Psycho-Babble Neurotransmitters Thread 965510

Shown: posts 1 to 17 of 17. This is the beginning of the thread.

 

Serotonin Can Someone Explain the Gut Connection m

Posted by Phillipa on October 12, 2010, at 14:21:17

Okay finding out just how stupid I am. And Serotonin is just one topic. Now if they are saying too much serotonin in the gut causes bad bones. Why do we take SSRI's. As I see a lot of complaints of stomach, intestinal problems. I don't get them so does it have a thing to do with the brain. Totally confused. Well there has to be some type of connection so if any bad bones don't take is that true or false and what's the connection. Phillipa ps no knowledge is good, a little is dangerous, and then more is better guessing

 

Re: Serotonin Can Someone Explain the Gut Connection

Posted by ed_uk2010 on October 12, 2010, at 14:21:18

In reply to Serotonin Can Someone Explain the Gut Connection m, posted by Phillipa on October 9, 2010, at 13:16:42

>Now if they are saying too much serotonin in the gut causes bad bones.

Serotonin has numerous roles in the body. In the brain, serotonin acts as a neurotransmitter and regulates mood, sleep and appetite, amongst other things. Serotonin is also produced in the small intestine (in the duodenum). It is synthesised from the amino acid tryptophan which comes from the proteins in our food. Serotonin produced in the intestine is a seperate issue to the serotonin produced in the brain, they do not mix.

In the intestine, serotonin appears to affect gut motility (intestinal contractions). Some of the serotonin from the gut travels around the body in the bloodstream - inside platelets. Platelets require serotonin to allow them to stick together when the blood clots.

Serotonin also acts as a hormone; it acts on the cells of the skeleton and 'tells' them to slow the production of new bone. An experimental drug which blocks the formation of serotonin in the intestine may turn out to be a useful treatment for osteoporosis in humans. It has been shown to strengthen the bones of mice. Because the drug causes less serotonin to be released by the intestine into the blood, there is less serotonin to bind to bones and cause them to become weaker.

>Why do we take SSRIs. As I see a lot of complaints of stomach, intestinal problems. I don't get them so does it have a thing to do with the brain.

SSRIs do not cause more serotonin to be produced by the body, but they do modulate the effects of serotonin. All drugs can cause side effects. SSRIs can cause psychiatric side effects and gastro-intestinal side effects. They also increase the risk of abnormal bleeding, particularly gastic bleeding. This could be because they reduce platelet function.

There is some evidence that SSRIs reduce the formation of bone, and may reduce bone mineral density. The risk of fractures appears to be increased by long term use of SSRIs.

SSRIs can be beneficial in numerous conditions, notably depression and OCD. Appropriate use of medication involves balancing the risks with the benefits. You have to decide whether or not the benefits outweigh the risks for each individual patient.

 

Re: Serotonin Can Someone Explain the Gut Connection ed_uk2010

Posted by Maxime on October 12, 2010, at 14:21:18

In reply to Re: Serotonin Can Someone Explain the Gut Connection, posted by ed_uk2010 on October 9, 2010, at 14:31:12

That is a great explanation! Thank you!

 

Re: Serotonin Can Someone Explain the Gut Connection

Posted by Phillipa on October 12, 2010, at 14:21:18

In reply to Re: Serotonin Can Someone Explain the Gut Connection ed_uk2010, posted by Maxime on October 9, 2010, at 17:56:47

Ed yes I do agree with Maxie. Now I don't know if to give up or try to give up the low doses of them I'm on. I knew the beer was better as I felt great and no CA in my family it's heart disease and strokes. And Osteoporosis. So then Drugs that produce norepenephrine, dopamine and the other like gaba are safer and better. I was an idiot to take an ad I knew I wasn't depressed it has and always will be stress, panic, ocd thoughts, and Gad. Love PJxxx

 

Re: Serotonin Can Someone Explain the Gut Connection

Posted by Phillipa on October 12, 2010, at 14:21:19

In reply to Re: Serotonin Can Someone Explain the Gut Connection, posted by Phillipa on October 9, 2010, at 20:40:23

This is all I could find and it's experiemental. PJ

http://www.mynewsdesk.com/uk/view/news/daily-mail-proof-of-concept-for-new-bone-pill-3208

 

Re: Serotonin Can Someone Explain the Gut Connection

Posted by Phillipa on October 12, 2010, at 14:21:19

In reply to Re: Serotonin Can Someone Explain the Gut Connection, posted by Phillipa on October 9, 2010, at 23:41:31

From the NYT had no idea. Phillipa

http://www.nytimes.com/2008/11/27/health/research/27bone.html

 

Re: Serotonin Can Someone Explain the Gut Connection m

Posted by alchemy on October 12, 2010, at 14:21:19

In reply to Serotonin Can Someone Explain the Gut Connection m, posted by Phillipa on October 9, 2010, at 13:16:42

I have found that SSRIs help my gut. I'm not so bloated, food assimulates better, and I'm just don't feel as "crappy".

 

Re: Serotonin Can Someone Explain the Gut Connection Phillipa

Posted by ed_uk2010 on October 12, 2010, at 14:21:19

In reply to Re: Serotonin Can Someone Explain the Gut Connection, posted by Phillipa on October 9, 2010, at 20:40:23

>Now I don't know if to give up or try to give up the low doses of them I'm on.

That's up to you Phillipa. If you don't find SSRIs beneficial, why are you still taking fluvoxamine?

>I knew the beer was better as I felt great

I doubt that you felt great because of the beer, I think it was because your life circumstances were better. Beer can be pleasant but it's not a solution to mental health problems.

>So then Drugs that produce norepenephrine, dopamine and the other like gaba are safer and better.

Meds don't produce neurotransmitters, they modify the action of neurotransmitters. For example, SSRIs do not produce serotonin. And no, drugs that affect other neurotransmitters are not better or safer than SSRIs, they're just different. All medications have risks.

>I was an idiot to take an ad I knew I wasn't depressed it has and always will be stress, panic, ocd thoughts, and Gad.

Maybe, but some of these conditions can be treated with ADs. Just because we call them ADs doesn't mean that depression is the only condition that they can treat. Antidepressant is just a name.

Take care.

 

Re: Serotonin Can Someone Explain the Gut Connection

Posted by glydin50 on October 12, 2010, at 14:21:20

In reply to Re: Serotonin Can Someone Explain the Gut Connection, posted by Phillipa on October 9, 2010, at 20:40:23

> I was an idiot to take an ad I knew I wasn't depressed it has and always will be stress, panic, ocd thoughts, and Gad. Love PJxxx

~~~ If one has those conditions **untreated** long enough... depression is highly likely and inherently comorbid. No, beer probably isn't better and there are few folks that DON'T feel better drinking a six pack a night... for a while. There is probably MORE overall danger and risk w/ chronic ETOH consumption than w/ any number of other drugs out there.

Everything has its risks versus benefits profile. Nothing comes w/out some risk and few w/out benefit. Life is not an "all or nothing" process - absolute thinking can be a huge stumbling block. One cannot keep believing "things" are either all good or all horrible and waiting on the "all good" prefection that will NEVER arrive.... well, one CAN but that just means one is stuck not ever moving forward, not living and just waiting to die. It **does not** have to be that way... no matter the circumstances.... it's a personal choice to help oneself...

 

Re: Serotonin Can Someone Explain the Gut Connection

Posted by Phillipa on October 12, 2010, at 14:21:20

In reply to Re: Serotonin Can Someone Explain the Gut Connection, posted by glydin50 on October 11, 2010, at 15:29:19

Having visited for three weeks at a time Europe various countries one thing that struck me is that even young children consume wines and beers with meals. At age ll my Daughter in Belgium has about ll glasses of different wines in a prestigious restarant as different wines for each course. At times beer or wine was the ticket for me. 15 years ago all alchohol gone and so was my quality of life. I'd rather have quality than quantity and no Rx needed. Phillipa

 

Re: Serotonin Can Someone Explain the Gut Connection

Posted by Glydin50 on October 12, 2010, at 14:21:20

In reply to Re: Serotonin Can Someone Explain the Gut Connection, posted by Phillipa on October 11, 2010, at 21:21:06

The choice is in our power to do something different or not. To be someyhing different or not. Most people gravitate to what, on some level, works for them.

My choice was to try and put wings to my life or wallow.

 

Re: Serotonin Can Someone Explain the Gut Connection Glydin50

Posted by Phillipa on October 12, 2010, at 14:21:21

In reply to Re: Serotonin Can Someone Explain the Gut Connection, posted by Glydin50 on October 11, 2010, at 21:28:19

Then it would be back to alchohol as felt great. I did something different 15 years ago took first ad what a mistake. Phillipa ps absolutely no regrets for the benzos as allowed me a two careers when I needed them. When I didn't no drinking or meds normal as can be and happy.

 

Re: Serotonin Can Someone Explain the Gut Connection Phillipa

Posted by Glydin50 on October 12, 2010, at 14:21:21

In reply to Re: Serotonin Can Someone Explain the Gut Connection Glydin50, posted by Phillipa on October 11, 2010, at 21:55:14

We all have our choices to make.

 

Re: Serotonin Can Someone Explain the Gut Connection

Posted by glydin50 on October 12, 2010, at 14:21:21

In reply to Re: Serotonin Can Someone Explain the Gut Connection, posted by Phillipa on October 11, 2010, at 21:21:06

I'm not the only one on this thread who mentioned alcohol as potentially not being a good treatment for mental illness... I feel a bit singled out....

 

On 5th Thought

Posted by Glydin50 on October 12, 2010, at 14:21:21

In reply to Re: Serotonin Can Someone Explain the Gut Connection Phillipa, posted by Glydin50 on October 11, 2010, at 22:02:24

Disregard all my posts on this thread.

Thanks in advance.

 

Re: Serotonin Can Someone Explain the Gut Connection Phillipa

Posted by ed_uk2010 on October 12, 2010, at 14:21:22

In reply to Re: Serotonin Can Someone Explain the Gut Connection, posted by Phillipa on October 11, 2010, at 21:21:06

>Having visited for three weeks at a time Europe various countries one thing that struck me is that even young children consume wines and beers with meals.

They do have small quantities, but it's for pleasure, it's not a treatment for anything.

 

Re: Serotonin Can Someone Explain the Gut Connection ed_uk2010

Posted by Phillipa on October 12, 2010, at 20:28:24

In reply to Re: Serotonin Can Someone Explain the Gut Connection Phillipa, posted by ed_uk2010 on October 12, 2010, at 14:21:22

I feel in some way it relieves stress relaxes and prevents in some cases not all development of anxiety/depression. I didn't use it as a med just to wind down after work. And then to bed. Phillipa


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