Psycho-Babble Medication | about biological treatments | Framed
This thread | Show all | Post follow-up | Start new thread | List of forums | Search | FAQ

Re: Which benzo is *least* sedating? +other stuff Elizabeth

Posted by Mitch on October 31, 2001, at 23:28:28

In reply to Re: Which benzo is *least* sedating? +other stuff Mitch, posted by Elizabeth on October 31, 2001, at 22:26:49

> > I have found that cheap old generic chlordiazepoxide (Librium) was the least sedating benzo that I have ever taken.
>
> I didn't experience any sedation on Librium. I've been interested in finding out whether I could take a high dose of it for panic disorder (I had already been taking quite a bit -- 50 mg q.i.d. -- when I gave up on it, but I probably could have gone higher without any problems). But there's little evidence supporting the use of low-potency benzos in PD.

Wow! I used to get by OK on 10mg tid! Of course, I am med sensitive and it generally takes about 1/6 to 1/3 of anything to do the same thing for me that it takes for other folks. It is true that the low-potency benzos work better for GAD symptoms. The Klonopin I take will prevent a panic attack, but at the cost of amblyopia, cognitive dysfunction, etc. ChlorD. would prevent a panic attack for me *most* of the time-but it wasn't *reliably* effective. The ChlorD. was also a lot less depressogenic (?) than Valium.

>
> > I also have IBS/d and I never have heard of "celiac disease" before. I know what you mean by "hellish AD's"!! I get the most benefit from SSri's, but they DO rip my guts to shreds. I have tried adding nortriptyline (20-30mg/day) to the SSRi and it did help a lot, BUT I didn't like the sfx from the NT!
>
> What side effects did NT have that bothered you?

Mainly cold extremities (cold nose/hands, ie.), also got some facial numbness on the front of my face and forehead (that was like high-dose Gabitril in some ways). Also, my arms and legs would go to sleep easily and get numb and tingle. A little bit of tachycardia as well.

>
> (BTW, what did you mean by "IBS/d?")

Diarrhea predominant IBS. If I add the NT to an SSRi it tends to dampen that problem (anticholinergic effects). Remeron worked even better for that (IBS/d)-I believe because of the 5-HT3 antagonism. But it hits far more receptors than the NT did! Definitely the NT was less antihistaminic and I didn't get irritable on it (no alpha-2 antagonism).

BTW, I am thinking about starting a thread regarding Odansentron (ZOFRAN). It is a selective 5-HT3 antagonist which is used for chemotherapy/radiotherapy/postsurgical nausea and vomiting from the chemo drugs or from anesthetics/opioids. I heard somewhere that it decreased alcohol cravings in some people dramatically-also if my theory is correct it should be able to reduce nausea/diarrhea from SSRI's as well. I haven't brought it up to my pdoc just yet. I was given Odansentron immediately after my thyroid surgery and I was sitting up in bed shortly after +morphine and eating a big tray of food with no nausea!

>
> -elizabeth


Share
Tweet  

Thread

 

Post a new follow-up

Your message only Include above post


Notify the administrators

They will then review this post with the posting guidelines in mind.

To contact them about something other than this post, please use this form instead.

 

Start a new thread

 
Google
dr-bob.org www
Search options and examples
[amazon] for
in

This thread | Show all | Post follow-up | Start new thread | FAQ
Psycho-Babble Medication | Framed

poster:Mitch thread:82248
URL: http://www.dr-bob.org/babble/20011025/msgs/82815.html