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Re: mood stablizers

Posted by SLS on March 6, 2021, at 11:52:30

In reply to Re: mood stablizers, posted by undopaminergic on February 24, 2021, at 2:02:27

> >
> > does anyone know if mood stablizer can be used for depression alone?
> Yes, for a lot of psychiatrists that is the first option for bipolar disorder.
> -undopaminergic

Maybe Lamictal (lamotrigine). My guess is that it increases dopamine activity in the nucleus accumbens via disinhibition facilitated by a reduction of glutamate release in the thalamus. There may be other structures involved as well.

I would like to mention that an apparently unipolar depression can still have a bipolar diathesis. This alone warrants a trial of a mood stabilizer when antidepressants alone do not have much, if any, appreciable effect.

Oxcarbazepine, tiagabine, and lamotrigine would my picks.

- Scott

Some see things as they are and ask why.
I dream of things that never were and ask why not.

The only thing necessary for the triumph of evil is that good men do nothing.




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