Psycho-Babble Medication Thread 491759

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Buspar helpful for OCD?

Posted by chess on April 30, 2005, at 0:01:48

my psy doc suggested Buspar to help with my OCD, but I've never heard if Buspar helps or makes OCD worse.
Anyone know?
I'm on Lexapro 20mg right now

Re: Buspar helpful for OCD?

Posted by BIGDaddyachmed69 on April 30, 2005, at 0:09:09

In reply to Buspar helpful for OCD?, posted by chess on April 30, 2005, at 0:01:48

> my psy doc suggested Buspar to help with my OCD, but I've never heard if Buspar helps or makes OCD worse.
> Anyone know?
> I'm on Lexapro 20mg right now
>

I HAVE heard that Buspar is sometimes used in combination with an SSRI to treat refractory OCD.

Re: Buspar helpful for OCD?

Posted by linkadge on April 30, 2005, at 8:52:54

In reply to Re: Buspar helpful for OCD?, posted by BIGDaddyachmed69 on April 30, 2005, at 0:09:09

Generally not but sometimes helpful for certain symptoms of OCD ie anxiety.

The therapudic action of SSRI's in OCD is thought to be through activation of second-messanger cascades through agonism at the 5-ht2a,c receptors.

Infact hallucinogens like mescaline which are potent agonists of the 5-ht2 system, have been studied for clues into the illness.

Buspar preferentially agonises the 5-ht1a receptor which is responsable for antianxity effect, but does not seem to have direct anti-obsessional qualities.

Linkadge

Re: Buspar helpful for OCD?

Posted by Phillipa on April 30, 2005, at 19:37:07

In reply to Re: Buspar helpful for OCD?, posted by linkadge on April 30, 2005, at 8:52:54

I was given buspar when my anxiety was uncontrollable. I never noticed a thing. I'd never considered that my pdoc at the time thought my high anxiety was related to OCD, although I am compulsive and do a lot of ruminating and counting. Fondly, Phillipa

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