Psycho-Babble Medication | about biological treatments | Framed
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Re: Acetylcholine - Any new developments?

Posted by dcruik518 on August 22, 2008, at 10:14:53

In reply to Re: Acetylcholine - Any new developments?, posted by dcruik518 on August 22, 2008, at 10:04:41

Benapryzine, benzhexol, orphenadrine, and bornaprine are other examples of anticholinergic drugs used alone or in combination with other medications in Parkinson's disease to improve motor function. Disturbances in dopaminergic transmissions are associated with the symptoms observed in Parkinson's disease. The beneficial effects of anticholinergics in this disease are due to the resulting imbalance between dopamine and acetylcholine ratio in neurons. These anticholinergic agents may decrease gastrointestinal movements, causing constipation; and the positive effects on motor functions vary among patients. Other classes of drugs available today that act on the pathways of dopamine and its receptors to treat Parkinson's disease, such as levodopa, tolcapone, and pramipexol, effectively increase the levels of dopamine at dopaminergic receptors in neurons.




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