Psycho-Babble Medication Thread 1093358

Shown: posts 1 to 10 of 10. This is the beginning of the thread.

 

Lyrica, Gabapentin, Phenebut neurogenesis

Posted by linkadge on December 2, 2016, at 18:11:18

Apparently 'gabapentanoids' (i.e. pregabalin, gabapentin and possibly phenebut) enhance hippocampal neurogenesis.

https://www.ncbi.nlm.nih.gov/pubmed/22572885

Linkadge

 

Re: Lyrica, Gabapentin, Phenebut neurogenesis

Posted by SLS on December 3, 2016, at 8:09:43

In reply to Lyrica, Gabapentin, Phenebut neurogenesis, posted by linkadge on December 2, 2016, at 18:11:18

> Apparently 'gabapentanoids' (i.e. pregabalin, gabapentin and possibly phenebut) enhance hippocampal neurogenesis.
>
> https://www.ncbi.nlm.nih.gov/pubmed/22572885
>
> Linkadge

I can't take pregabalin or gabapentin. They produce cognitive blunting and some dissociation that persists long after the drug is discontinued.

What other drugs or substances enhance hippocampal neurogenesis?


- Scott

 

Re: Lyrica, Gabapentin, Phenebut neurogenesis

Posted by linkadge on December 3, 2016, at 14:28:57

In reply to Re: Lyrica, Gabapentin, Phenebut neurogenesis, posted by SLS on December 3, 2016, at 8:09:43

Hmm...

There are a long list of them...

I would go to pubmed.com and search for

"enhances neurogenesis"

Everything from hormones, to monoamine agonists.

Linkadge

 

Re: Lyrica, Gabapentin, Phenebut neurogenesis

Posted by Prefect on December 6, 2016, at 19:56:41

In reply to Re: Lyrica, Gabapentin, Phenebut neurogenesis, posted by linkadge on December 3, 2016, at 14:28:57

and regular aerobic execrcise

 

Re: Lyrica, Gabapentin, Phenebut neurogenesis

Posted by chumbawumba on January 12, 2017, at 4:14:51

In reply to Lyrica, Gabapentin, Phenebut neurogenesis, posted by linkadge on December 2, 2016, at 18:11:18

> Apparently 'gabapentanoids' (i.e. pregabalin, gabapentin and possibly phenebut) enhance hippocampal neurogenesis.
>
> https://www.ncbi.nlm.nih.gov/pubmed/22572885
>
> Linkadge

I don't know if this link has been posted before but it's saying that R-Phenibut is a gabapentinoid.

https://www.ncbi.nlm.nih.gov/pubmed/26234470

Sounds like it could be pretty helpful. Never tried it myself.

Although if you have addictive tendencies self medicating with Phenibut seems dicey. I just was in a thread over on bluelight with a guy who was abusing it and got up to 32 grams a day! Apparently your tolerance builds very quickly because this escalated over the course of a couple months. And then he quit cold turkey! Just when you think you've heard it all.

So now he's got severe anhedonia and is in a real bind.

 

Re: Lyrica, Gabapentin, Phenebut neurogenesis chumbawumba

Posted by SLS on January 12, 2017, at 7:08:49

In reply to Re: Lyrica, Gabapentin, Phenebut neurogenesis, posted by chumbawumba on January 12, 2017, at 4:14:51

Hi.

> Although if you have addictive tendencies self medicating with Phenibut seems dicey. I just was in a thread over on bluelight with a guy who was abusing it and got up to 32 grams a day! Apparently your tolerance builds very quickly because this escalated over the course of a couple months. And then he quit cold turkey! Just when you think you've heard it all.
>
> So now he's got severe anhedonia and is in a real bind.

Off the top of my head: If your friend believes that he has no alternatives, perhaps he can explore:

Lamictal
Abilify
Nardil
Effexor
Memantine (Namenda)

Memantine might be a long shot, but if he has OCD, it might be worth a try.

I think Linkadge would have some good ideas.

If Nardil is not to be tried, he might consider a combination of Effexor + nortriptyline + Lamictal.


- Scott

 

Re: Lyrica, Gabapentin, Phenebut neurogenesis linkadge

Posted by SLS on January 12, 2017, at 7:11:37

In reply to Re: Lyrica, Gabapentin, Phenebut neurogenesis, posted by linkadge on December 3, 2016, at 14:28:57

Hi Linkadge. I appreciate your input.

> Hmm...
>
> There are a long list of them...
>
> I would go to pubmed.com and search for
>
> "enhances neurogenesis"
>
> Everything from hormones, to monoamine agonists.
>
> Linkadge

Thanks.


- Scott

 

Re: Lyrica, Gabapentin, Phenebut neurogenesis

Posted by chumbawumba on January 12, 2017, at 17:20:59

In reply to Lyrica, Gabapentin, Phenebut neurogenesis, posted by linkadge on December 2, 2016, at 18:11:18

> Apparently 'gabapentanoids' (i.e. pregabalin, gabapentin and possibly phenebut) enhance hippocampal neurogenesis.
>
> https://www.ncbi.nlm.nih.gov/pubmed/22572885
>
> Linkadge

I'm biased because I take it myself but I think a little bit of Lithium could help almost anyone with depression who is not getting 100% symptom relief from their primary medication(s). Even just 600 mg in my experience can turn the volume way up on the AD. And I'm a tough nut so I bet a lot of people could take smaller doses and benefit. It's a somewhat underappreciated option I think.

https://www.ncbi.nlm.nih.gov/pubmed/21803056

Poor mice, what we do to them, God forgive us for what we to to our fellow beings in order to help ourselves.

 

Re: Lyrica, Gabapentin, Phenebut neurogenesis chumbawumba

Posted by SLS on January 12, 2017, at 22:10:14

In reply to Re: Lyrica, Gabapentin, Phenebut neurogenesis, posted by chumbawumba on January 12, 2017, at 17:20:59

I take only 300 mg/day of lithium, and it does help. I also take it in the hopes that it will help prevent Alzheimer's Dementia.


- Scott

 

Re: Lyrica, Gabapentin, Phenebut neurogenesis SLS

Posted by chumbawumba on January 12, 2017, at 22:46:13

In reply to Re: Lyrica, Gabapentin, Phenebut neurogenesis chumbawumba, posted by SLS on January 12, 2017, at 22:10:14

> I take only 300 mg/day of lithium, and it does help. I also take it in the hopes that it will help prevent Alzheimer's Dementia.
>
>
> - Scott

Didn't know it prevented dementia. See it's good for everything , put it in the drinking water!


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