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Re:Neuroleptics brain specific antihistaminergic? undopaminergic

Posted by Jay2112 on February 14, 2023, at 23:46:19

In reply to Re:Neuroleptics brain specific antihistaminergic? Jay2112, posted by undopaminergic on February 12, 2023, at 12:00:25


> > I took betahistine for almost 3 months (I am in Canada). It seemed to make me very depressed. I was taking it for inner-ear problems.
> >
> > Jay
>
> H3 antagonists increase histaminergic neurotransmission, and should have stimulant-like effects. Maybe you have endogenously high histamine? Do you benefit from regular (H1) antihistamines?
>
> -undopaminergic
>

This was a few years ago, so I am a bit unsure. I believe at first, it really helped my stomach. I do find some antihistamines, like benadryl, very helpful at times when I just can't settle down. But, I currently take testosterone/folic acid/B12/and vit E, which is supposed to increase histamine. At first it bothered me, lots of itch, but now I am much more used of it. I have methoprazine as a power histamine antagonist. And I take 15mg of mirtazapine, and amitriptyline when needed. Surprisingly, methoprazine works better than chlorpromazine, for me, esp with stomach issues.

Jay


Humans punish themselves endlessly
for not being what they believe they should be.
-Don Miguel Ruiz-


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poster:Jay2112 thread:1121718
URL: http://www.dr-bob.org/babble/20230117/msgs/1121785.html