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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 7 of 7. This is the beginning of the thread.
Posted by GABBI X2 on October 10, 2002, at 15:55:54
I had a freaky time of it when Remeron was added to my 150mgs Effexor. Freaky is about as clinical as I can get, my apologies.
I didn't investigate Remeron at all, I'm ashamed to say, it was given to me by a G.P. because I was going Mad from effexor and assumed anything would help.
I felt like an drunk on speed. Incredibly lethargic, heart racing, trembling, verging on paranoid, and have hardly any memory of that entire week.
There you have my scientific opinion.
I didn't stay on the Remeron long enough to see if there would have been any psychological benefitNot that anybody asked but, I can be added to the "Effexor made me behave as If I was posessed, list"
Out of 10 medications by far the worst as for both physical and psychological side-effects.
Posted by GABBI X2 on October 10, 2002, at 16:02:58
In reply to Remeron and Effexor and Effexor Hell., posted by GABBI X2 on October 10, 2002, at 15:55:54
I didn't want to make you nervous with my effexor experience, the signs of my impending "posession" started within my first week. It's worked well for many people I know. It simply wasn't right for me, (or for anyone around me for that matter.)
Posted by Jonathan on October 10, 2002, at 21:09:12
In reply to Remeron and Effexor and Effexor Hell., posted by GABBI X2 on October 10, 2002, at 15:55:54
Hi Gabbi :)
You don't say whether you tried Remeron™ (mirtazapine) recently. I took it for 3 or 4 months last spring and it was disastrous for me, too: it brought me dangerously close to suicide for only the second time in my life; the first was more than 13 years earlier (though, as you said for Effexor™, I know it has helped many people).
When my pdoc told me to stop taking Remeron, he immediately started me on Manerix™ (moclobemide), which was a spectacular but short-lived success: it pulled me out of the very deep pit I was then in within only five days, but this dramatic improvement faded after a further couple of weeks; however, I still went on getting considerable benefit from Manerix for more than a year. For me, it was worth taking for the long-term effects alone, and it was the only AD I've tried that was totally without adverse effects.
You posted about a week ago that you might be starting Manerix soon.
I've been plagued by guilt for nearly a year because I never answered this post — http://www.dr-bob.org/babble/20011202/msgs/86491.html — by someone whose boyfriend had the same spectacularly positive response as I did to Manerix immediately after Remeron. I also found this similar report in the archives — http://www.dr-bob.org/babble/20010605/msgs/65966.html .
I'm pretty sure that this effect must be due to moclo-elevated NE and/or 5-HT acting on some of the many receptors which have previously been blocked and thus upregulated by Remeron (I suspect post-synaptic NE-alpha-2). I don't know if your brief exposure to Remeron would be enough to upregulate the relevant receptors (perhaps not) but it may be worth thinking about if your pdoc is still considering Manerix.
I'm glad you're out of hospital and back online: although I haven't been able for the last year to cope with the immediacy of online chat, I missed your posts on Social. I hope you're beginning to get over the worst of the Effexor withdrawal: carbamazepine (Tegretol™) — or better its newer, safer cousin oxcarbazepine (Trileptal™) — is reputed to be good for med-induced tinnitus.
Get well soon :)
Jonathan.
Posted by GABBI X2 on October 10, 2002, at 21:51:55
In reply to Manerix™ after Remeron™ » GABBI X2, posted by Jonathan on October 10, 2002, at 21:09:12
John
Thank-you, you really lifted my spirits.
I was questioning trying the Manerix, and know of no-one whose tried it, the personal stories have convinced me to give it a shot.
Thanks for remembering my post.
Wow, all I can say is thank-you again and again.Yeah I know its the Med board I'm going now
Posted by Jonathan on October 10, 2002, at 22:51:00
In reply to RE: Remeron And Manerix » Jonathan, posted by GABBI X2 on October 10, 2002, at 21:51:55
Gabbi
I'm delighted that I had something helpful to say to someone who has done as much as you have towards making this place such a friendly, welcoming refuge in cyberspace.
Tina also posted her positive impressions of Manerix for you on the Social board — http://www.dr-bob.org/babble/social/20020924/msgs/30746.html
I think the main reason you don't hear more success stories about it is because most people who post here are in the USA, where it's not approved as it is here in the UK and in Canada.
As I said, it did eventually stop working well enough for me, but only after more than a year, and even then it was better than the tricyclic I'm now stuck with: perhaps I need one of the older, irreversible MAOIs like Parnate (tranylcypromine) now.
I'm glad you're going to try Manerix and hope it will work as well for you as it first did for me.
Sending good thoughts and prayers your way :)
Jonathan.
Posted by jyl on October 11, 2002, at 9:57:05
In reply to One more thing.., posted by GABBI X2 on October 10, 2002, at 16:02:58
wow!
day 7 of effexor75mg
trazodone at night.
i cry lots-pace around like i am going mad!
hands shake-think the bees on the patio are out
to get me!
on the plus-can get out of bed!
stopped pulling my hair out.
sober
slept two nights in a row!
jyl
any comments would be soooo helpful.
Posted by GABBI X2 on October 11, 2002, at 12:54:46
In reply to effexor question to one more thing..., posted by jyl on October 11, 2002, at 9:57:05
This is the end of the thread.
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