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Re: Why an SNRI for anxiety?

Posted by linkadge on December 2, 2016, at 16:27:56

In reply to Re: Why an SNRI for anxiety? linkadge, posted by Prefect on November 29, 2016, at 6:55:38

Effexor alone does cause some sleep disruption (for me). I too am thin and fit, but have had frequent sleep problems. Mind you, all antidepressants (except perhaps amitriptyline and mirtazapine) have caused sleep disruption for me. Amitriptyline is also an SNRI (much more potent on norepinephrine than Effexor). I don't get the sleep disruption on amitriptyline, perhaps because of its antihistamine / 5-ht2 antagonism. Actually, I get less sleep disruption on Effexor than I did on citalopram.

Effexor is mostly an SSRI in low doses. However, in my opinion it feels much different from an SSRI even in low doses, which (to me) suggests there are additional targets of Effexor that don't show up on paper. According to pubmed articles, it appears to have some significant effect on inflammation and the immune system.

By keeping the dose of Effexor low, and taking mirtazapine, when needed, I have minimized sleep disruption.

I take other supplements (magnesium and niacin) which help sleep.

As far as ginger root, I drink it in tea form. I get organic ginger root tea bags. I get more effect if I let them steep. Usually, I take this 3-4 times a week; more so, if I am under more stress. I have also taken it in capsule form, which works.





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