Psycho-Babble Medication Thread 1015824

Shown: posts 1 to 25 of 35. This is the beginning of the thread.

 

found out exactly what dose of ketamine i'm on

Posted by poser938 on April 17, 2012, at 17:43:40

i called the pharmacy and they said each spray has 0.1mgs of ketamine. 3 sprays in each nostril isnt even a milligram in all.

 

Re: found out exactly what dose of ketamine i'm on » poser938

Posted by Phillipa on April 17, 2012, at 18:43:52

In reply to found out exactly what dose of ketamine i'm on, posted by poser938 on April 17, 2012, at 17:43:40

So what now?

 

Re: found out exactly what dose of ketamine i'm on

Posted by poser938 on April 17, 2012, at 18:50:54

In reply to Re: found out exactly what dose of ketamine i'm on » poser938, posted by Phillipa on April 17, 2012, at 18:43:52

i'm really not sure. but, im going back to my regular medical doc. i talked to him like 2 months ago about ketamine and he said he wouldnt feel comfortable giving me an injection, especially without reading for hours about the effects of ketamine and how to give the injections. so, i'm printing off all the official studies that he might need. and i'm going to tell him he's going to have to do something. and just make him feel comfortable giving me ketamine, and let him know i have zero interest in a lawsuit if something goes bad.

 

Re: found out exactly what dose of ketamine i'm on » poser938

Posted by Phillipa on April 17, 2012, at 20:58:18

In reply to Re: found out exactly what dose of ketamine i'm on, posted by poser938 on April 17, 2012, at 18:50:54

Maybe if you could supply your doc with the name of docs that are using Ketamine IV and he could speak with them that might help? Phillipa

 

Re: found out exactly what dose of ketamine i'm on » poser938

Posted by sigismund on April 17, 2012, at 21:09:37

In reply to found out exactly what dose of ketamine i'm on, posted by poser938 on April 17, 2012, at 17:43:40

That makes more sense of your experience.

 

Re: found out exactly what dose of ketamine i'm on » poser938

Posted by europerep on April 18, 2012, at 10:04:14

In reply to found out exactly what dose of ketamine i'm on, posted by poser938 on April 17, 2012, at 17:43:40

> i called the pharmacy and they said each spray has 0.1mgs of ketamine. 3 sprays in each nostril isnt even a milligram in all.

Didn't you say earlier that your ketamine HCl Solution was 50mg per ml? In order for one pump to contain 0.1mg, it would have to be a pump of 1/500 of a ml, or 0.002ml. I think this is highly unlikely.

I find this whole story extremely strange. You are getting a treatment that isn't even supposed to be delivered in a non-clinical study setting, and your doctor doesn't even provide you with the precise amount of ketamine you are supposed to take? With all due respect, that doctor is a quack!

If you intend to keep taking the ketamine, which I fully understand, go see that doctor and ask him to explain you IN DETAIL how the treatment is going to go down.

 

Re: found out exactly what dose of ketamine i'm on

Posted by Sailboat77 on April 18, 2012, at 10:27:58

In reply to Re: found out exactly what dose of ketamine i'm on » poser938, posted by europerep on April 18, 2012, at 10:04:14

My depression has been extremely treatment resistant and I'm very much in need of a new course of treatment. My psychiatrist had mentioned Ketamine as a possibility but we didn't talk much about it.

I have a few questions: Is Ketamine FDA approved for the treatment of depression? Do you have to be in a medical trial to get Ketamine treatment? What's the most effective way of administering Ketamine and how often do you need treatments?

 

Re: found out exactly what dose of ketamine i'm on » Sailboat77

Posted by europerep on April 18, 2012, at 16:46:36

In reply to Re: found out exactly what dose of ketamine i'm on, posted by Sailboat77 on April 18, 2012, at 10:27:58

> I have a few questions: Is Ketamine FDA approved for the treatment of depression?

No. And, as far as I know, ketamine isn't approved for long-term use at all. It is used as an anaesthetic in hospitals, and for a very small number of patients for pain therapy. This latter use is of course long-term, but I'm not sure whether ketamine is actually approved for that use.

> Do you have to be in a medical trial to get Ketamine treatment?

Technically, yes. As this thread shows, that is not always what happens in reality. Other members here know more about docs in the US that prescribe ketamine for depression.

> What's the most effective way of administering Ketamine and how often do you need treatments?

Answers to these questions are not yet established. Studies usually go with IV infusions that administer the dose over a period of forty minutes. There is also a study going on (or maybe already finished) with intranasal administration. In the studies that have been finished so far, antidepressive effects typically faded out after a week or two, sometimes longer though. Long-term treatment of refractory depression with ketamine has not been researched, i.e. there is zero scientific data on how this would work in terms of dosage, routes of administration, side effects, and so on.

I hope this helps!

ER

 

Re: found out exactly what dose of ketamine i'm on » poser938

Posted by phidippus on April 18, 2012, at 22:24:06

In reply to found out exactly what dose of ketamine i'm on, posted by poser938 on April 17, 2012, at 17:43:40

You'd probably have to down the whole bottle to feel any effect.

Eric

 

Re: found out exactly what dose of ketamine i'm on » phidippus

Posted by europerep on April 19, 2012, at 16:30:43

In reply to Re: found out exactly what dose of ketamine i'm on » poser938, posted by phidippus on April 18, 2012, at 22:24:06

> You'd probably have to down the whole bottle to feel any effect.

This is not exactly a reasonable comment to make in this context.

P938, go see your doctor and talk this through with him, we here on the board cannot help you with this.


 

Re: found out exactly what dose of ketamine i'm on

Posted by poser938 on April 19, 2012, at 17:35:36

In reply to Re: found out exactly what dose of ketamine i'm on » poser938, posted by phidippus on April 18, 2012, at 22:24:06

well, to be honest, you said what has been on my mind. i'm strongly considering drinking the whole bottle. the doc that prescribed it is very expensive and we have already spent 500 dollars in 3 weeks for him. so, funds are running low.

i went to my regular doc yesterday and he wasnt interested in helping me with injecting a legitimate dose of ketamine. after that i felt so desperate i stopped at the emergency room at the nice big hospital they just built in my city. i figured they have just about everything there in order to help me, and the only thing holding them back is them just being willing to help me. i brought my bottle of ketamine with me to show them that my psychiatrist did indeed prescribe it for me, but only in baby doses. i told them all day thoughts of suicide are on my mind(which they are) and they said all they can do for me is send me to a mental hospital where i can have many of my rights taken away from me and be given one of these fantastic antidepressants (sarcasm) that they have out these days. otherwise, i just have to go back to my regular psychiatrist.

now, im going to look into the clinical trials and hope to God i can get into one quickly. it says on many of them they dont accept people with high blood pressure, even when controlled by medication. so this may be a problem for me. and also, they may be loke 500miles away.

so, like i said, i'm considering just drinking what i have left, which is about 250mgs i think. i'm going down hill too fast, and feeling horrible. it seems doctors would rather me jump off cliff, than give me the legitimate treatment i need.
i even tried contacting my doctor, but despite what hes being paid, he doesnt take phone calls. i had to speak to one of his very "unknowledgeable" (is that a word?) nurses that didnt even know what dose of ketamine i was on. but anyways, i was calling to see if he was willing to either give me a dose of ketamie that is used in all the studies or if he could send me to someone that is willing to. but the nurse said i would have to make an appointment for that, which i cant afford anymore.

so, any advice for me if i decide to drink it? i know it takes amuch higher dose when taken orally to get the same effects as when injected.

 

Re: found out exactly what dose of ketamine i'm on » poser938

Posted by phidippus on April 19, 2012, at 18:19:00

In reply to Re: found out exactly what dose of ketamine i'm on, posted by poser938 on April 19, 2012, at 17:35:36

What your dealing with is a chemical substance that only now is being studied as a treatment for depression. It is a good sign that clinical trials have been developed to test the drug, but at this point no one knows how the drug should be administered. I haven't seen anything indicating dosages ascribed for daily administration.

You're lucky you got someone to write a script for you-Ketamine via nasal spray is novel. I wonder if he's written such a script before. He may not even know whether the script would work.

Go ahead and down the bottle. Its not going to kill you.

Just realize getting Ketamine treatment may not be so easy adn you're only option may be a clinical trial.

Eric

 

Re: found out exactly what dose of ketamine i'm on

Posted by poser938 on April 19, 2012, at 18:36:00

In reply to Re: found out exactly what dose of ketamine i'm on » poser938, posted by phidippus on April 19, 2012, at 18:19:00

http://www.erowid.org/chemicals/ketamine/ketamine_dose.shtml

this is the site i'm going by that talks abouthow ketamine is dosed, and the efects of it.

i was considering injecting it, but the pharmacy said it is justketamine dissolved in purified water, so i dont think it can be injected.
it would have to be in a saline solution

 

Re: found out exactly what dose of ketamine i'm on » poser938

Posted by Phillipa on April 19, 2012, at 18:57:58

In reply to Re: found out exactly what dose of ketamine i'm on, posted by poser938 on April 19, 2012, at 18:36:00

Poser please do not do this. Please? Phillipa

 

Re: found out exactly what dose of ketamine i'm on

Posted by poser938 on April 19, 2012, at 19:19:15

In reply to Re: found out exactly what dose of ketamine i'm on » poser938, posted by Phillipa on April 19, 2012, at 18:57:58

i'm going to try and hold out a bit longer. maybe another week. and i'm going to try and get help from a doctor or a clinical trial, or a university where students are training or something.

i have read too many experiences where someone talks about taking ketamine in effective doses orally, or injecting it, or nasal, and they end up feeling much better.

i am tired of these doctors making it as hard as possible for me to get the help i need, and it is making me desperate.
they are showing me just how fictional the show House really is. i love the doctor on that show.

 

Re: found out exactly what dose of ketamine i'm on » phidippus

Posted by europerep on April 20, 2012, at 7:26:49

In reply to Re: found out exactly what dose of ketamine i'm on » poser938, posted by phidippus on April 19, 2012, at 18:19:00

> Go ahead and down the bottle. Its not going to kill you.

I can't believe it. Are you freakin' nuts!? Poser knows neither the quantity of ketamine solution he has, nor its strength, so telling him to down the whole bottle is about as irresponsible as it gets. Seriously man, if this were my board I'd ban you for that comment. This is dangerous! His guess that his bottle would contain around 250mg is as precise as his guess of which dose he was on, which ranged some from 0.6mg to 300mg. And even if it were 250mg, that is actually a dose that will have a pretty strong psychoactive effect on someone with a low tolerance to ketamine. Noone knows what a suicidal person would do on that trip.

So, P938, just for the record, DO NOT DRINK the whole bottle, and CERTAINLY not without knowing beforehand the exact amount of ketamine in it.

 

Re: found out exactly what dose of ketamine i'm on » poser938

Posted by europerep on April 20, 2012, at 7:35:52

In reply to Re: found out exactly what dose of ketamine i'm on, posted by poser938 on April 19, 2012, at 17:35:36

Ok, the experience you describe here in your threads has actually only brought a certain answer to the question whether that doctor is a quack who's only after the money - the answer is obviously yes.

If you don't get a clear answer on how much ketamine you've been taking, there is no way to conclude for you what efficacy ketamine has for treating your depression. However, you will probably have difficulty getting into ketamine trials because prior ketamine use is usually an exclusion criteria, i.e. they won't accept you. Of course you don't have to tell them you took ketamine, but your "real" doctor who would have to provide information about your case to the researchers would probably mention it. So if you want to know for sure whether ketamine is effective for you or not, you have to stick with the doctor who gave it to you now. Maybe you could drop by the pharmacy and have them explain it to you in detail. That's what I would do.

 

Re: found out exactly what dose of ketamine i'm on

Posted by poser938 on April 20, 2012, at 17:10:42

In reply to Re: found out exactly what dose of ketamine i'm on » poser938, posted by europerep on April 20, 2012, at 7:35:52

i did find out my exact dose now. it is 0.1mgs in each spray. and and the amount he has me on isn't even a milligram.
and i already cant get in just about all the clinical trials because i have high blood pressure. but, there is 1 trial in connecticut that will let someone in if they have high blood pressure. they are using it in the emergency room at the hospital there, so basically i think i just have to show up sayng that im very suicidal and depressed. and my doctor havng me on baby doses might not affect their decision on whether or not to try higher doses.

one of my problems is that i cant really afford to see this doctor anymore, especially if he isnt going to try the doses that are used in all the studies and clinical trials for ketamine.

but, before i decide to drink the ketamine i have left over, i'm going to make sure i know exactly how much i have left.

 

Re: found out exactly what dose of ketamine i'm on » europerep

Posted by phidippus on April 20, 2012, at 17:45:46

In reply to Re: found out exactly what dose of ketamine i'm on » poser938, posted by europerep on April 20, 2012, at 7:35:52

Your current doctor doesn't haave to have any invovlvement in any trials you may consider. As for previous Ketamine use all you have to tell them is no.

What are you hoping will come of the trial?

Eric

 

Re: found out exactly what dose of ketamine i'm on » europerep

Posted by phidippus on April 20, 2012, at 17:53:08

In reply to Re: found out exactly what dose of ketamine i'm on » phidippus, posted by europerep on April 20, 2012, at 7:26:49

He knows the strength of the solution he's on - .1mg/ml. I doubt the total capacity of the bottle he has is 250 ml/mg and even then, that's not a scary dose of Ketamine. I'm just trying to make the point that his doctor is taking him for a ride.

Eric

 

Re: found out exactly what dose of ketamine i'm on

Posted by poser938 on April 20, 2012, at 17:59:47

In reply to Re: found out exactly what dose of ketamine i'm on » europerep, posted by phidippus on April 20, 2012, at 17:45:46

well im not even sure if i will be able to make it to connecticut. i live in the south, so thats a far distance. it just might be one of my options if i cant figure anyhting else out.

my current psychiatrist isn't interested in trying higher doses.

 

Re: found out exactly what dose of ketamine i'm on » poser938

Posted by phidippus on April 20, 2012, at 18:04:54

In reply to Re: found out exactly what dose of ketamine i'm on, posted by poser938 on April 19, 2012, at 19:19:15

I'm worried you're banking too much on Ketamine.

Find the closest clinical trial and write whoever's coordinating the trial. That's how I get into most trials I ever go for.

Eric

 

Re: found out exactly what dose of ketamine i'm on » poser938

Posted by phidippus on April 20, 2012, at 18:08:10

In reply to Re: found out exactly what dose of ketamine i'm on, posted by poser938 on April 20, 2012, at 17:59:47

What antidepressants have you been on?

Eric

 

Re: found out exactly what dose of ketamine i'm on

Posted by poser938 on April 20, 2012, at 18:09:14

In reply to Re: found out exactly what dose of ketamine i'm on » poser938, posted by phidippus on April 20, 2012, at 18:04:54

heh... i think the closest one is in New York.
there arent really any ones that are close to my where i live.

 

Re: found out exactly what dose of ketamine i'm on

Posted by poser938 on April 20, 2012, at 18:23:24

In reply to Re: found out exactly what dose of ketamine i'm on » poser938, posted by phidippus on April 20, 2012, at 18:08:10

well, antidepressants and many other psychiatricsmeds have been the problem. doctors dont believe me about this, but when a med such as n antidepressant has its effect on my brain, the effect does not go away stopping the med. every now and then it will, but most of the time it is stuck with me.

i've had doctors tell me they dont believe me, or that im delusional and psychotic for thinking this.
but because of this, i am unable to function. before trying the meds, i had "mild depression" and could function very well. now i walk around dazed and confused and unable to feel many emotions other than feeling blank.

is it rally that hard to believe that every now and then, a person might come along and try antidepressants, and have them effect them differently than most? that the effects of the med could stick with them? doctors tell me this is impossible. that the severe mood changes i had while on meds such as mirapex or effexor were just random changes that werent caused by the med.
those were the worst 2 meds. i've tried others such as wellbutrin, prozac, zoloft, buspar, seroquel, risperdal, latuda, amisulpride tianeptine, ritalin, adderall.

they all had different effects on me except for zoloft having no effect on me. but when they change my brain, it is seemingly permanent.
meds like adderall made me feel sped up, that effect doesnt stick with me of course. but after taking it for a few weeks, it is as if it stimulates those receptors too much and tells me brain to stop producing dopamine by itself.


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