Psycho-Babble Medication | about biological treatments | Framed
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Re: one thing Prozac does, not chemical imbalance

Posted by SLS on May 27, 2006, at 10:06:23

In reply to one thing Prozac does, not chemical imbalance, posted by Larry Hoover on May 27, 2006, at 8:59:53

> It's not in Pubmed yet.
> Lar

I wish they were more specific regarding the chain of events leading up to the production of these progenitor cells. Does the drug bind to a cytosolic protein or a nucleic gene regulator, or is it the result of repeated action potentials produced by the 5-HT reuptake inhibition? In other words, is this neural generation an effect secondary to the resolution of depression or is it the primary resolution of the depression itself?

I'm not expressing myself very well. Some of the verbiage in the article hints that the proliferation of cells seen in the dentate gyrus is the result of increased electrical activity. This by itself explains nothing. It is more of an observed consequence of exposure to Prozac rather than an explanation for the cascade of events leading up to it.

"If a drug fosters electrical activity in the brain, that tells the brain that things are happening and that it might be good to make new neurons to deal with activity."

I wish we could read the full text of the article to be published.

- Scott




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