Psycho-Babble Medication Thread 1096899

Shown: posts 1 to 12 of 12. This is the beginning of the thread.

 

Lumateperone

Posted by Lamdage22 on February 7, 2018, at 13:20:43

https://en.wikipedia.org/wiki/Lumateperone

It sounds pretty freakin awesome. What do you guys think?

 

Re: Lumateperone Lamdage22

Posted by SLS on February 7, 2018, at 14:11:50

In reply to Lumateperone, posted by Lamdage22 on February 7, 2018, at 13:20:43

> https://en.wikipedia.org/wiki/Lumateperone
>
> It sounds pretty freakin awesome. What do you guys think?

Lumateperone is a very interesting drug. Thanks for posting the article.

What I noticed in the article:

The drug is a partial agonist of D2 autoreceptors (like Abilify), but a full antagonist at postsynaptic D2 receptors (unlike Abilify). It will be interesting to see if lumateperone is as effective for depression as is Abilify. If not, it would still be valuable to treat psychotic disorders because it appears to be less apt to produce movement EPS and akathisia side effects. It is also touted as producing no metabolic changes or weight gain.

I may give this thing a try if it proves effective for major depressive disorder or bipolar depression. My main motivation for switching from Abilify to something else is that Abilify produces major weight gain. Also, my triglycerides on Abilify is about 450 milligrams per deciliter. The normal value is 150 or less.


- Scott

 

Re: Lumateperone - SLS

Posted by Jeroen on February 8, 2018, at 6:13:17

In reply to Re: Lumateperone Lamdage22, posted by SLS on February 7, 2018, at 14:11:50

ITI-007

Abilify and Seroquel are causing high tryglycerines in me too i need from today, i am trying not to eat fatty foods

 

Re: Lumateperone - SLS

Posted by Lamdage22 on February 8, 2018, at 6:45:49

In reply to Re: Lumateperone - SLS, posted by Jeroen on February 8, 2018, at 6:13:17

For the meantime i would recommend Metformin for that with regular kidney checks.

 

Re: Lumateperone

Posted by Lamdage22 on February 8, 2018, at 6:55:14

In reply to Re: Lumateperone Lamdage22, posted by SLS on February 7, 2018, at 14:11:50

Those are the three things i am looking forward to. Naltrexone, Lumateperone and Rapastinel. Also i just found out the professional rehab facility is MOVING from the 3rd floor to the first. That means i can visit it without the fear of heights that i have from 2nd floor up.

All good news! How about that?

 

Re: Lumateperone Lamdage22

Posted by SLS on February 8, 2018, at 7:51:30

In reply to Re: Lumateperone, posted by Lamdage22 on February 8, 2018, at 6:55:14

> Those are the three things i am looking forward to. Naltrexone, Lumateperone and Rapastinel.

LDN? That's an interesting combination of medication. What is your rationale for choosing them?

> Also i just found out the professional rehab facility is MOVING from the 3rd floor to the first. That means i can visit it without the fear of heights that i have from 2nd floor up.
>
> All good news! How about that?

You can use some good news for a change.


- Scott

 

Re: Lumateperone

Posted by Lamdage22 on February 8, 2018, at 8:12:11

In reply to Re: Lumateperone Lamdage22, posted by SLS on February 8, 2018, at 7:51:30

> > Those are the three things i am looking forward to. Naltrexone, Lumateperone and Rapastinel.
>
> LDN? That's an interesting combination of medication. What is your rationale for choosing them?

Well Naltrexone and Rapastinel because they lack sexual side effects. Lumateperone because it lacks metabolic side effects. I have that appointment with the LDN experienced Doc on 19th February.
Naltrexone may actually enhance sex at low doses.

> > Also i just found out the professional rehab facility is MOVING from the 3rd floor to the first. That means i can visit it without the fear of heights that i have from 2nd floor up.
> >
> > All good news! How about that?
>
> You can use some good news for a change.

Thanks, Scott:)

> - Scott

 

Re: Lumateperone - SLS

Posted by PeterMartin on February 8, 2018, at 19:37:20

In reply to Re: Lumateperone - SLS, posted by Lamdage22 on February 8, 2018, at 6:45:49

> For the meantime i would recommend Metformin for that with regular kidney checks.

Thanks for the post on this med. I will definitely start following its progress.

I love how you always advocate for metformin. I started taking it last month when I began Nardil. I'm only on 1000mg now (plan to get to 1500/2000) but your comments have me optimistic that it'll offset the weight gain commonly associated with Nardil.

I really hope so. Other people having success with meds always makes me feel more optimistic.

 

Re: Lumateperone. TD andTdem risk?

Posted by Lamdage22 on February 9, 2018, at 6:13:04

In reply to Re: Lumateperone, posted by Lamdage22 on February 8, 2018, at 8:12:11

How high would be the tardive dyskinesia and tardive dementia risk with Lumateperone?

 

Re: Lumateperone. TD andTdem risk?

Posted by Christ_empowered on February 10, 2018, at 2:34:36

In reply to Re: Lumateperone. TD andTdem risk?, posted by Lamdage22 on February 9, 2018, at 6:13:04

hi lamdage

its hard to predict td rates. animal studies are one thing...pump one monkey full of haldol, another full of the new drug, see what happens...what people...whole different ball game.

 

Re: Lumateperone. TD andTdem risk?

Posted by Lamdage22 on February 10, 2018, at 16:00:50

In reply to Re: Lumateperone. TD andTdem risk?, posted by Christ_empowered on February 10, 2018, at 2:34:36

i see. They said no EPS which sounds good. I wonder if it can be megadosed. But we shouldnt rely on meds that are not out yet. We dont know what what will happen. Life with mental problems is a marathon.

 

What does Lumateperone do to dopamine receptors?

Posted by Lamdage22 on February 16, 2018, at 3:26:06

In reply to Re: Lumateperone. TD andTdem risk?, posted by Christ_empowered on February 10, 2018, at 2:34:36

Hey yall,

Can anyone explain what Lumateperone does to dopamine receptors, especially at high dosages?

thx
Lamdage


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