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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 16 of 16. This is the beginning of the thread.
Posted by mogger on January 27, 2014, at 16:23:28
Zoloft has helped me with my ocd and Buspar was a great addition for anxiety (went off it because of weight gain unfortunately). I sweat so heavily with Zoloft and as I say Buspar caused weight gain. I saw my pdoc the other day and he said that Viibryd and Brintellix both have similarities to both an ssri and buspar combined. In other words he said I might be able to get the same benefit of taking either Viibryd or Brintellix as opposed to taking both Zoloft and Buspar. Has anyone had experience with this scenario? Many thanks for your thoughts,
Mogger
Posted by phidippus on January 27, 2014, at 20:45:54
In reply to Viibryd or Brintellix= SSRI + Buspar?, posted by mogger on January 27, 2014, at 16:23:28
I responded strongly to Viibryd. Buspar is 5ht1a agonist-agonizing this receptor provides both an anxiolytic and antidepressant effect. Viibryd is a partial 5ht1a agonist and Brintellix is a 5ht1a full agonist. Brintellix is also a 5-HT1B receptor partial agonist, a 5-HT1D receptor antagonist, 5-HT3A receptor antagonist, and a 5-HT7 receptor antagonist-all of which contributes to its antidepressant and anxiolytic effects.
Latuda, Geodon and Abilify are also 5ht1a agonists. In OCD, there is often too much dopamine in certain parts of the brain, so the tactic of adding an atypical antipsychotic is used. Adding an atypical with 5ht1a agonism sometimes proves particularly effective in treating OCD.
Eric
Posted by mogger on January 27, 2014, at 21:31:56
In reply to Re: Viibryd or Brintellix= SSRI + Buspar? » mogger, posted by phidippus on January 27, 2014, at 20:45:54
Eric,
Thanks for clearing up all this it is very interesting. It sounds like Brintellix could be quite powerful. Are you still on Viibryd? I remember your horrible Serotonin Syndrome experience so I am not sure if you are off it.
Joseph
Posted by Phillipa on January 27, 2014, at 22:35:38
In reply to Re: Viibryd or Brintellix= SSRI + Buspar? » phidippus, posted by mogger on January 27, 2014, at 21:31:56
Eric didn't you discontinue it? Phillipa
Posted by phidippus on January 28, 2014, at 15:23:43
In reply to Re: Viibryd or Brintellix= SSRI + Buspar?, posted by Phillipa on January 27, 2014, at 22:35:38
Viibryd pooped out on me. I'm on Lexapro now.
Eric
Posted by phidippus on January 28, 2014, at 15:30:09
In reply to Re: Viibryd or Brintellix= SSRI + Buspar? » phidippus, posted by mogger on January 27, 2014, at 21:31:56
I am not on Viibryd, unfortunately it pooped out on me. Now I'm on Lexapro.
Eric
Posted by mogger on January 28, 2014, at 16:14:16
In reply to Re: Viibryd or Brintellix= SSRI + Buspar? » mogger, posted by phidippus on January 28, 2014, at 15:30:09
Sorry to hear it. How is the lexapro? Have you seen this new medication called Fetzima yet?
Joseph
Posted by phidippus on January 28, 2014, at 16:25:03
In reply to Re: Viibryd or Brintellix= SSRI + Buspar? » phidippus, posted by mogger on January 28, 2014, at 16:14:16
Its actually the first time I've experienced tachyphylaxis with a drug. All of a sudden I started getting panic attacks and depressive symptoms. I switched to the Lexapro and the problems ceased.
Fetzima is just another SNRI, though it does seem pretty potent.
Eric
Posted by joe f on January 28, 2014, at 17:23:29
In reply to Re: Viibryd or Brintellix= SSRI + Buspar? » mogger, posted by phidippus on January 28, 2014, at 16:25:03
viibryd is a weird drug
Posted by Phillipa on January 28, 2014, at 20:08:42
In reply to Re: Viibryd or Brintellix= SSRI + Buspar?, posted by joe f on January 28, 2014, at 17:23:29
My friend tried it and think it increased somulence for him? Phillipa
Posted by porkpiehat on April 10, 2014, at 12:44:49
In reply to Re: Viibryd or Brintellix= SSRI + Buspar?, posted by Phillipa on January 28, 2014, at 20:08:42
Is anyone worried that Brintellix would be too potent? I won't take full doses of SSRI's b.c. they numb me out too much and can make me manic.
I loved the combo of Celexa + buspar until the rage started (1pp I think).
Right now I need more control of obsessive thinking and concentration, but I don't want to be super numb. Brintellix is FULL 5hta1 agonist? Would that be a sledgehammer cure for a hangnail?
Posted by phidippus on April 11, 2014, at 16:47:21
In reply to Re: Viibryd or Brintellix= SSRI + Buspar?, posted by porkpiehat on April 10, 2014, at 12:44:49
Brintellix proved super effective for my OCD. OCD will never be a hangnail and Brintellix is just strong enough for it.
Eric
Posted by porkpiehat on April 11, 2014, at 17:16:23
In reply to Re: Viibryd or Brintellix= SSRI + Buspar?, posted by porkpiehat on April 10, 2014, at 12:44:49
hehe I just got my samples today!
I'm down to 10 mgs of Celexa for the switch and I feel great. I almost don't want to ramp back up on anything. My mind is a little less busy and my sex drive is back, and I'm getting a good range of emotion, but I'm sure it will turn dark if I wait too long.
Hopefully I'll have some positive reports myself!
Posted by mogger on April 11, 2014, at 17:56:27
In reply to Re: Viibryd or Brintellix= SSRI + Buspar? » porkpiehat, posted by phidippus on April 11, 2014, at 16:47:21
Do you think if you had gone up to 20mg slower you could have continued on it or was the throwing up inevitable?
Posted by phidippus on April 11, 2014, at 19:12:48
In reply to Re: Viibryd or Brintellix= SSRI + Buspar? » phidippus, posted by mogger on April 11, 2014, at 17:56:27
I think I started upchucking at the 10 mg level. I couldn't have gone up more slowly.
Eric
Posted by porkpiehat on April 14, 2014, at 15:39:20
In reply to Re: Viibryd or Brintellix= SSRI + Buspar? » mogger, posted by phidippus on April 11, 2014, at 19:12:48
Day two here. Nothing negative to report! Only 5mgs however and 5mgs celexa
This is the end of the thread.
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