Psycho-Babble Medication | about biological treatments | Framed
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Tolerance reversal.

Posted by Questionmark on March 14, 2004, at 2:05:23

In reply to Tolerance reversal., posted by Questionmark on March 7, 2004, at 7:56:08

(i'm re-posting this, as i only got one response):
Two questions, related to treatment of antidepressant poop-out:
1) How/why in the world are opioid antagonists (e.g. naltrexone) possibly beneficial for antidepressant poop-out? Wouldn't these just make one more dysphoric, regardless of whether or not s/he was on an antidepressant (opioid agonist or not)?? How in the world does this work?

2.a.) Which do you think would be best for antidepressant poop-out (and which for which types of antidepressants, if they differ on this): (A) Opioid antagonist, (B) NMDA antagonist, or (C) lithium?
2.b.) Why?

Linkadge replied...
"I have heard of great sucess with inositol which helps resensitize the serotonin receptors.
Thanks Linkadge. That's quite encouraging, since i'm on Nardil, a very serotonergic drug. But i'm still somewhat wary of inositol now-- and not extremely confident in it, since i tried it before and only noticed bad gas and diarrhea.




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