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Date: Tue, 16 Jul 1996 00:53:54 -0500 (EST)
From: "Charles Hart Enzer, M.D." <Charles.Enzer@UC.Edu>
Subject: Subcutaneous haloperidol decanoate
Develop a working alliance...
Date: Tue, 16 Jul 1996 20:20:07 -0700 (PDT)
From: steven freedman <sff@itsa.ucsf.edu>
Subject: Subcutaneous haloperidol decanoate
Being a person who gives haloperidol decanoate injections fairly regularly, I can't imagine getting it [to go] through an insulin syringe.
Date: Wed, 17 Jul 1996 18:01:53 -0500 (EST)
From: "Charles Hart Enzer, M.D." <Charles.Enzer@UC.Edu>
Subject: Subcutaneous haloperidol decanoate
Try it, the patient will like it. It is less humiliating than the buttocks. And even less humiliating to self-administer.
Date: Wed, 20 Nov 1996 17:24:45 -0500 (EST)
From: "Charles Hart Enzer, M.D." <Charles.Enzer@UC.Edu>
Subject: Subcutaneous haloperidol decanoate
On Wed, 20 Nov 1996, Myron L. Pulier wrote:
Somehow I recall that subcutaneous refers to inserting a thin needle just under the epidermis and creating a little bleb. This would not accommodate the volume of fluid...The above is an intradermal injection.
Subcutaneous is Below the skin and Above the muscle.
I give my patients (behind the triceps) or instruct them to give themselves (in the abdomen) every 3-4 weeks 20-45 "units" (0.20-0.45 cc) with an Insuline U-100 28-29 gauge 1/2 inch needle.
Additionally, I teach them early signs of recurrence and how to medicate with Trilafon (perphenazine) 2-8 mg or with Moban (molindone).
Gradually, the patients have gone into remission, returned to school, and graduated. All but one have become licensed health professionals.
Once in remission, we meet monthly.
I'm availible 24 hours a day, 7 days a week for emergencies.
Date: Thu, 21 Nov 1996 01:58:30 -0500 (EST)
From: "Charles Hart Enzer, M.D." <Charles.Enzer@UC.Edu>
Subject: Subcutaneous depot antipsychotics
On Wed, 20 Nov 1996, Larry Ereshefsky wrote:
The guru on depot subQ is Dr. Bill Glazer... he has had a lot of experience with this...I've been doing this since the early 80s. I learned it at the APA in LA from Larry Kane who decribed the English as doing it.
When Bill was in Cincinnati a few years ago, he said he hadn't heard of it.
Key points:
Date: Mon, 25 Nov 1996 22:58:17 -0600
From: Larry Ereshefsky <Ereshefsky@uthscsa.edu>
Subject: Subcutaneous depot antipsychotics
At 10:38 -0500 11/21/96, Alex Cardoni wrote:
See Glazer et al., J. Clin Psychiat 1987; 48: 237-39. "Injection Site Leakage of Depot Neuroleptics: Intramuscular versus Subcutaneous Injection"One issue regarding subQ. No one to my knowledge has done any type of formal PK study regarding bioavailability. The clinical data from Glazer's experiences is quite positive, but with a time to steady state of 4 months, the chage in drug delivery would only slowly become clinically apparent.
This topic is indexed under the following subjects:
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Dr. Bob is Robert Hsiung, MD,
dr-bob@uchicago.edu
URL: http://www.dr-bob.org/tips/split/Subq-depot-antipsychotics.html
Original tips copyright 1994-97 original authors.
Web page copyright 1995-97 Robert Hsiung.