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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 9 of 9. This is the beginning of the thread.
Posted by Rdragon on June 27, 2009, at 10:57:01
I have absolutely no motivation right now and this is a serious problem for me. I am on geodon and prozac, and I believe it is the geodon which is causing the loss of motivation. I am on the geodon for anxiety/depression, and it definitely seems to do something for me, which is better than nothing, so I'm keeping it. I was thinking about adding Mirapex to my combo of meds, would it make the geodon less effective though since they're working against each other? Anyone know in general some good meds that are good for motivation and don't increase your anxiety?
Posted by Alexanderfromdenmark on June 27, 2009, at 13:56:06
In reply to Meds for Motivation, posted by Rdragon on June 27, 2009, at 10:57:01
> I have absolutely no motivation right now and this is a serious problem for me. I am on geodon and prozac, and I believe it is the geodon which is causing the loss of motivation. I am on the geodon for anxiety/depression, and it definitely seems to do something for me, which is better than nothing, so I'm keeping it. I was thinking about adding Mirapex to my combo of meds, would it make the geodon less effective though since they're working against each other? Anyone know in general some good meds that are good for motivation and don't increase your anxiety?
If I were you i'd rather lose the meds instead of adding a third. but that's just me. For me 2 meds are max, 3 is definitely pushing it.
Posted by bleauberry on June 27, 2009, at 15:07:59
In reply to Meds for Motivation, posted by Rdragon on June 27, 2009, at 10:57:01
I agree with the previous post. Three meds might be warranted for really bad cases. The fact that you lack motivation does not mean you need yet another drug, it means the ones you are taking are less than satisfactory. That said, the meds I would consider adding if you want to pile on more are Modafinil (brand), nortriptyline (low dose) or desipramine (low dose).
Any serotonin med without a noradrenergic partner is very likely to cause the lack of motivation thing. Prozac by itself is highly suspect in that regard. All atypicals commonly have a blunting effect to them, so the geodon is working against you in the motivation department as well. That's how I see it anyway. I know I know, someone is going to say but geodon has action on norepinephrine. Whatever. It aint the right kind of action and not strong enough. Opinion.
The one I think lacks that anti-motivation thing the most is zyprexa, most especially in combination with prozac. When I was on those two, motivation improved a lot, but still fell short until I added a small amount of Modafinil.
Ditch the geodon. Small dose zyprexa, nortriptyline or desipramine or modafinil. Those are the things I would be looking at. Just my 2 cents for whatever it's worth.
The noradrenergic TCAs like nortiptyline are actually very good for anxiety and social comfort after getting through the activating start up days.
Posted by bladewalker on June 27, 2009, at 16:24:44
In reply to Meds for Motivation, posted by Rdragon on June 27, 2009, at 10:57:01
try to switch GEODON to low dose(2-5mg)of ABILIFY, should do same bit for dep/anx as geodon + motivation UP
Posted by Rdragon on June 27, 2009, at 21:29:52
In reply to Re: Meds for Motivation, posted by bleauberry on June 27, 2009, at 15:07:59
> I agree with the previous post. Three meds might be warranted for really bad cases. The fact that you lack motivation does not mean you need yet another drug, it means the ones you are taking are less than satisfactory. That said, the meds I would consider adding if you want to pile on more are Modafinil (brand), nortriptyline (low dose) or desipramine (low dose).
>
> Any serotonin med without a noradrenergic partner is very likely to cause the lack of motivation thing. Prozac by itself is highly suspect in that regard. All atypicals commonly have a blunting effect to them, so the geodon is working against you in the motivation department as well. That's how I see it anyway. I know I know, someone is going to say but geodon has action on norepinephrine. Whatever. It aint the right kind of action and not strong enough. Opinion.
>
> The one I think lacks that anti-motivation thing the most is zyprexa, most especially in combination with prozac. When I was on those two, motivation improved a lot, but still fell short until I added a small amount of Modafinil.
>
> Ditch the geodon. Small dose zyprexa, nortriptyline or desipramine or modafinil. Those are the things I would be looking at. Just my 2 cents for whatever it's worth.
>
> The noradrenergic TCAs like nortiptyline are actually very good for anxiety and social comfort after getting through the activating start up days.The problem with the noradrenaline is that me and that chemical do NOT have a pleasant relationship. For years I suffered with crippling anxiety until Paxil came along and annihilated it. I theorize that I had way too much noradrenaline and not nearly enough serotonin.
I'd rather go with something that raises my dopamine like Mirapex.
And I think that bladewalkers post about going onto Abilify actually sounds like a great idea. I WAS on abilify, at 20mg, and it DEFINITELY was better for my motivation. I think I'm going to ask for a raised dosage to maybe 40mg.
Posted by Phillipa on June 27, 2009, at 21:57:58
In reply to Re: Meds for Motivation, posted by Rdragon on June 27, 2009, at 21:29:52
Isn't that a high dose of abilify? Phillipa
Posted by Rdragon on June 27, 2009, at 22:11:09
In reply to Re: Meds for Motivation » Rdragon, posted by Phillipa on June 27, 2009, at 21:57:58
> Isn't that a high dose of abilify? Phillipa
Yeah it is, but we started me off on 5mg, then slowly worked are way to 20. I think we could've seen more improvements had we increased it to 40. So what I plan on doing is going back to Lexapro, going back to abilify, and starting lithium. So thats 3 meds, which is the absolute max I'm willing to go.
Posted by morganpmiller on June 27, 2009, at 22:15:25
In reply to Re: Meds for Motivation, posted by Rdragon on June 27, 2009, at 22:11:09
Good luck
Posted by floatingbridge on June 28, 2009, at 12:34:47
In reply to Re: Meds for Motivation, posted by bleauberry on June 27, 2009, at 15:07:59
I add my two cents to Bleauberry's. Is the geodon (sp) for bi-polar?
I am liking my first week on provigil--doesn't seem to distort my personality, whatever that is!
This is the end of the thread.
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