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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 4 of 4. This is the beginning of the thread.
Posted by IsoM on May 15, 2002, at 2:12:30
Boy, thanks for jogging my memory. KK is sweet to say I'm intelligent but my memory is terrible for everyday stuff. When my adrafinil kicks in again, it'll be better.
Yes, I read over the articles. Basically, what was being said is that serotonin has far-reaching effects in proper brain formation & function.
During fetal & early post-natal brain formation, serotonin plays a major role in the development of a normal & healthy anxiety or stress response. Without it, the brain wouldn't develop any stress response (or anxiety) but an excess during early brain development, post-natally, can leave such an individual overly sensitive to excess anxiety (at least in mice but most likely in humans too).
It goes on to explain how scientists were able to test these ideas by knocking out a specific gene in mice that controlled serotonin response in cells of the mice's developing brains to be able to compare them to mice who developed normally.All the new research was pretty interesting but of no relevant value to those now suffering from anxiety. At this point of time, anxiolytic (antianxiety) drugs are the only means of controlling it. The scientists involved hope to make use of their studies in future methods of understanding anxiety better. Sorry I can't give you something more positive & concrete. The point of the article was to show how much more a role neurotransmitters can have in development than previously thought.
Posted by BobS. on May 15, 2002, at 9:41:08
In reply to for BOB S. - Nature articles, posted by IsoM on May 15, 2002, at 2:12:30
Thanks. That's how I read it, but there was some hint that increasing serotonin for the "deprived" test animals was beneficial for them. After 55 years of anxiety that comes and goes and then a recent hell on SSRIs, now on BZD monotherapy, I was shocked to see these articles. Because I was/am pretty much convinced that SSRIs for anxiety, not caused by depression, is more marketing than medicine. Hell on SSRIs, notwithstanding, I wonder if I made a mistake opting for BDZs only.
Regards,
BobS.
Posted by MomO3 on May 15, 2002, at 12:25:24
In reply to Re: for BOB S. - Nature articles, posted by BobS. on May 15, 2002, at 9:41:08
I started prozac in 1989 and took it on and off for 9 yrs. In 1995 I started experiencing anxiety attacks, by 1998 I noticed that my anxiety was greater ON the Prozac then off, and I stopped taking it.
I know I have been somewhat of a lab rat for long term use of prozac, now I am wondering about the serotonin syndrome...
> Thanks. That's how I read it, but there was some hint that increasing serotonin for the "deprived" test animals was beneficial for them. After 55 years of anxiety that comes and goes and then a recent hell on SSRIs, now on BZD monotherapy, I was shocked to see these articles. Because I was/am pretty much convinced that SSRIs for anxiety, not caused by depression, is more marketing than medicine. Hell on SSRIs, notwithstanding, I wonder if I made a mistake opting for BDZs only.
> Regards,
> BobS.
Posted by BobS. on May 15, 2002, at 19:44:37
In reply to Re: for BOB S. - Nature articles, posted by MomO3 on May 15, 2002, at 12:25:24
Mom03,
Serotonin syndrome is caused by taking more than one medication that has an additive effect of increasing serotonin, which is too much of good thing and consequently a problem. Like too much beer.The issue I asked IsoM to look at, in Nature Magazine, has relevance to the concept of treating "pure" anxiety disorder patients (no depression to speak of) with SSRIs. I felt I was on the right track getting off SSRIs because of the side effects and the fact that they did not seem to help my anxiety. After reviewing the articles I wondered if I made a mistake. BTW, I was on Prozac and just like you felt it increased my anxiety. So the world thinks that SSRIs are good for anxiety and I disagree. I hope that I am correct, but the articles shook my faith.
This is the end of the thread.
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