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Re: Luvox fatigue is too much to bear. former poster

Posted by chumbawumba on January 12, 2017, at 18:29:57

In reply to Luvox fatigue is too much to bear., posted by former poster on September 29, 2016, at 14:13:13

> Sorry I haven't posted for awhile. My last post was about Dopa Mucuna which seemed to have lost its effectiveness after about 1 month. I've been on fluvoxamine for about a year. It's effective for the symptoms I'm taking it for but at a cost. All day long I want to lay down and sleep. This urge is present in my mind 90% of the day. Dr. gave me Vyvanse 70mg. but it seems to have little effect and lasts about 4 hours then I'm back to dragging through the day. I've taken Vyvanse with other SSRI's with good results but with Fluvoxamine seems like it blocks the motivating action of Vyvanse.
> Any thoughts, suggestions?

The fact that you had a partial response to L-Dopa is a clue. I'm not sure where it leads but it's a clue.

Interesting that Vyvanse was not effective with your SSRI. I've taken it with Prozac and it was very effective. Luvox seems to be unique in that it is an agonist at the sigma-1 receptor. The significance of that is mysterious. But the uniqueness of Luvox in it's binding affinity there may be why you are having an atypical response to stimulants. You could try a more selective SSRI like Lexapro. Which isn't mucking around with mysterious receptors. But it's always a little dicey, switching drugs. Finding one that works well for you is pretty great. So you do want to hold onto that if you can.

Provigil is generic now and is a dopamine reuptake inhibitor. I have taken in combination with both Prozac and Parnate. I find it stimulating without the jitteriness of Ritalin or Amphetamine. It lasts a long time and doesn't produce euphoria so it's got low abuse potential. You can take up to 600 mg which I have done. At that dose your eyelids should be stapled to your forehead. The military uses it for pilots flying transoceanic missions.




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