Psycho-Babble Medication Thread 912232

Shown: posts 1 to 17 of 17. This is the beginning of the thread.

 

How Does Remeron Work For You All?

Posted by Rdragon on August 15, 2009, at 9:52:07

I'm going to try Remeron next because I really want something that is POTENT at stopping depression in its tracks. (Prozac is the weakest SSRI) I've been reading about it and I'm confused as to how it exactly works. I know it isn't an SSRI or SNRI, but does it raise serotonin and norepinphrine as potently as the SSRI's and SNRI's? The efficacy of it seems extremely good in the studies of it versus SSRI's/SNRI's.

Also how is everyone doing on Remeron? Mood-wise, sleep-wise, just in general?

 

Re: How Does Remeron Work For You All? ╗ Rdragon

Posted by Phillipa on August 15, 2009, at 10:40:11

In reply to How Does Remeron Work For You All?, posted by Rdragon on August 15, 2009, at 9:52:07

My experience with remeron was 30 days at 15mg for sleep. It didn't make me sleepy but so many here find it a wonderful med for sleep. I seriously thought prozac was the strongest of the SSRI's with luvox being the weakest? Love Phillipa

 

Re: How Does Remeron Work For You All? ╗ Rdragon

Posted by Maxime on August 15, 2009, at 12:16:03

In reply to How Does Remeron Work For You All?, posted by Rdragon on August 15, 2009, at 9:52:07

All it did for me was make me eat like a horse and sleep. I had to stop it because I couldn't function. I hope you have better luck with it.

 

Re: How Does Remeron Work For You All? ╗ Rdragon

Posted by sowhysosad on August 15, 2009, at 14:12:37

In reply to How Does Remeron Work For You All?, posted by Rdragon on August 15, 2009, at 9:52:07

Utterly useless as an AD on its own, although some find it useful as an add-on to SSRI/NI's to help with sleep and anxiety.

 

Re: How Does Remeron Work For You All? ╗ Rdragon

Posted by johnj1 on August 15, 2009, at 21:30:02

In reply to How Does Remeron Work For You All?, posted by Rdragon on August 15, 2009, at 9:52:07

I was on remeron for a few years in the past. I felt like it robbed me of myself. I am still trying to repair relationships that were hurt by me being on the drug. It made my OCD worse, made me angry and I would punch things (not people) when I got angry. I stayed on it for sleep only and that was a very bad idea. Towards the end of being on it it made depression much worse. Getting off was hell too. If you want to look in the archives on remeron withdrawal you will find that many people had a very hard time getting off of it. Good luck.

johnj

 

Re: How Does Remeron Work For You All?

Posted by X-ray on August 16, 2009, at 12:07:02

In reply to How Does Remeron Work For You All?, posted by Rdragon on August 15, 2009, at 9:52:07

Hi,

I switched from amitriptyline to mirtazapine last year,
but now I'm back on amitriptyline.

The big problem about mirtazapine is drowsiness.
I just barely got enough sleep while I was on this drug.

I didn't feel rested in the daytime.
I was tired and had a problem to concentrate on my work.

So I would like to add another drug to mirtazapine for better sleep.

I'm thinking about trying Seroquel or Lyrica,
but I have to play it safe for the time being.

So I'll stick to amitriptyline and buspirone.

However, mirtazapine is a modern drug that has few side effects.
So this drug might be just right for you.

Best regards,
X-ray

 

Re: How Does Remeron Work For You All?

Posted by Alexanderfromdenmark on August 16, 2009, at 12:38:13

In reply to How Does Remeron Work For You All?, posted by Rdragon on August 15, 2009, at 9:52:07

> I'm going to try Remeron next because I really want something that is POTENT at stopping depression in its tracks. (Prozac is the weakest SSRI) I've been reading about it and I'm confused as to how it exactly works. I know it isn't an SSRI or SNRI, but does it raise serotonin and norepinphrine as potently as the SSRI's and SNRI's? The efficacy of it seems extremely good in the studies of it versus SSRI's/SNRI's.
>
> Also how is everyone doing on Remeron? Mood-wise, sleep-wise, just in general?

For me it was a mixed experience. I only tried it for 2,5 weeks. It was one of the first AD's i tried. it gave me RLS and 30 mg, but after that made me sleep well. Almost impossible to get up the next day. It's definitely a more powerfull drug than most ssriĘs. It gave me somwhat remession a few hours a day, but it's also sometimes made me very sedated and during the end on of the trial very irritable, agressive and panicky. I wish I'd given a month at least. I quite like the stimulation of appetite it gave me sometimes. I'd recommend giving it a trial of 6 weeks starting at 30 mg. Anything less it too sedaing. Due to it's pro sleeping and anti-anhedonia effects I think it holds more chance of remession than SSRI's. give it 4-6 weeks and you will either love it or hate it.

 

Re: How Does Remeron Work For You All?

Posted by bleauberry on August 17, 2009, at 16:52:17

In reply to How Does Remeron Work For You All?, posted by Rdragon on August 15, 2009, at 9:52:07

How Does Remeron Work For You All?

Like poison. Takes a moderately bad depression and turns it into severe.

 

Re: How Does Remeron Work For You All?

Posted by SLS on August 17, 2009, at 17:51:11

In reply to Re: How Does Remeron Work For You All?, posted by bleauberry on August 17, 2009, at 16:52:17

> How Does Remeron Work For You All?
>
> Like poison. Takes a moderately bad depression and turns it into severe.

Or, it takes a severe depression and turns it even more severe. I think some people just don't react well to NE alpha2 receptor antagonists. There are, however, real people who report doing well on Remeron. For now, I can't see any doctor turning to Remeron as their first choice to treat depression.


- Scott

 

Re: How Does Remeron Work For You All? ╗ SLS

Posted by Phillipa on August 17, 2009, at 21:31:08

In reply to Re: How Does Remeron Work For You All?, posted by SLS on August 17, 2009, at 17:51:11

Another neutral med for me why is luvox the only ad that affects me at all as brain seems to need it. If it's in the middle of SSRI's what other SSRI's are similar in strength? Love Phillipa

 

Re: How Does Remeron Work For You All? ╗ Phillipa

Posted by SLS on August 18, 2009, at 5:27:35

In reply to Re: How Does Remeron Work For You All? ╗ SLS, posted by Phillipa on August 17, 2009, at 21:31:08

> Another neutral med for me why is luvox the only ad that affects me at all as brain seems to need it. If it's in the middle of SSRI's what other SSRI's are similar in strength? Love Phillipa

Zoloft and Paxil seem to be the "strongest". I think Prozac is the "weakest". Celexa, Lexapro, and Luvox are somewhere in the "middle".

These represent the binding affinity (dissociation constant) of the drug to the receptor on the 5-HT transporter. They do not represent effectiveness. Prozac, being weaker than Luvox, is still, in my opinion, a more potent drug to treat depressive disorders. Luvox is, however, the most efficacious for treating OCD. In vitro binding affinities alone must therefore not be the whole story as to how these drugs work.


- Scott

 

Re: How Does Remeron Work For You All?

Posted by zana on August 18, 2009, at 9:13:22

In reply to Re: How Does Remeron Work For You All? ╗ Phillipa, posted by SLS on August 18, 2009, at 5:27:35

I don't know what remeron is doing for me since I am taking it with so many other meds but it is a great sleep med for me even at 45mg which is the range when it is supposed to be more stimulating than sedating. It is also supposed to be a good med to combine with pristiq which I am also taking.

Zana

 

Re: How Does Remeron Work For You All? ╗ bleauberry

Posted by g_g_g_unit on August 18, 2009, at 17:46:21

In reply to Re: How Does Remeron Work For You All?, posted by bleauberry on August 17, 2009, at 16:52:17

> How Does Remeron Work For You All?
>
> Like poison. Takes a moderately bad depression and turns it into severe.

i was going to post a new thread on this subject, but feel like my question would be equally suitable here.

are you - or anyone else - aware of Remeron's mechanism of action, specifically how it would increase anxiety at doses above 15mg?

at 30mg i experienced the most nightmarish exacerbation of my anxiety + OCD symptoms; for some reason (paralyzed by fear?) i remained on that dose for a week before pulling the plug. i've been mentally reviewing my med history these past few days, and shortly after d/c remeron is the first time i can recall complaining to my pdoc that i felt 'foggy'. have never felt the same since. i'm wondering if the excrutiating anxiety was enough to finally blow my adrenals or something

 

Re: How Does Remeron Work For You All? ╗ SLS

Posted by Phillipa on August 18, 2009, at 20:24:12

In reply to Re: How Does Remeron Work For You All? ╗ Phillipa, posted by SLS on August 18, 2009, at 5:27:35

Scott paxil seemed much stronger to me. Zoloft weak, prozac flipped me out in three days when first out at 20mg. Wasn't depressed then. Just an experiment by a pdoc. Phillipa and thanks for answering

 

Re: How Does Remeron Work For You All?

Posted by Zena on August 20, 2009, at 13:40:03

In reply to Re: How Does Remeron Work For You All? ╗ SLS, posted by Phillipa on August 18, 2009, at 20:24:12

I have been on 15mg. Remeron & 10mg. lexapro for 6 yrs.My only issue with Remeron is weight gain. I really have to watch that.It's wonderful for sleep. These two have worked great for me. I think you have to have a SSR along with the Remeron. I found that to be true in my case.
Zena

 

Re: How Does Remeron Work For You All?

Posted by rick alan s on August 20, 2009, at 16:59:47

In reply to How Does Remeron Work For You All?, posted by Rdragon on August 15, 2009, at 9:52:07

Well, i was looking this over. I have just been prescribed Remeron after 25 years on Parnate. I stopped the Parnate after a hypertensive crisis ( and have been very depressed during the 18 days without Parnate. So I have been on Remeron for two days, taking only half of a 15 mg pill. In any case, I just wanted to get involved in the discussion. I don't have a lot to contribute to the question as to how does Remeron work for me, because I have just begun with Remeron.

What would work for me would also be having a good challenging job (I am currently running a small business to earn enough money to live on, but it takes up very little time, and I have too much free time, and feel very under-challenged). And a better support network. I live out of the USA and sometimes feel very isolated here in Costa Rica, even after 20 years. Its a long story as to how I wound up here, and why I am still here. In any case for me, the depression is always interactive with real life issues, but when I have had depressions in the past they have been severe. Parnate previously was what had worked for me.

As a parenthesis I would add (although it is not politically correct, perhaps) that I began taking Vicodin for a physical problem resulting in pain, about seven years ago. I also find now that a small amount of Vicodin (half of a 5/500 pill) takes the edge off of the depression. I am not thrilled about doing this, but at the moment I have found that this helps during this transition between Parnate and Remeron, and I don't feel like I am an "addict". In any case, I have never taken more than two Vicodin per day, and have tried very hard not to develop tolerance avoid 'addiction' in the traditional sense.
any feed back is welcome
Rick in Costa Rica

 

Re: How Does Remeron Work For You All?

Posted by zzzz7 on September 7, 2009, at 19:49:42

In reply to Re: How Does Remeron Work For You All?, posted by Zena on August 20, 2009, at 13:40:03

I'm a strange case; I can't take more than 1mg of an SSRI or of something like Wellbutrin without becoming incredibly depressed.

Remeron I have been able to take in something close to therapeutic doses--7.5mg. And my depression is 50% better than it was before taking it. 15mg causes me to crash; I suspect it's the increased NE activity.


This is the end of the thread.


Show another thread

URL of post in thread:


Psycho-Babble Medication | Extras | FAQ


[dr. bob] Dr. Bob is Robert Hsiung, MD, bob@dr-bob.org

Script revised: February 4, 2008
URL: http://www.dr-bob.org/cgi-bin/pb/mget.pl
Copyright 2006-17 Robert Hsiung.
Owned and operated by Dr. Bob LLC and not the University of Chicago.