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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 6 of 6. This is the beginning of the thread.
Posted by SaM on October 22, 1998, at 2:44:51
Has anyone experienced side effects on olanzapine such as white blood count drop or NMS. Would appreciate any dialogue in this area.Sam
Posted by Debbie on January 16, 1999, at 13:37:50
In reply to Olanzapine and side effects, posted by SaM on October 22, 1998, at 2:44:51
>
> Has anyone experienced side effects on olanzapine such as white blood count drop or NMS. Would appreciate any dialogue in this area.
> Sam
Has anyone experienced weight gain on olanzapine that doesn't respond to dieting.
Posted by David K. on January 17, 1999, at 6:09:31
In reply to Re: Olanzapine and side effects, posted by Debbie on January 16, 1999, at 13:37:50
I experienced some weight gain that I believe Olanzapine was responsible for. It also increased my appetite. But dieting/starving didn't seem to help it at all.
The strangest side effect I had from it, though, was Carpal Tunnel Syndrome! After I started taking the Zyprexa, I felt a tingling in my fingertips. My doctor convinced me that it was probably REAL Carpal Tunnel Syndrome (which was, actually, pretty likely.) It got so bad that I was wearing a wrist support at work.
Then I stopped the Zyprexa, and it all went away.
Bizarre.
Posted by douglas Berryman on May 4, 1999, at 8:59:39
In reply to Re: Olanzapine and side effects, posted by douglas berryman on May 4, 1999, at 8:49:07
my brother has been diagnosed with schizoaffective disorder. He has been for a number of years been taking psychotropic medications and lithium. Currently, he is taking olzanpine, lithium, divalproex (depakote). I have noticed lately that he is displaying psuedo-parkinsonism like symptoms. At times he has difficulty not spilling a glass of water. Is a side effect of olanzapine tardivdiskinsea or psuedo-parkinsonism? I suspect it has a contributory effect after 10 years+ of taking psychotropic medication. It just concerns me because it seems to have become more noticable at what I perceive at a alarming rate. I wonder what can be done to help alleviate this horrible side effect. Change medication? I know that the side effects are more or less permanent. But, again, is there a way to help alleviate or reduce the psuedo-parkinsonism?
Posted by Jimmy D on May 30, 1999, at 23:01:55
In reply to Re: Olanzapine and side effects, posted by douglas Berryman on May 4, 1999, at 8:59:39
My wife has suffered from side effects on these Neuroleptics Drugs. There is a TD syndrome that has a very high risk and risk increases the longer a patient is on these drugs.
http://www.breggin.com/neuroleptics.html
Tardive Dyskinesia: Tardive dyskinesia (TD) a syndrome consisting of potentially irreversible involuntary dyskinetic movements, is associated with the use of antipsychotic drugs. Tardive dyskinesia occurs more frequently in elderly patients, however, patients of any age can be affected. It is unknown whether antipsychotic drugs may differ in their potential to cause TD. However, during long-term, double-blind extension maintenance trials (R94 olanzapine-treated patients; median olanzapine treatment 237 days), olanzapine was associated with a statistically significantly lower incidence of treatment emergent dyskinesia compared to haloperidol.
The risk of developing tardive dyskinesia and the chance of it becoming irreversible, are believed to increase as the duration of treatment and the cumulative dose of antipsychotic drugs increase. However, the syndrome can develop, although less commonly, after relatively brief periods of treatment at low doses. There is no known treatment for established cases of TD. The syndrome may remit, partially or completely, if antipsychotic drug treatment is withdrawn. Antipsychotic drug treatment itself, however, may suppress the signs and symptoms of tardive dyskinesia thereby masking the underlying process.
Given these considerations, olanzapine should be prescribed in a manner that is most likely to minimize the risk of tardive dyskinesia. As with any antipsychotic drug, olanzapine should be reserved for patients who appear to be receiving substantial benefit from the drug. In such patients the lowest effective dose and the shortest duration of treatment should be sought. The need for continued treatment should be reassessed periodically.
If signs or symptoms of tardive dyskinesia appear in a patient on olanzapine, drug discontinuation should be considered. However, some patients may benefit from continued treatment with olanzapine despite the presence of the syndrome.
Posted by Deborah R. on August 21, 1999, at 7:33:25
In reply to Olanzapine and side effects, posted by SaM on October 22, 1998, at 2:44:51
>
> Has anyone experienced side effects on olanzapine such as white blood count drop or NMS. Would appreciate any dialogue in this area.
> Sam
Dear Sam - I wish I had found your post earlier - I hadnt had time to do a complete search. My Mum was hospitalised for 4 weeks with all the symptoms of NMS - this came on dramatically about 4 weeks after switching from Risperidone to Olanzapine - dosage was 17.5mg, Mum now home and better, still on Olanzapine though - 7.5mg and still with some symptoms. I am concerned for her, have you or a loved one experienced something similar. I know this is a long shot as your post is from last year, but you never know. Kind regards, hope you read this and are able to respond.Deb. R.
This is the end of the thread.
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