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Dr. Bob is Robert Hsiung, MD,
dr-bob@uchicago.eduShown: posts 1 to 3 of 3. This is the beginning of the thread.
Posted by Mishal on September 23, 2007, at 4:56:19
Can anyone explain this to me please?I like Provigil, and my dosage is 200mg in the morning. But by the evening I crash and sink into depression. I tried to overcome this by taking an extra 100mg in the evening, but couldn't sleep then even on Ambien.
Then I added Atarax (Hydroxyzine) and surprisingly, I didn't crash in the evening time. But Atarax was too much sedating for me, so I tried clomipramine which was with me. Still surprisingly, while I was on clomipramine I didn't crash in the evening as usual.
The thing that is common in Atarax and Anafranil is their anticholinergic effects. Does anticholinergics prevent Provigil crash?
Posted by linkadge on September 23, 2007, at 9:45:34
In reply to Provigil crash: can anticholinergics help?, posted by Mishal on September 23, 2007, at 4:56:19
Possably. Atarax is also a MAO-B inhibitor (believe it or not) in addition to an antihistamine. The common function may have been some sort of monoamine modulation. Or perhaps like you say anticholinergic activity.
Linkadge
Posted by Phillipa on September 23, 2007, at 11:53:28
In reply to Re: Provigil crash: can anticholinergics help?, posted by linkadge on September 23, 2007, at 9:45:34
Link what's benadryl then as both were used depending on the doc when I worked? for any allergic type condition itching. Phillipa
This is the end of the thread.
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