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Re: What about Klonopin, Depakote and GABA... Janelle

Posted by fachad on May 6, 2002, at 21:59:46

In reply to What about Klonopin, Depakote and GABA..., posted by Janelle on May 6, 2002, at 4:46:05

My knowledge is very limited here, but I'll try put out a vauge answer for you.

Klonopin directly activates GABA receptors. It is a real benzodiazapine and is a direct agonist at the benzodiazapine/GABA receptor.

Depokate somehow (?) "enhances" GABA activity, but it is not thru a direct agonist activity like Klonopin.

That's all I know.

> I have read that Klonopin and Depakote both work on GABA, but apparently in different ways. I don't understand how each of these meds works on GABA and would very much appreciate it if anyone who knows how they each affect GABA could explain it briefly and as simply as possible. Thank you!




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