Psycho-Babble Alternative Thread 1103507

Shown: posts 1 to 6 of 6. This is the beginning of the thread.

 

LDN and ULDN

Posted by Hugh on March 6, 2019, at 11:17:49

Low-dose naltrexone (LDN) is used to treat some forms of cancer and some autoimmune diseases, such as MS, rheumatoid arthritis, ulcerative colitis, Crohn's, and lupus. Some people find it helpful for depression and bipolar disorder.

Naltrexone was approved by the FDA in 1984 to treat addictions to opioids and alcohol. Naltrexone tablets are 50 mg. LDN is usually taken in doses of 1.5 to 4.5 mg.

http://www.lowdosenaltrexone.org/

https://sites.google.com/site/dudleyslowdosenaltrexonesites/

Taken at doses much lower than 1.5 mg, naltrexone could be even more effective as an antidepressant. Ultra-low-dose naltrexone (ULDN) doses are in the micrograms, nanograms, and even the picograms. At these extremely low doses, naltrexone activates the opioid receptors in the brain.

The following quote is from

https://www.researchgate.net/publication/226113151_Ultra-Low-Dose_Naltrexone_Decreases_Dependence_and_Addictive_Properties_of_Opioids

"Cotreatment with ultra-low-dose naltrexone at 16.7, 20, or 25 ng/kg, but not at 10 or 200 ng/kg, induced a significant CPP after this 2-h delay. This finding implies that, whereas the rewarding effects of morphine have dissipated by 120 min postinjection, ultra-low-dose naltrexone may extend this effect."

In other words, an extremely low dose of naltrexone enhanced the effects of morphine, and prevented tolerance to it from developing. And it prevented dependence and addiction from developing. A higher, but still tiny, dose of naltrexone didn't have these beneficial effects.

Even if you're not taking opiates, you might benefit from taking ultra-low-dose naltrexone, since we all have naturally occurring opioids -- endorphins. An extremely low dose of naltrexone, taken every day, might improve your brain's response to your naturally occurring endorphins.

So if you aren't helped by 1.5 to 4.5 milligrams of naltrexone, try lowering your dose to micrograms. If that doesn't help, lower your dose to nanograms. If that doesn't help, lower it to picograms. Other than the naltrexone, all you need is distilled water to dilute it with and a calculator.

Naltrexone is water-soluble, so dissolve a 50-mg tablet in 50 ml of distilled water and use a medicine dropper to measure the dose. If refrigerated, liquid low-dose naltrexone will keep for several weeks.

 

Re: LDN and ULDN Hugh

Posted by beckett2 on March 6, 2019, at 13:42:53

In reply to LDN and ULDN, posted by Hugh on March 6, 2019, at 11:17:49

Here's a long thread from the archives. I imagine there's more>

http://www.dr-bob.org/cgi-bin/pb/mget.pl?init=/babble/20091001/msgs/919880.html

 

Re: LDN and ULDN beckett2

Posted by Hugh on March 6, 2019, at 20:39:31

In reply to Re: LDN and ULDN Hugh, posted by beckett2 on March 6, 2019, at 13:42:53

Thanks. I hadn't seen that. Bleauberry and Phillipa from 2009. Interesting to see that Dr. Bob was posting back then.

> Here's a long thread from the archives. I imagine there's more>
>
> http://www.dr-bob.org/cgi-bin/pb/mget.pl?init=/babble/20091001/msgs/919880.html
>
>

 

Re: LDN and ULDN

Posted by Lamdage22 on March 17, 2019, at 16:17:15

In reply to LDN and ULDN, posted by Hugh on March 6, 2019, at 11:17:49

I took it for two weeks but then got scared it might make me worse! Currently, I am trying NAC. And Iron. Ferritin = currently 29

 

Re: LDN and ULDN Lamdage22

Posted by Hugh on March 18, 2019, at 14:37:15

In reply to Re: LDN and ULDN, posted by Lamdage22 on March 17, 2019, at 16:17:15

As I recall, the low dose of LDN that you were on initially made you feel better. When you increased your dose, you felt worse. Did you try going back to a lower dose before you quit?

 

Re: LDN and ULDN

Posted by Lamdage22 on March 21, 2019, at 6:15:42

In reply to Re: LDN and ULDN Lamdage22, posted by Hugh on March 18, 2019, at 14:37:15

I already quit. id have to restart. I want to see how far more Iron will get me.


This is the end of the thread.


Show another thread

URL of post in thread:


Psycho-Babble Alternative | Extras | FAQ


[dr. bob] Dr. Bob is Robert Hsiung, MD, bob@dr-bob.org

Script revised: February 4, 2008
URL: http://www.dr-bob.org/cgi-bin/pb/mget.pl
Copyright 2006-17 Robert Hsiung.
Owned and operated by Dr. Bob LLC and not the University of Chicago.