Psycho-Babble Medication Thread 993122

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Has anyone successfully treated anhedonia?

Posted by Economist on August 7, 2011, at 20:51:56

I've nearly exhausted the list of prescription drugs (currently on notriptyline 100 mg and Celexa 10 mg), and I'd like to try different supplements now.

My diagnosis is paranoid schizophrenia with prominent negative symptoms (anhedonia, amotivation, poverty of thought).

 

Re: Has anyone successfully treated anhedonia?

Posted by linkadge on August 7, 2011, at 21:26:22

In reply to Has anyone successfully treated anhedonia?, posted by Economist on August 7, 2011, at 20:51:56

Interesting that you are using two antidepressants for paranoid schizophrenia.

Hmm. I assume you've tried using antipsychotics? If the core diagnosis (schizophrenia) is not fully controlled, there may be some improvement with an AP. Seroquel might be an option (if you haven't tried) as it has a better track record for depression.

Omega-3 would be a decent addition, it can be good for certain cases of anhedonia. You could also try SAMe.

Linkadge


 

Re: Has anyone successfully treated anhedonia? » linkadge

Posted by Economist on August 7, 2011, at 21:58:30

In reply to Re: Has anyone successfully treated anhedonia?, posted by linkadge on August 7, 2011, at 21:26:22

I forgot to mention I'm on an antipsychotic, Abilify, too.

I'm taking fish oil now but I haven't tried SAM-e.


> Interesting that you are using two antidepressants for paranoid schizophrenia.
>
> Hmm. I assume you've tried using antipsychotics? If the core diagnosis (schizophrenia) is not fully controlled, there may be some improvement with an AP. Seroquel might be an option (if you haven't tried) as it has a better track record for depression.
>
> Omega-3 would be a decent addition, it can be good for certain cases of anhedonia. You could also try SAMe.
>
> Linkadge
>

 

Re: Has anyone successfully treated anhedonia? » Economist

Posted by Phillipa on August 7, 2011, at 23:49:37

In reply to Re: Has anyone successfully treated anhedonia? » linkadge, posted by Economist on August 7, 2011, at 21:58:30

Ever try Clozapine? I saw it work miracles when working in psych with schizophrenic patients. Just my observation. WBC counts are still weekly I guess. Phillipa

 

Re: Has anyone successfully treated anhedonia? » Economist

Posted by Shes_InItForTheMoney on August 8, 2011, at 7:11:52

In reply to Has anyone successfully treated anhedonia?, posted by Economist on August 7, 2011, at 20:51:56

> I've nearly exhausted the list of prescription drugs (currently on notriptyline 100 mg and Celexa 10 mg), and I'd like to try different supplements now.
>
> My diagnosis is paranoid schizophrenia with prominent negative symptoms (anhedonia, amotivation, poverty of thought).

You might want to get a few opinions about your diagnosis. Notriptyline seems a bizarre choice as it's monograph indicates it should not be used in anybody with the possibility of even the tinniest hint of an aggressive reaction. It can make schizophrenia much worse.

As far as what meds to take, you may have to try them all, then categorize which helped the best. Something with a norepinephrine component (for the drive), and a weaker serotonin med, plus benzos. Remember, all ssri's are NOT the same.
I know a client who seems to be doing well on a combo of prozac and effexor. He uses both at low doses, whereas before he couldn't tolerate effexor.

IMHO, etc,
Jay

 

Re: Has anyone successfully treated anhedonia?

Posted by Meddy43 on August 8, 2011, at 13:18:24

In reply to Re: Has anyone successfully treated anhedonia? » Economist, posted by Shes_InItForTheMoney on August 8, 2011, at 7:11:52

Have you tried different AAPs ?
Kindly, Meddy43

 

Re: Has anyone successfully treated anhedonia? » Economist

Posted by SLS on August 9, 2011, at 6:29:12

In reply to Has anyone successfully treated anhedonia?, posted by Economist on August 7, 2011, at 20:51:56

If you get stuck, you could try supliride or amisulpride. Each drug is a preferential dopamine D2 autoreceptor antagonist, and might be of more help for treating the Deficit Syndrome than other APs. Geodon can be activating, but it is not always a pleasant effect. Search the Internet for "deficit syndrome" (including quotation marks). It might explain residual anhedonia along with the other negative symptoms that persist.


- Scott


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