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Re: Why an SNRI for anxiety?

Posted by linkadge on November 23, 2016, at 20:34:14

In reply to Re: Why an SNRI for anxiety? rjlockhart37, posted by Prefect on November 23, 2016, at 20:14:34

Pristiq and Effexor mainly affect serotonin.

Effexor (for me) is very good for anxiety, especially in lower doses.

Effexor has some significant anti-inflammatory effects, which may be behind its improvement in mood and anxiety. In addition, raising serotonin and norepinephrine can antagonize acetylcholine. Acetylcholine excess can cause anxiety.

Norepinephrine can cause anxiety (when released excessively), but it can also help initiate adaptive responses to stress (i.e. reducing avoidance behavior, and possibly improving cognitive engagement).





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