Dr. Bob's Psychopharmacology Tips

Trazodone meta-analysis

Date: Wed, 21 Jun 1995 21:18:20 -0400 (EDT)
From: Bill Boyer <wboyer@emory.edu>
Subject: Trazodone meta-analysis

I thought I'd bring people up to date on the Trazodone meta-analysis I wrote about a month or so ago.

Bottomline: Data from the 16 studies reviewed showed that trazodone was associated with (global) response in 58.8% and control antidepressants in 66%. This difference was highly statistically significant due to the large number of patients involved (N=1704). Average trazodone dose, dose schedule (hs vs split dose), in or outpatient status, diagnostic criteria (DSM-III, RDC, or Feighner vs Other) and type of control antidepressant (tri- or tetra-cyclic vs Other) did not make a significant difference.

By posting this I hope to encourage others to write about their new research findings. The net won't replace journals anytime soon, but its immediacy and two-way nature haven't been exploited nearly enough in our field.

This topic is indexed under the following subjects:

URL: http://www.dr-bob.org/tips/split/Trazodone-meta-analysis.html
Original tips copyright 1994-97 original authors.
Web page copyright 1995-97 Robert Hsiung.