Dr. Bob's Psychopharmacology Tips

Urinary incontinence from fluoxetine

Date: 06 Jan 96 10:13:57 EST
From: cynthia sortwell <102574.1227@compuserve.com>
Subject: Urinary incontinence from fluoxetine

A female pt in her 30s with OCD who had benefited from Prozac developed urinary incontinence when the dose was increased to 40 mg qam. Bethanechol 20 mg tid was a help but she began to develop headaches.

Date: Sat, 6 Jan 1996 16:32:15 -0800 (PST)
From: "Mark I. Levy" <milevy@itsa.ucsf.EDU>
Subject: Urinary incontinence from fluoxetine

I've seen urinary incontinence and cystitis in women on fluoxetine a number of times. It must be a result of autonomic effects on sphincter control. I've had some improvement, for reasons I do not understand, with reducing fluoxetine and adding paroxetine, e.g. 20 mg fluoxetine and 20 mg paroxetine instead of 40 mg fluoxetine.

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