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Re: nortriptyline+sertraline+methylphendate SLS

Posted by undopaminergic on September 5, 2023, at 2:19:54

In reply to Re: nortriptyline+sertraline+methylphendate gman22, posted by SLS on September 4, 2023, at 17:54:20

> > Looking for feedback on this as a possible combination...Or if I take just two of them, which ones would be the best and safest to take long term.
> > Thanks
> I can't speak to the benefits of taking methyphenidate to produce a true antidepressant effect, even when used in combination with other medications. It most often gives someone more mental energy, but that seems to be more of a palliative measure than a therapeutic one. Have you read or heard of methylphenidate producing a true remission? I just haven"t personally seen miracles with it. If it helps palliatively onle, it makes sense to use it until you find an effective antidepressive treatment.

I'm not sure how you differentiate palliative and therapeutic.

Methylphenidate (and the like) produces a fast response. The difference between without it and with it was like night and day in my case. It helped for energy, and against apathy (including poverty of thought) and suicidal ideation, within minutes of its administration. Typically, it helps only for as long as one takes it, but I've sometimes seen the effects linger.

Although I wrote that the contrast between not using it and doing so was like night and day for me, it did not produce full remission.





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