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Re: Ketamine infusions for Depression

Posted by Edward807 on January 4, 2017, at 10:08:03

In reply to Re: Ketamine infusions for Depression chumbawumba, posted by SLS on January 4, 2017, at 6:39:31

> > > The dosage of ketamine is critical - (0.5 mg/kg) over 40 minutes. You can have IV infusions every day, but if the dosage is too low - or too high - it won't work for depression.
> > >
> >
> > Why do so many docs use intranaasal ketamine or intramuscular shots? One could deliver the correct dosage but timing smooth delivery over 40 minutes would be impossible. Is the rate critical, the dosage critical or both?
> It is critical. Taking too much ketamine ruins the effect. Intranasal ketamine can be regulated by changing and titrating the dosage. However, there are people who do not respond to intranasal who do go on to respond to infusions.
> A major question is, would someone want to commit the rest of their life to going for infusions every few days to a week rather than sniff a liquid for a few seconds every 1-5 days? Try intranasal first, then go for infusions if necessary. That would be my answer to the question.
> - Scott

I've had five infusions and am taking sublinqual ketamine (troches) for maintenance. The dosages for the infusion varied, it's not one size fits all. Both produce an almost immediate antidepressant effect. It remains to be seen if it is sustainable. The infusions produced a self reflective inner experience that's hard to describe. Journaling my impressions and working with a therapist was indispensable.




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