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Re: What about Klonopin, Depakote and GABA... Janelle

Posted by Ritch on May 6, 2002, at 13:31:00

In reply to What about Klonopin, Depakote and GABA..., posted by Janelle on May 6, 2002, at 4:46:05

> I have read that Klonopin and Depakote both work on GABA, but apparently in different ways. I don't understand how each of these meds works on GABA and would very much appreciate it if anyone who knows how they each affect GABA could explain it briefly and as simply as possible. Thank you!


All I know about the differences between Klonopin's and Depakote's effect on GABA is that Klonopin acts at the GABA receptors (like other benzos), whereas from what I understand, Depakote tends to promote GABA synthesis (your brain makes more of it). There are others here that know more specifics, but that's what I understand it to be.

hope this helps,





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