Psycho-Babble Medication Thread 113744

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Hardcore headache on Wellbutrin

Posted by MarkCSF on July 25, 2002, at 22:18:23

Man, I started Wellbutrin a couple weeks ago and have gotten a constant headache thats only gotten worse. It never goes away. Anyone experience this and does it go away? Im going to quit this tommorow, I cant take it anymore. I took Wellbutrin for a couple months a couple years ago but didnt have this headache at all..

 

Re: Hardcore headache on Wellbutrin

Posted by Shawn. T. on July 26, 2002, at 0:39:53

In reply to Hardcore headache on Wellbutrin, posted by MarkCSF on July 25, 2002, at 22:18:23

That is a possible side effect; I'm not entirely certain why it happens to some people and not others. I'll give it a shot though. One idea is that it could be a result of increased activation of alpha-1-adrenergic (noradrenaline type) receptors. Repeated activation of this receptor could result in a constant headache like the one you describe (as a result of vasoconstriction perhaps). Perhaps this receptor has become more sensitive in the recent past. If you have recently developed a problem with hypertension, then that could definitely lead to the change. You should either decrease your dosage or try something else. If you're taking say 300mg/day already, then that is definitely too much. I didn't increase my total daily dosage over 150mg/day until more than a month after I began taking Wellbutrin. Your headache should go away after a while, but I wouldn't want to wait it out either. It takes a certain amount of time for neurons to adjust to various changes in the synapse; Wellbutrin is a drug that often seems to take a while for a change in gene transcription to occur.

Shawn

 

I had the same thing happen

Posted by rainbowlight on July 28, 2002, at 21:03:56

In reply to Hardcore headache on Wellbutrin, posted by MarkCSF on July 25, 2002, at 22:18:23

Worst continual headache of my life. I would lay in bed sobbing it hurt so bad. I only lasted a week on the med, couldn't deal with it anymore. Just wanted to let you know your not alone.


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