Psycho-Babble Medication Thread 913518

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Re: Do all dopamine agonists have terrible withdra clipper40

Posted by Bob on August 22, 2009, at 18:16:01

In reply to Do all dopamine agonists have terrible withdrawals, posted by clipper40 on August 22, 2009, at 17:40:28

Dopamine agonists have terrible withdrawls?

 

Re: Do all dopamine agonists have terrible withdra

Posted by Sigismund on August 22, 2009, at 19:13:25

In reply to Re: Do all dopamine agonists have terrible withdra clipper40, posted by Bob on August 22, 2009, at 18:16:01

I took Trivastal for a while, certainly a few months, and never noticed a withdrawal syndrome.

I never took much. Half or 1 tablet a day. Good drug, French I believe.

 

Re: Do all dopamine agonists have terrible withdrawals

Posted by doxogenic boy on August 22, 2009, at 19:17:57

In reply to Do all dopamine agonists have terrible withdrawals, posted by clipper40 on August 22, 2009, at 17:40:28

> I'm probably going to be starting on Mirapex soon for RLS and I'm already worried about the horrible withdrawals I've read about with this drug. I believe that Requip has one as well. But what about Trivastal or any other dopamine agonists? If Trivastal or other medications are more benign in this respect, then I'd much rather try one of them first.
----------------------------------------------

There are other medications against RLS to try, if you don't want dopamine agonists. See Table 1:

http://www.movementdisorders.org/publications/ebm_reviews/treatmentofrls.pdf

doxogenic

 

Re: Do all dopamine agonists have terrible withdrawals clipper40

Posted by Phillipa on August 22, 2009, at 21:08:07

In reply to Do all dopamine agonists have terrible withdrawals, posted by clipper40 on August 22, 2009, at 17:40:28

Does lyrica help Restless Leg Sydrome as that is addictive. Phillipa Have a friend on low dose requip not for RLS but his miracle drug for depression with a few others at a very low dose.

 

Re: Do all dopamine agonists have terrible withdra Sigismund

Posted by bleauberry on August 23, 2009, at 16:13:47

In reply to Re: Do all dopamine agonists have terrible withdra, posted by Sigismund on August 22, 2009, at 19:13:25

> I took Trivastal for a while, certainly a few months, and never noticed a withdrawal syndrome.
>
> I never took much. Half or 1 tablet a day. Good drug, French I believe.

Why did you stop taking it?

I have tried it a couple times, just for a day at a time. Didn't feel much the day I took it. The next day though was usually a much better day than I was accustomed to feeling, and the following night was quite lousy sleep.

We don't hear much of this med, and I didn't want to derail this thread, but wanted to hear your story with Trivastal. If you don't mind sharing.

 

Re: Do all dopamine agonists have terrible withdra

Posted by clipper40 on August 23, 2009, at 16:48:44

In reply to Re: Do all dopamine agonists have terrible withdra clipper40, posted by Bob on August 22, 2009, at 18:16:01

From what I've read lately, yeah.

 

Re: Do all dopamine agonists have terrible withdra Sigismund

Posted by clipper40 on August 23, 2009, at 16:50:23

In reply to Re: Do all dopamine agonists have terrible withdra, posted by Sigismund on August 22, 2009, at 19:13:25

Good to know. I've considered this medication for a while now. It might be a better choice than Mirapex for me.

 

Re: Do all dopamine agonists have terrible withdrawals

Posted by clipper40 on August 23, 2009, at 16:51:13

In reply to Re: Do all dopamine agonists have terrible withdrawals, posted by doxogenic boy on August 22, 2009, at 19:17:57

Great link! Thanks.

 

Re: Do all dopamine agonists have terrible withdra bleauberry

Posted by Sigismund on August 23, 2009, at 17:00:49

In reply to Re: Do all dopamine agonists have terrible withdra Sigismund, posted by bleauberry on August 23, 2009, at 16:13:47

>but wanted to hear your story with Trivastal.

I took it for months, certainly. Just half or one tablet a day, first thing on waking, along with a little Hydergine and Valium. It made me feel a little bit nice, a sure sign that someone somewhere is thinking of banning it. No nausea from it, but if I'd upped the dose there might have been. Since I took it first thing on waking there was no more insomnia than normal, though it didn't help either. I didn't stop because it pooped out or turned nasty. I think agomelatine turned up.

 

Re: Do all dopamine agonists have terrible withdra

Posted by Sigismund on August 23, 2009, at 17:04:37

In reply to Re: Do all dopamine agonists have terrible withdra bleauberry, posted by Sigismund on August 23, 2009, at 17:00:49

>. Just half or one tablet a day,

And you can split the slow release tablets and nothing much happens to the rate of release.

Either that or piribedil agrees with me.

 

Re: Do all dopamine agonists have terrible withdrawals Phillipa

Posted by clipper40 on August 23, 2009, at 17:05:19

In reply to Re: Do all dopamine agonists have terrible withdrawals clipper40, posted by Phillipa on August 22, 2009, at 21:08:07

Yes, Lyrica and Requip are both used for RLS but they each have their issues. Most meds do unfortunately.

 

Re: Do all dopamine agonists have terrible withdra

Posted by cactus on August 25, 2009, at 23:13:21

In reply to Re: Do all dopamine agonists have terrible withdra bleauberry, posted by Sigismund on August 23, 2009, at 17:00:49

I was given ropinirole (Requip/Repreve) by my sleep doc. It literary works straight away. The other added bonus was it improved my depression out of this world. One problem though, it made me nauseated day and night, which I put up with for around 3 months because I felt so good. I couldn't get up to 2mg though, because I would vomit. So I stopped it cold turkey and had no side effects, withdrawal wise at all, except for instant funky legs again. Most of the stuff I read was people getting terrible augmentation from DA's, rebound RLS but worse while taking them, which defeats the purpose if you ask me but, WOW for depression!!

RLS.org is a good place for info if you haven't already read their boards.

I have found both diazepam and clonazepam to be the most effective for RLS. These will most likely cause withdrawal when stopped but if done properly, it should be ok.

Oxycodone and pure codeine, most opiates actually are good as well, but addictive too.

I use clonazepam now for multiple reasons so I don't have to worry about it at all anymore. Good luck.

 

Re: Do all dopamine agonists have terrible withdra cactus

Posted by clipper40 on August 26, 2009, at 0:31:06

In reply to Re: Do all dopamine agonists have terrible withdra, posted by cactus on August 25, 2009, at 23:13:21

Maybe you weren't on it long enough for withdrawal? I read that the more you take and the longer you take it, the worse the withdrawal problem. I think I was reading on this board of someone (Quintal?) having a bad withdrawal from Mirapex. Or maybe not everyone gets the withdrawal. I will have to do some more research.

Thanks for adding your RLS history. That was very helpful. I have been doing a lot of reading on the topic about treatment for this issue. (Yes, RLS.org is a great resource.) I would love it if the medication worked on my depression as well (without nausea). What a bonus that would be!

Currently I'm taking Xanax every third night. I'm not dependent on it at this point but I have still needed to up the dosage for benefit. This makes me believe that a benzo probably wouldn't be the way to go for me. Also, clonazepam doesn't agree with me. Makes me too groggy and depressed.

The opiates and tramadol will be last choice. At this point, though, anything that will allow me to sleep sounds good. My doctor's appointment is tomorrow so hopefully I'll get some relief soon.

Do you take anything besides the clonazepam?

 

Re: Do all dopamine agonists have terrible withdra clipper40

Posted by cactus on August 26, 2009, at 23:50:07

In reply to Re: Do all dopamine agonists have terrible withdra cactus, posted by clipper40 on August 26, 2009, at 0:31:06

Ok if clonazepam doesn't agree with you then I'd try valium, it's another fantastic option. I'm actually glad the ropinirole didn't work out for me because of the nausea, the rebound RLS seems to get most people in the end on either mirapex or requip/repreve, and it sounds quite nasty if you're unlucky enough for it to happen to you.

I know 3 months isn't that long but I've had terrible withdrawals from SSRI's after that amount of time, everyone is different I suppose. It's funny you take xanax for it. I didn't know it was used for it. Saying that, xanax is the only benzo I had hell getting off. All the others were fine, but xanax did a number on me, which is a shame because it does have AD properties in my opinion, well for me it did anyway.

I'm currently on:
10mg Edronax (Reboxetine) 6mg AM 4mg PM
3x2mg of Rivotril (clonazepam)
75mg of Lamictal, soon to be 100mg
5mg Mogadon (nitrazepam) PRN

Still struggling with the depression big time at the moment but I'm prepared to give the Edronax-Lamictal combo a really good go. I'm running out of options and my pdoc mentioned Parnate last visit which I really don't want to try due to insomnia, which I have suffered from since my teens and OSA too. The list goes on.

Anyway, I hope you got this before you went to your doc. I'm in Australia so the time difference might work out well if you're in North America, I'd go the Valium 1st but that's between you and your doc, good luck.

PS. anyone out there who hasn't got RLS, I'd seriously consider a DA if you can stomach it.

Peace C

 

Re: Do all dopamine agonists have terrible withdra cactus

Posted by clipper40 on August 27, 2009, at 2:39:53

In reply to Re: Do all dopamine agonists have terrible withdra clipper40, posted by cactus on August 26, 2009, at 23:50:07

My doctor gave me a script for Neurontin. That surprised me as I expected Mirapex. I don't want to take any of the meds that are used to treat RLS but I've just got to get some sleep.

I know what you mean about medications used to treat one condition being contraindicated for another condition you have. It's all so complicated some times. I do hope that the Edronax/Lamictal combo works out for you.

 

Re: Do all dopamine agonists have terrible withdra clipper40

Posted by cactus on August 27, 2009, at 5:01:18

In reply to Re: Do all dopamine agonists have terrible withdra cactus, posted by clipper40 on August 27, 2009, at 2:39:53

yeah me too and I hope the neurontin works out for you!! All the best. C

 

Re: Do all dopamine agonists have terrible withdra

Posted by Brainbeard on August 27, 2009, at 11:08:07

In reply to Re: Do all dopamine agonists have terrible withdra Sigismund, posted by bleauberry on August 23, 2009, at 16:13:47

I've been taking piribedil (Trivastal) for the last month. When I skip a dose, I'm more prone to depression. I take 50mg XR in the morning, though I started taking it at bedtime. The drug has a subtle effect for me. It kicks in with a buzz so mild that it can easily go unnoticed. After that, it seems to intensify moments of happiness. Which isn't a bad thing. I definitely don't hope piribedil would have a withdrawal syndrome, since the drug is a little bit too expensive for my liking.

And yes, it's French. Yet another against-the-grain product of secretive (according to David Pearce's Healthy Mood-Boosters Guide) Servier.

 

Re: Do all dopamine agonists have terrible withdra Brainbeard

Posted by Bob on August 27, 2009, at 11:33:45

In reply to Re: Do all dopamine agonists have terrible withdra, posted by Brainbeard on August 27, 2009, at 11:08:07

> I've been taking piribedil (Trivastal) for the last month. When I skip a dose, I'm more prone to depression. I take 50mg XR in the morning, though I started taking it at bedtime. The drug has a subtle effect for me. It kicks in with a buzz so mild that it can easily go unnoticed. After that, it seems to intensify moments of happiness. Which isn't a bad thing. I definitely don't hope piribedil would have a withdrawal syndrome, since the drug is a little bit too expensive for my liking.
>

I assume that Trivastal is not available in the US?

 

Re: Do all dopamine agonists have terrible withdra Sigismund

Posted by Bob on August 27, 2009, at 11:36:12

In reply to Re: Do all dopamine agonists have terrible withdra, posted by Sigismund on August 22, 2009, at 19:13:25

> I took Trivastal for a while, certainly a few months, and never noticed a withdrawal syndrome.
>
> I never took much. Half or 1 tablet a day. Good drug, French I believe.

Is this drug know for the 'sleep attacks' like Mirapex?

 

Re: Do all dopamine agonists have terrible withdra Brainbeard

Posted by clipper40 on August 27, 2009, at 14:36:43

In reply to Re: Do all dopamine agonists have terrible withdra, posted by Brainbeard on August 27, 2009, at 11:08:07

I hadn't heard that Servier is secretive. Why does Dave Pearce call it that?

Please keep us posted about how you continue to do on Trivastal. I think that may be a better drug for me than Neurontin.

 

Re: Also

Posted by clipper40 on August 27, 2009, at 15:03:38

In reply to Re: Do all dopamine agonists have terrible withdra, posted by Brainbeard on August 27, 2009, at 11:08:07

I read on another post that you're taking tianeptine now. So you're taking that with the Trivastal? If so, do you find that they go together well? Any issues with the combination?
Are you taking anything else now?

 

Re: Also

Posted by Sigismund on August 27, 2009, at 17:24:27

In reply to Re: Also, posted by clipper40 on August 27, 2009, at 15:03:38

>Is this drug know for the 'sleep attacks' like Mirapex?

No, if anything it is stimulating, but not unpleasantly so.

I've never taken Mirapex.

 

Re: Also [About piribedil (Trivastal)]

Posted by Brainbeard on August 28, 2009, at 6:29:22

In reply to Re: Also, posted by clipper40 on August 27, 2009, at 15:03:38

Trying to answer everyone:

I guess Trivastal (piribedil) is not available in the US, I don't know. It can be bought over the internet, but it's not cheap.

Trivastal seems to be the least likely non-ergot dopamine agonist to cause sleep attacks. I think I saw a research abstract where a couple of folks had a sleep attack on it, but they were Parkinsonians to begin with. If not for the sleep attacks, I might have tried Mirapex (pramipexole), but I don't wanna end up crashing my daughter into a car when we're making a ride on the bike.

I don't know why Dave Pearce calls Servier 'secretive'. He speaks of 'secretive, privately-owned Servier, the innovative French drug giant.' He is the kind of guy who does his homework, though.

I think tianeptine goes together well with piribedil (Trivastal). I can't say though that I've noticed any explicit synergy. But I'm taking other meds as well.

Currently, I'm also on 25mg of sertraline (Zoloft), 20-30mg of ziprasidone (Geodon), 15-40mg of Buspar and I have been taking 10mg of selegiline for a while together with some tianeptine when I felt like it and of course a little bit of modafinil (50mg). I take some Ativan (lorazepam) as needed, which has become a lot more often than I'd like recently since I'm suffering from panic attack-like stuff and from general anxiety as well as obsessive fears.

Unfortunately, I have to break the news to you that I think of quitting Trivastal for now, as well as modafinil and selegiline and tianeptine, simply because I don't have much money at this time. And I'm entering a daytime treatment program where they're gonna try and stop me doing my self-medication.

By the way, as far as doses go, keep in mind that I'm always experimentating.

 

Re: Also [About piribedil (Trivastal)]

Posted by clipper40 on August 29, 2009, at 2:25:10

In reply to Re: Also [About piribedil (Trivastal)], posted by Brainbeard on August 28, 2009, at 6:29:22

Thanks for all of that info. Sounds like it might be a good idea to cut back on some of the meds and enter that program. I hope it works out for you.

 

Re: Also [About piribedil (Trivastal)]

Posted by Brainbeard on August 29, 2009, at 4:33:49

In reply to Re: Also [About piribedil (Trivastal)], posted by clipper40 on August 29, 2009, at 2:25:10

> Thanks for all of that info. Sounds like it might be a good idea to cut back on some of the meds and enter that program. I hope it works out for you.
>
>

Thanks, Clipper.


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