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Re: Extensive review on Lithium Orotate.

Posted by SLS on January 15, 2023, at 11:51:38

In reply to Extensive review on Lithium Orotate., posted by undopaminergic on January 15, 2023, at 10:58:13

> Hi all,
> I just finished reading this extensive review on lithium orotate, with a focus especially on a comparison with lithium carbonate, although all lithium salts with a history of use are considered in brief. The role of orotic acid as a mineral carrier in general is also considered in depth.
> "Lithium orotate: A superior option for lithium therapy?"
> The link leads to the abstract, and offers further links to the freely available full text article.
> All in all, I'd say this is as good as it gets without further original research.
> -undopaminergic

I don't like what these authors did. They provide no clinically relevant information. Everything they write about is theoretical.

In the abstract that you provided the linked to, there is nothing referring to measured clinical activity.



"LiOr is proposed to cross the blood-brain barrier and enter cells more readily than Li2 CO3 "


No clinical applicability:

"While no clinical trials for the use of LiOr in BD have been conducted..."


Closing remarks:

"There is one certainty regarding the future of LiOr in psychiatric applications: more research is needed."


No dice.

I remember a hoard of Psycho-Babblers rushing out to buy lithium orotate some 15 or more years ago. Lots of takers. No benefits.

I'm sure by now, you have seen me tout the utility of using low-dosage lithium therapy to treat depression. At the dosages necessary for this treatment to work, there is very little risk of kidney and thyroid damage. The effects of lithium on these two organs are dosage-dependent. I have been taking lithium at a dosaage of 300 mg/day for about 10 years. My kidney enzymes and thyroid levels remain normal as of 6 months ago.

- Scott

Some see things as they are and ask why.
I dream of things that never were and ask why not.

The only thing necessary for the triumph of evil is that good men do nothing.




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