores since the early 70's. It's just a fact of life for me.
This year, I find myself forgetting to even use an antihistamine.... I don't know what's going on, but I ain't upset by it.
Lar
Posted by Larry Hoover on May 29, 2003, at 11:32:50
In reply to allergic rhinitis (hayfever), and supplements?, posted by Larry Hoover on May 29, 2003, at 10:53:28
> Something is different this year.....
>
> I've had severe, even incapacitating, inhalant allergies to pollens and spores since the early 70's. It's just a fact of life for me.
>
> This year, I find myself forgetting to even use an antihistamine.... I don't know what's going on, but I ain't upset by it.
>
> LarMaybe this is the answer.....
From: http://www.pemphigus.org/am_nicotinamide.html
"Nicotinamide inhibits polymorphonuclear cell (PMN) and eosinophil chemotaxis and blocks IgE-mediated histamine release and mast cell degranulation."The research into this effect was done in the early '70s!!!! Why on Earth did it just fade away?
Maybe B-3 metabolism is one of my fundamental health issues....
Lar
Posted by Larry Hoover on May 29, 2003, at 12:51:25
In reply to allergic rhinitis (hayfever), and supplements?, posted by Larry Hoover on May 29, 2003, at 10:53:28
> Something is different this year.....
>
> I've had severe, even incapacitating, inhalant allergies to pollens and spores since the early 70's. It's just a fact of life for me.
>
> This year, I find myself forgetting to even use an antihistamine.... I don't know what's going on, but I ain't upset by it.
>
> LarOk, zinc inhibits histamine release from mast cells, and also enhances clearance of histamine from inter-cellular spaces (e.g. synapses) in brain tissue.
I know I don't have good zinc metabolism, as my taste and smell diminish drastically unless I routinely supllement with zinc.
Lar
Posted by samplemethod on May 29, 2003, at 12:55:49
In reply to Re: zinc, too, posted by Larry Hoover on May 29, 2003, at 12:51:25
Does methylation affect hista levels?
> > Something is different this year.....
> >
> > I've had severe, even incapacitating, inhalant allergies to pollens and spores since the early 70's. It's just a fact of life for me.
> >
> > This year, I find myself forgetting to even use an antihistamine.... I don't know what's going on, but I ain't upset by it.
> >
> > Lar
>
> Ok, zinc inhibits histamine release from mast cells, and also enhances clearance of histamine from inter-cellular spaces (e.g. synapses) in brain tissue.
>
> I know I don't have good zinc metabolism, as my taste and smell diminish drastically unless I routinely supllement with zinc.
>
> Lar
>
Posted by Larry Hoover on May 29, 2003, at 13:07:08
In reply to Re: zinc, too, posted by samplemethod on May 29, 2003, at 12:55:49
> Does methylation affect hista levels?
As near as I can tell, methylation capacity is positiviely correlated with histamine destruction rate. But, as methylation capacity will simultaneously affect a multitude of other processes, I can't see how you can isolate the effect.
See also:
http://www.dr-bob.org/babble/20030525/msgs/229849.htmlLar
Posted by McPac on May 29, 2003, at 20:58:11
In reply to Re: Niacinamide again!, posted by Larry Hoover on May 29, 2003, at 11:32:50
"The research into this effect was done in the early '70s!!!! Why on Earth did it just fade away?"
The drug co's can't profit from it...but I don't recall the natural community talking about niacinamide/allergies either
Posted by McPac on May 29, 2003, at 21:02:52
In reply to Re: zinc, too, posted by Larry Hoover on May 29, 2003, at 12:51:25
"I know I don't have good zinc metabolism, as my taste and smell diminish drastically unless I routinely supllement with zinc".
Zinc deficiency can cause depression also.
With your allergy problems, have you ever set out to reduce your histamine levels? (Lar, by the way, after high histamine levels were reduced significantly, shouldn't allergic-type problems greatly diminish?)
Posted by Larry Hoover on May 30, 2003, at 16:29:56
In reply to Lar, Re: Niacinamide again!, posted by McPac on May 29, 2003, at 20:58:11
> "The research into this effect was done in the early '70s!!!! Why on Earth did it just fade away?"
>
> The drug co's can't profit from it...but I don't recall the natural community talking about niacinamide/allergies eitherThe research was done overseas, but still.....
Lar
Posted by Larry Hoover on May 30, 2003, at 16:34:46
In reply to Larry, Re: zinc, too, posted by McPac on May 29, 2003, at 21:02:52
> "I know I don't have good zinc metabolism, as my taste and smell diminish drastically unless I routinely supllement with zinc".
>
> Zinc deficiency can cause depression also.Oh, fer sure. It's just that I have a convenient "zinc indicator" in my taste buds. Zinc is folded into the tips of the sensory molecules in the mouth and nose. If your body is running short on zinc, they're kind of a sacrificial lamb, one of the first zinc-dependent processes to get cut back. The life span of your taste buds/olfactory receptors is about two weeks, so there's a bit of a lag both going and coming.
> With your allergy problems, have you ever set out to reduce your histamine levels? (Lar, by the way, after high histamine levels were reduced significantly, shouldn't allergic-type problems greatly diminish?)
I think there's a big difference between CNS histamine and peripheral histamine, just as there's a difference between CNS serotonin and peripheral serotonin. Same chemical, vastly different effects.
Some of the things I'm doing are likely to downregulate both systems, but I think that they more generally require different strategies altogether.
Lar
Posted by dave40252 on June 2, 2003, at 11:35:07
In reply to Re: Lar, Re: Niacinamide again!, posted by Larry Hoover on May 30, 2003, at 16:29:56
I understand that Niacinamide, rather than plain niacin is what you should try for anxiety. Would inositol hexanicotinate, which is promoted as a safer version of niacin work like Niacinamide, or is like niacin?
Thanks for the help
Posted by Larry Hoover on June 3, 2003, at 8:23:29
In reply to Re: Lar, Re: Niacinamide Question, posted by dave40252 on June 2, 2003, at 11:35:07
> I understand that Niacinamide, rather than plain niacin is what you should try for anxiety. Would inositol hexanicotinate, which is promoted as a safer version of niacin work like Niacinamide, or is like niacin?
>
> Thanks for the helpInositol hexanicotinate is six nicotinic acids (niacin) bonded to one inositol. It's slow release niacin (so it's far less likely to do the flush thing).
Niacinamide has no substitute.
Lar
This is the end of the thread.
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