Psycho-Babble Medication Thread 922206

Shown: posts 1 to 3 of 3. This is the beginning of the thread.

 

Sigma-2 antagonists?

Posted by sowhysosad on October 24, 2009, at 9:18:52

Does anyone know of any drugs or, particularly, supplements that antagonise Sigma-2 receptors?

So far all I can come up with are Rimcazole and Ifenprodil.

One theory for EPS from uptake inhibitors is that they're caused by Sigma-2 agonism, so I thought it might be interesting to see whether symptoms are reduced by adding an antagonist.

 

Re: Sigma-2 antagonists?

Posted by Phidippus on October 25, 2009, at 2:03:53

In reply to Sigma-2 antagonists?, posted by sowhysosad on October 24, 2009, at 9:18:52

You found about the only two out there. There are a couple of other antagonists, but they are research drugs. Sigma-1 receptors are more widely programmed for ;)

 

Re: Sigma-2 antagonists? Phidippus

Posted by sowhysosad on October 25, 2009, at 10:24:02

In reply to Re: Sigma-2 antagonists?, posted by Phidippus on October 25, 2009, at 2:03:53

> You found about the only two out there. There are a couple of other antagonists, but they are research drugs. Sigma-1 receptors are more widely programmed for ;)

Thanks!

I guess I might just avoid uptake inhibitors in future.


This is the end of the thread.


Show another thread

URL of post in thread:


Psycho-Babble Medication | Extras | FAQ


[dr. bob] Dr. Bob is Robert Hsiung, MD, bob@dr-bob.org

Script revised: February 4, 2008
URL: http://www.dr-bob.org/cgi-bin/pb/mget.pl
Copyright 2006-17 Robert Hsiung.
Owned and operated by Dr. Bob LLC and not the University of Chicago.