Psycho-Babble Medication Thread 1095498

Shown: posts 1 to 22 of 22. This is the beginning of the thread.

 

Which benzo with short half life?

Posted by Lamdage22 on October 19, 2017, at 13:36:55

Hey guys,

Lorazepams effects last way too long for me if i take two or three prior to a date. I want to take sth where i am anxiety free for two hours. Not more.

thx

 

Re: Which benzo with short half life?

Posted by joe f on October 19, 2017, at 19:00:28

In reply to Which benzo with short half life?, posted by Lamdage22 on October 19, 2017, at 13:36:55

zanax shorter half life ---klonopin longer half life

 

Re: Which benzo with short half life?

Posted by baseball55 on October 19, 2017, at 19:34:33

In reply to Which benzo with short half life?, posted by Lamdage22 on October 19, 2017, at 13:36:55

> Hey guys,
>
> Lorazepams effects last way too long for me if i take two or three prior to a date. I want to take sth where i am anxiety free for two hours. Not more.
>
> thx
> Two or three at what dosage? That's a lot of benzo, even at 0.5mg lorazapem.

 

Re: Which benzo with short half life?

Posted by Lamdage22 on October 20, 2017, at 0:44:36

In reply to Re: Which benzo with short half life?, posted by baseball55 on October 19, 2017, at 19:34:33

i am thinking midazolam. Two or three at 1mg.

 

Re: Which benzo with short half life?

Posted by Lamdage22 on October 20, 2017, at 11:34:48

In reply to Re: Which benzo with short half life?, posted by Lamdage22 on October 20, 2017, at 0:44:36

This is my "going on a date" dosage.

 

Re: Which benzo with short half life?

Posted by rjlockhart37 on October 20, 2017, at 12:31:22

In reply to Which benzo with short half life?, posted by Lamdage22 on October 19, 2017, at 13:36:55

the shortest half-life through prescribing is Halcion, triazolam, it was used for sleep in the late 1980s in the US, its half-life is only 1 hour, they advertised it as getting you to sleep fast, and waking up rested and awake it's potent, it sedates heavily, but what i read is that the next day you have anxiety..when it wears off i read people would go into anger and anxiety states if you research on past use of triazolam you'll read many cases of bad reports, but others it works like a dream.

 

Re: Which benzo with short half life?

Posted by Lamdage22 on October 22, 2017, at 4:59:37

In reply to Re: Which benzo with short half life?, posted by rjlockhart37 on October 20, 2017, at 12:31:22

Will midazolam or triazolam give me similar social anxiety relief like Lorazepam?

When high on Lorazepam, nobody would think that i am on it because I behave normally. Is it the same with midazolam or triazolam?

THX
Lamdage

 

Re: Which benzo with short half life?

Posted by phidippus on October 22, 2017, at 13:21:49

In reply to Re: Which benzo with short half life?, posted by Lamdage22 on October 22, 2017, at 4:59:37

Midazolam is for intravenous use. Intravenous midazolam is indicated for procedural sedation

Eric

 

Re: Which benzo with short half life?

Posted by SLS on October 22, 2017, at 16:43:51

In reply to Which benzo with short half life?, posted by Lamdage22 on October 19, 2017, at 13:36:55

Triazolam (Halcion) is a very potent hypnotic benzodiazepine with a very short half life. I don't know what else this drug is used for other than promoting sleep.


- Scott

 

Re: Which benzo with short half life?

Posted by Lamdage22 on October 23, 2017, at 10:20:32

In reply to Re: Which benzo with short half life?, posted by SLS on October 22, 2017, at 16:43:51

I need a social anxiety fix for a couple of hours. But i want to be sober again the next day.

 

Re: Which benzo with short half life? Lamdage22

Posted by SLS on October 23, 2017, at 15:35:24

In reply to Re: Which benzo with short half life?, posted by Lamdage22 on October 23, 2017, at 10:20:32

> I need a social anxiety fix for a couple of hours. But i want to be sober again the next day.

Has anyone already suggested Xanax (alprazolam) non-XR? Xanax has a fairly short half-life for a benzodiazepine. The average time is 11.2 hours, although this is variable interindividually. Compared to Ativan (lorazepam), Xanax usually penetrates anxiety more completely, and may have a mild antidepressant effect. Xanax can produce a greater feeling of relaxation than Ativan. One needs to beware of behavioral disinhibition with Xanax, though.


- Scott

 

Re: Which benzo with short half life?

Posted by Lamdage22 on October 25, 2017, at 10:37:52

In reply to Re: Which benzo with short half life? Lamdage22, posted by SLS on October 23, 2017, at 15:35:24

Hi Scott,

thanks for your post. no one has. I have experience with Alprazolam. Half life is shorter than Lorazepam?

> Has anyone already suggested Xanax (alprazolam) non-XR? Xanax has a fairly short half-life for a benzodiazepine. The average time is 11.2 hours, although this is variable interindividually. Compared to Ativan (lorazepam), Xanax usually penetrates anxiety more completely, and may have a mild antidepressant effect. Xanax can produce a greater feeling of relaxation than Ativan. One needs to beware of behavioral disinhibition with Xanax, though.
>
>
> - Scott

 

Re: Which benzo with short half life? Lamdage22

Posted by SLS on October 25, 2017, at 16:21:50

In reply to Re: Which benzo with short half life?, posted by Lamdage22 on October 25, 2017, at 10:37:52

> Hi Scott,
>
> thanks for your post. no one has. I have experience with Alprazolam. Half life is shorter than Lorazepam?


> > Has anyone already suggested Xanax (alprazolam) non-XR? Xanax has a fairly short half-life for a benzodiazepine. The average time is 11.2 hours, although this is variable interindividually. Compared to Ativan (lorazepam), Xanax usually penetrates anxiety more completely, and may have a mild antidepressant effect. Xanax can produce a greater feeling of relaxation than Ativan. One needs to beware of behavioral disinhibition with Xanax, though.

I see that lorazepam has a 12 hour half-life, which is nearly identical to alprazolaam. However, the experience of hangover may be different between the two drugs. If the binding affinity of alprazolam is higher than that of lorazepam, you might be able to use a dosage of alprazolam that is low enough to prevent an extended hangover. That's just a guess, though.


- Scott

 

Re: Which benzo with short half life?

Posted by Lamdage22 on October 26, 2017, at 2:30:50

In reply to Re: Which benzo with short half life? Lamdage22, posted by SLS on October 25, 2017, at 16:21:50

Hi Scott,

i dont get a hangover from Lorazepam. Plus nobody notices that i am on the drug. Maybe i will just stick with Lorazepam then.

 

Re: Which benzo with short half life?

Posted by SLS on October 26, 2017, at 2:37:12

In reply to Re: Which benzo with short half life?, posted by Lamdage22 on October 26, 2017, at 2:30:50

> Hi Scott,
>
> i dont get a hangover from Lorazepam. Plus nobody notices that i am on the drug. Maybe i will just stick with Lorazepam then.

I didn't mean to say that alprazolam was more likely to produce a hangover effect than is lorazepam.

Let me ask this question: What would you like an anxiolytic drug to do that lorazepam doesn't do? What's missing with lorazepam?


- Scott

 

Re: Which benzo with short half life?

Posted by Lamdage22 on October 26, 2017, at 2:55:08

In reply to Re: Which benzo with short half life?, posted by SLS on October 26, 2017, at 2:37:12

Hi Scott,

lorazepams effects last too long

 

Re: Which benzo with short half life?

Posted by Lamdage22 on October 26, 2017, at 4:17:22

In reply to Re: Which benzo with short half life?, posted by Lamdage22 on October 26, 2017, at 2:55:08

especially at high dosages.

 

Re: Which benzo with short half life?

Posted by SLS on October 26, 2017, at 8:05:48

In reply to Re: Which benzo with short half life?, posted by Lamdage22 on October 26, 2017, at 2:55:08

> Hi Scott,
>
> lorazepams effects last too long

There is a Xanax XR extended-release preparation. I should think that enough people were unhappy with the short length of time that alprazolam acts for such that there is a market for the extended-release version. Sometimes, half-life is not a reliable measure of how long a drug's effects last for. Regular alprazolam will work for about 5 hours. Lorazepam is closer to 8 hours.

What are you using lorazepam for?

Perhaps alprazolam is worth a try, anyway. You won't know how well it matches your requirements until you try it.

Good luck.


- Scott

 

Re: Which benzo with short half life?

Posted by Lamdage22 on October 26, 2017, at 9:46:17

In reply to Re: Which benzo with short half life?, posted by SLS on October 26, 2017, at 8:05:48

I use it when i am triggered by a severe stressor or for dates where i normally would be extremely nervous.

Alprazolam sounds good.

Maybe i can get it tomorrow.

 

Re: Which benzo with short half life?

Posted by Lamdage22 on October 26, 2017, at 14:15:30

In reply to Re: Which benzo with short half life?, posted by Lamdage22 on October 26, 2017, at 9:46:17

i wonder if alprazolam will behave like lorazepam in the way that my company does not notice that i am on it.

 

Re: Which benzo with short half life?

Posted by Melusine on October 28, 2017, at 14:01:17

In reply to Re: Which benzo with short half life?, posted by Lamdage22 on October 26, 2017, at 9:46:17

Depends what you need it for, and how you're planning on taking the drug. The route of administration also affects the duration of action. Some benzos can be delivered by routes other than orally.

Also, there are multiple different types of half-lives, and none of which is the sole determinant of duration of action. Elimination half-life (which is usually what is meant by "half-life" if type is not specified) is itself quite variable. It can be affected by other drugs you're taking, if you've eaten recently, genetic variations in metabolism...you can see why it's so variable.

Oh, and it also matters what country you're in. Certain benzos aren't available in some countries. For example, I'm not sure whether you can get oral midazolam in the States. I've only ever heard of it being used in the USA either as part of a general anaesthesia cocktail, or for sedating patients who need to be mechanically ventilated.

I'd probably suggest either alprazolam, or taking lorazepam somewhat earlier than you ordinarily would, so that it wears off by the time you need it to. What dose of lorazepam do you take?

-Melusine

 

Re: Which benzo with short half life?

Posted by Lamdage22 on November 1, 2017, at 7:51:59

In reply to Re: Which benzo with short half life?, posted by Melusine on October 28, 2017, at 14:01:17

alprazolam sounds good. thanks


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