Psycho-Babble Medication Thread 53215

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moclobemide and desyred URGENT please

Posted by Sigolene on February 3, 2001, at 1:11:15

Has someone already taken together 25 or 50 mg desyred and 300 mb moclobémide (manerix, aurorix) ?
it's supposed to be countaindicated but i can't sleep with moclobémide and i WANT to try it.

Sigolène

 

Re: I mean desyrel no desyred of course, sorry.

Posted by Sigolene on February 3, 2001, at 1:15:31

In reply to moclobemide and desyred URGENT please, posted by Sigolene on February 3, 2001, at 1:11:15

> Has someone already taken together 25 or 50 mg desyred and 300 mb moclobémide (manerix, aurorix) ?
> it's supposed to be countaindicated but i can't sleep with moclobémide and i WANT to try it.
>
> Sigolène

 

Re: I mean desyrel no desyred of course, sorry.

Posted by PatJ. on February 4, 2001, at 17:05:22

In reply to Re: I mean desyrel no desyred of course, sorry., posted by Sigolene on February 3, 2001, at 1:15:31

> > Has someone already taken together 25 or 50 mg desyred and 300 mb moclobémide (manerix, aurorix) ?
> > it's supposed to be countaindicated but i can't sleep with moclobémide and i WANT to try it.
> >
> > Sigolène
Hi Sigolene,
I don't know about the drugs that you mentioned but I have started taking 150 mgs. of kavakava for relaxation and sleep and I find it has helped a lot.

 

Re: moclobemide and desyred URGENT please

Posted by SLS on February 4, 2001, at 17:52:19

In reply to moclobemide and desyred URGENT please, posted by Sigolene on February 3, 2001, at 1:11:15

> Has someone already taken together 25 or 50 mg desyred and 300 mb moclobémide (manerix, aurorix) ?
> it's supposed to be countaindicated but i can't sleep with moclobémide and i WANT to try it.
>
> Sigolène


Hi there, cutie.

It is common practice to use Desyrel (trazodone) as a sleep aid when combined with an MAO inhibitor. Of course, there might also be the added benefit of producing a more robust antidepressant effect. I assume from your use of such a low dosage of Desyrel that it is for sleep.

Joffe and his colleagues have advocated using moclobemide in combination with SSRIs in treatment resistant cases. I don't doubt that they have been successful and without serious side effects; the one most significantly dangerous being serotonin syndrome. However, there have been quite a few reports of serotonin syndrome developing with such combinations. Since Desyrel does inhibit the reuptake of serotonin to a significant degree, using it in combination with any MAOI should be monitored for the development of serotonin syndrome. In clinical practice, such an event with desyrel is probably rare.

I would say that combining moclobemide with Desyrel would be very safe.


- Scott

 

Re: moclobemide and desyred URGENT please

Posted by Chocoholic on February 18, 2001, at 13:23:23

In reply to moclobemide and desyred URGENT please, posted by Sigolene on February 3, 2001, at 1:11:15

Hi, Sigolene.
I have been taking moclobemide for 4 years and have taken various things for sleep (I have a sleep problem even when not on moclobemide).
Benzodiazepines work well, as does Neurontin. > Has someone already taken together 25 or 50 mg desyred and 300 mb moclobémide (manerix, aurorix) ?
> it's supposed to be countaindicated but i can't sleep with moclobémide and i WANT to try it.
>
> Sigolène


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