Psycho-Babble Medication Thread 1096939

Shown: posts 1 to 8 of 8. This is the beginning of the thread.

 

Trintellix (vortioxetine) - Anyone tried it?

Posted by SLS on February 11, 2018, at 8:18:06

Hi.

I would like to know if anyone has tried Trintellix (vortioxetine), and what the results were.

I am trying to decide between Trintellex and Effexor.

Thank you.


- Scott

 

Re: Trintellix (vortioxetine) - Anyone tried it?

Posted by linkadge on February 11, 2018, at 13:27:58

In reply to Trintellix (vortioxetine) - Anyone tried it?, posted by SLS on February 11, 2018, at 8:18:06

I'd like to try Trintellix too. I don't know if it is available in Canada - but it certainly isn't off patent yet - and I don't have insurance.

On paper it looks good. I had a positive benefit to buspirone, but the metabolite and half-life issues were a problem.

Linkadge

 

Trintellix (vortioxetine) - Any comments?

Posted by SLS on February 17, 2018, at 15:07:56

In reply to Trintellix (vortioxetine) - Anyone tried it?, posted by SLS on February 11, 2018, at 8:18:06

> Hi.
>
> I would like to know if anyone has tried Trintellix (vortioxetine), and what the results were.
>
> I am trying to decide between Trintellex and Effexor.
>
> Thank you.
>
>
> - Scott


Not a single person?

Oh, well.

Any comments?


- Scott

 

Re: Trintellix (vortioxetine) - Any comments?

Posted by Viking on February 18, 2018, at 1:23:02

In reply to Trintellix (vortioxetine) - Any comments?, posted by SLS on February 17, 2018, at 15:07:56

I have tried Trintellix a couple of years ago. I had to stop it after one month due to unbearable nausea. I did not notice any other effects.

It should be said that I never have had much success with serotonergic drugs.

I hope this can help you.

 

Re: Trintellix (vortioxetine) - Any comments? Viking

Posted by SLS on February 18, 2018, at 6:54:42

In reply to Re: Trintellix (vortioxetine) - Any comments?, posted by Viking on February 18, 2018, at 1:23:02

Hi, Viking.

> I have tried Trintellix a couple of years ago. I had to stop it after one month due to unbearable nausea. I did not notice any other effects.
>
> It should be said that I never have had much success with serotonergic drugs.
>
> I hope this can help you.

It does help. Thank you.

I have bipolar depression.

I really don't have much confidence in Trintellix, but my doctor is leaning in the direction of using it before going to Effexor, which I had partial success with. I guess it makes sense to try something that I haven't taken yet. My doctor is smart, and likes to think outside the box in my case. For instance, he had me try prazosin, even though I don't qualify as having PTSD. I was dubious and was sure that it wouldn't work. I decided to let him take a shot without my putting up any resistance, despite my having doubts. It has helped me much more than most standard antidepressants. The only side effect - and it's a big one - is that I have very little sex drive. I wouldn't be without prazosin. I tried to discontinue it twice and I deteriorated quickly. It turns out that my doctor chose prazosin because of my description of chronic childhood trauma. He called it developmental PTSD. Now, it is described as C-PTSD or complex trauma disorder. I believe this contributed to the evolution of depression in my case.

https://en.wikipedia.org/wiki/Complex_post-traumatic_stress_disorder


- Scott

 

Re: Trintellix (vortioxetine) - Any comments?

Posted by Lamdage22 on March 7, 2018, at 7:25:07

In reply to Re: Trintellix (vortioxetine) - Any comments? Viking, posted by SLS on February 18, 2018, at 6:54:42

i would love to have a doctor that thinks outside the box. Because within the box, there is moslty only weightgain and anorgasmia. Thats a nischt-nischt!

 

Re: Trintellix (vortioxetine) - Any comments? SLS

Posted by beckett2 on March 8, 2018, at 23:11:35

In reply to Re: Trintellix (vortioxetine) - Any comments? Viking, posted by SLS on February 18, 2018, at 6:54:42


>
> It does help. Thank you.
>
> I have bipolar depression.
>
> I really don't have much confidence in Trintellix, but my doctor is leaning in the direction of using it before going to Effexor, which I had partial success with. I guess it makes sense to try something that I haven't taken yet. My doctor is smart, and likes to think outside the box in my case. For instance, he had me try prazosin, even though I don't qualify as having PTSD. I was dubious and was sure that it wouldn't work. I decided to let him take a shot without my putting up any resistance, despite my having doubts. It has helped me much more than most standard antidepressants. The only side effect - and it's a big one - is that I have very little sex drive. I wouldn't be without prazosin. I tried to discontinue it twice and I deteriorated quickly. It turns out that my doctor chose prazosin because of my description of chronic childhood trauma. He called it developmental PTSD. Now, it is described as C-PTSD or complex trauma disorder. I believe this contributed to the evolution of depression in my case.
>
> https://en.wikipedia.org/wiki/Complex_post-traumatic_stress_disorder
>
>
> - Scott
>
>

I've had decent success w/Trintellix. Maybe going on two years. The change from Lexapro was enlivening, but it doesn't have a fantastic effect on anxiety (esp compared to Lexapro). It may not be enough for you. Best to you.

 

Re: Trintellix (vortioxetine) - Any comments? beckett2

Posted by SLS on March 9, 2018, at 10:44:35

In reply to Re: Trintellix (vortioxetine) - Any comments? SLS, posted by beckett2 on March 8, 2018, at 23:11:35

Hi, Beckett!

> I've had decent success w/Trintellix. Maybe going on two years. The change from Lexapro was enlivening, but it doesn't have a fantastic effect on anxiety (esp compared to Lexapro). It may not be enough for you. Best to you.

Thanks for your reply. I really don't know what to expect from Trintellix. I'm actually somewhat concerned that the partial agonism of 5-HT1a receptors by Abilify will interfere with the 5-HT1a full agonism of Trintellix. Well, even if Trintellix doesn't produce an acceptable therapeutic response, I will not have lost all hope. I can try Effexor, a drug that I had some success with. If I must return to a MAOI, I would try Nardil again. I think I'll stay with 75 mg/day this time instead of pushing things higher.

I appreciate your concern.


- Scott


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