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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 5 of 5. This is the beginning of the thread.
Posted by Fred Potter on March 27, 2001, at 15:35:20
Where treatment resistant depressed people get relief (as from the augmentation of an SSRI with Naltrexone) I believe their response is quite unlikely to be a placebo response. This is because they've got used to drugs NOT working. Also drug responses working much more quickly than expected would make the placebo affect unlikely. This happened to me with Moclobemide, unfortunately it stopped working equally quickly.
I don't trust herbs so I was reluctant to start SJW (tincture). As I wasn't expecting it to work I was pleasantly surprised when it did. However, Prozac was making me worse without the Naltrexone, so stopping that may have helped. So why did I give up Naltrexone? Well it's terribly expensive in New Zealand, where it's seen only of use in avoiding opium dens, not that there are any here. Ramble . . .
Fred
Posted by SalArmy4me on March 29, 2001, at 4:38:15
In reply to Treatment resistance and placebo effects, posted by Fred Potter on March 27, 2001, at 15:35:20
You're looking for a quick fix, aren't you...I can tell by the way you write. There are no quick fixes; abandon the naltrexone idea completely because its not an antidepressant anyway; try an SSRI or venlafaxine before you run out of money.
> Where treatment resistant depressed people get relief (as from the augmentation of an SSRI with Naltrexone) I believe their response is quite unlikely to be a placebo response. This is because they've got used to drugs NOT working. Also drug responses working much more quickly than expected would make the placebo affect unlikely. This happened to me with Moclobemide, unfortunately it stopped working equally quickly.
>
> I don't trust herbs so I was reluctant to start SJW (tincture). As I wasn't expecting it to work I was pleasantly surprised when it did. However, Prozac was making me worse without the Naltrexone, so stopping that may have helped. So why did I give up Naltrexone? Well it's terribly expensive in New Zealand, where it's seen only of use in avoiding opium dens, not that there are any here. Ramble . . .
>
> Fred
Posted by Fred Potter on March 29, 2001, at 19:22:20
In reply to Re: Treatment resistance and placebo effects » Fred Potter, posted by SalArmy4me on March 29, 2001, at 4:38:15
Don't try and read betweeen the lines of my post. I wrote what I wrote. All the SSRIs poop-out and then make me worse, as did Moclobemide. Naltrexone with Prozac worked. I was trying to make helpful comments.
How do you know there are no quick fixes? It's almost impossible to prove the absence of something. There are certainly plenty of long-term so-called fixes which *don't* work. I don't like your tone
Posted by JahL on March 29, 2001, at 19:51:28
In reply to Treatment resistance and placebo effects, posted by Fred Potter on March 27, 2001, at 15:35:20
> > Where treatment resistant depressed people get relief (as from the augmentation of an SSRI with Naltrexone) I believe their response is quite unlikely to be a placebo response. This is because they've got used to drugs NOT working. Also drug responses working much more quickly than expected would make the placebo affect unlikely. This happened to me with Moclobemide, unfortunately it stopped working equally quickly.
I agree.
> > I don't trust herbs so I was reluctant to start SJW (tincture). As I wasn't expecting it to work I was pleasantly surprised when it did. However, Prozac was making me worse without the Naltrexone, so stopping that may have helped. So why did I give up Naltrexone? Well it's terribly expensive in New Zealand, where it's seen only of use in avoiding opium dens, not that there are any here. Ramble . . .Is the SJW as good as the Prozac+Naltrexone?
What's yr dx, if I may ask?J.
Posted by Fred Potter on March 29, 2001, at 19:57:08
In reply to Re: Treatment resistance and placebo effects » Fred Potter, posted by JahL on March 29, 2001, at 19:51:28
Panic, anxiety, moderate depression and a tendency to self-medicate with alcohol. So Naltrexone was a 2 edged sword for me. With Prozac Naltrexone made me feel great. And the effect was sustained. The effect I notice with SJW may be because I've given up Prozac.
This is the end of the thread.
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