Psycho-Babble Medication Thread 695041

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Seroquel Hangover- anyone else taking high doses?

Posted by Lindenblüte on October 15, 2006, at 13:56:57

Hi All,
in the last 10 days I have gradually increased my seroquel dose from 50 to 300 mg.

It's SOOOO hard to peel my eyelids open in the am. I take provigil 200mg as soon as I get up, but I still feel like I have an oatmeal brain. Kind of like a hangover without the nausea.

Pdoc said it might take a week OR SO to get over this. I never had a problem with daytime fatigue on 50mg of seroquel.

Anyone with any experiences on these doses of seroquel?

P.S. taking it for intrusive thoughts and flashbacks and nightmares, and for antidepressant augmentation and mood stabilization.

 

Re: Seroquel Hangover- anyone else taking high doses? » Lindenblüte

Posted by Phillipa on October 15, 2006, at 15:44:24

In reply to Seroquel Hangover- anyone else taking high doses?, posted by Lindenblüte on October 15, 2006, at 13:56:57

The biggest question is it helping more at 300mg than the lower dose? And can you join the world in a while? Love Phillipa

 

Can I ask you

Posted by Declan on October 15, 2006, at 16:07:04

In reply to Seroquel Hangover- anyone else taking high doses?, posted by Lindenblüte on October 15, 2006, at 13:56:57

how effective you are finding it for mood stabilization and possible AD effect?

What's mood stabilisation anyway? Avoiding black holes and stuff? OK, I do have good moods now and again.

 

Re: Can I ask you » Declan

Posted by Lindenblüte on October 15, 2006, at 19:55:20

In reply to Can I ask you, posted by Declan on October 15, 2006, at 16:07:04

hmm well, I felt pretty 'down' this am. forced myself to get off babble and go to cafe and do 2 hours of work. felt pretty depressed, not tired, just down. then I started getting antsy- people in the cafe started annoying me- I couldn't ignore any of the 12 conversations going on around me. I took off. went to walgreens. special on ricola. i bought that and a new nailpolish, and some coffee creamer, so that i won't have to go to cafe tomorrow to wake up.

I don't know why, but when I got home at 4pm, I had a great burst of energy. cleaned my kitchen, even emptied and reorganized my cabinet of tupperware, my cookbooks, and my little zoo of kitchen appliances. wiped the countertops. did all kinds of good deeds for my home!

now I feel fine. but the hangover lasted until about 3pm.

mood stabilization- pretty good. I haven't felt a major surge of rage or grief in several days. (I've been going up from 100-300mg over 10 days, only hitting 300 yesterday).

OMG!!! THE freaking cymbalta commercial is on dammit!! LOL

see- my mood is stabilized. usually I'm laughing hysterically at this commercial.

AD effect?- no, actually, I've felt more depression since I changed my meds 2 weeks ago. Could this be due to benzodiazepine? possibly.

My suicidal thoughts are greatly decreased, however, as are many other kinds of intrusive thoughts, flashbacks, anxiety attacks, and dissociative symptoms.

-Li

 

Re: Can I ask you » Lindenblüte

Posted by Phillipa on October 15, 2006, at 21:43:14

In reply to Re: Can I ask you » Declan, posted by Lindenblüte on October 15, 2006, at 19:55:20

Li no I don't think that small a dose of klonopin would depress you. But remember you've made a lot of med changes in a short time. I'm so glad the seroquel is working for you. And that you got that burst of energy. Hope tomorrow is good too. And you have your coffee supplies on hand. Love Phillipa

 

Re: Can I ask you

Posted by Lindenblüte on October 15, 2006, at 22:01:24

In reply to Re: Can I ask you » Lindenblüte, posted by Phillipa on October 15, 2006, at 21:43:14

Thanks Phillipa,
I don't know if it's klonopin or seroquel or some combination of my fancy polypharmacy cocktail. I have always been so sensitive to my mood changes and to pain, and to other people's emotions. Maybe I'm just one big raw nerve ending?

Well, I feel great now. Maybe I should rearrange my schedule so that I wake up at 3am, and go to bed at 6pm. no, that would not be fun.

Maybe I should take provigil at 6am, be awake at 6:30 and work from 8-5. That would be impressive. then I can go to bed at 9pm. wow. And I should train for a marathon while I'm at it.

whatever.

Seriously, I know over half the babblers here will find this completely irrelevant, but do other people prone to depression get breakthrough depression in their PMenstr. or other parts of their cycle? This is not the first month I've noticed it. I just never had such a strong change before.

Gute Nacht an Alle
Eure,
Lindenblüte

 

Re: Can I ask you

Posted by alexandra_k on October 15, 2006, at 23:52:21

In reply to Re: Can I ask you, posted by Lindenblüte on October 15, 2006, at 22:01:24

i used to take 250mg BD (2X daily)

i was on a whole cocktail though.
epilim too.

and 2X imovane for sleep.

i think the seroquel was pretty good.

seroquel epilim combo worked pretty good.

seroquel for the stress induced psychotic thing
epilim for mood stabilisation

yes your depression could be due to the benzo

i would say more likely that than the seroquel

seroquel does have a sedative effect though

i'm always knocked on it for a week to a week and a half while i adjust

i used to be fairly resistent to med changes, meds hardly seemed to affect me but that was when i was having time off uni

now that i'm at uni and it is important for me to be on the ball i do indeed notice a drugged effect. i started 25mg and felt so drugged... i stopped taking it after 2 days.

if the depression / glugginess is really worrying you...
i'd stop the benzo and give yourself a week to adjust to the seroquel

if things get worse you can always reevaluate.

 

Re: Can I ask you » alexandra_k

Posted by Lindenblüte on October 16, 2006, at 8:36:21

In reply to Re: Can I ask you, posted by alexandra_k on October 15, 2006, at 23:52:21

That's good advice Alex,
I took benzo am and pm (.5mg each time) for 4 days,
then emailed pdoc, who said maybe only in the am, and prn if I need it (have needed it twice in the afternoon)

I am going into dissertation retreat (that means getting away from the uni, and travelling to stay with my husband, who is in the military- no classes, no meetings, pleasant distractions, and some physical exercise)

I think that this will be a good time for me to explore taking a half tablet daily, or perhaps even a half tablet prn. My pdoc seems pretty open to letting me do my own experiments on the provigil and the klonopin, as long as they are gradual changes, and I keep him abreast of any adverse reactions.

Thanks for your ideas. It means a lot to me that you think of me when you're having such a hard time yourself. I really hope that you can get some folks working on your case. Try to stay around other people. If you can go to class, just to keep some kind of regular schedule, it might help. Even if you have to bring some colored pens, and sit in the way back and doodle, at least you'll be keeping your routine.

(((((Alexandra)))))

 

Re: Can I ask you » alexandra_k

Posted by Phillipa on October 16, 2006, at 18:20:19

In reply to Re: Can I ask you, posted by alexandra_k on October 15, 2006, at 23:52:21

Alex not criticism but twice a day is BID. That's for future reference. A learning experience. Love Phillipa

 

Re: Can I ask you

Posted by exquilter on October 16, 2006, at 21:24:21

In reply to Re: Can I ask you, posted by Lindenblüte on October 15, 2006, at 22:01:24

I had PMS problems, usually depression, even when meds were helping otherwise. I had to pay close attention to my calendar so I didn't freak unnecessarily, fortunately my cycle was pretty predictable when I was younger.

Exquilter

 

Re: Seroquel Hangover- anyone else taking high dos

Posted by yxibow on October 17, 2006, at 2:09:15

In reply to Seroquel Hangover- anyone else taking high doses?, posted by Lindenblüte on October 15, 2006, at 13:56:57

> Hi All,
> in the last 10 days I have gradually increased my seroquel dose from 50 to 300 mg.
>
> It's SOOOO hard to peel my eyelids open in the am. I take provigil 200mg as soon as I get up, but I still feel like I have an oatmeal brain. Kind of like a hangover without the nausea.
>
> Pdoc said it might take a week OR SO to get over this. I never had a problem with daytime fatigue on 50mg of seroquel.
>
> Anyone with any experiences on these doses of seroquel?
>
> P.S. taking it for intrusive thoughts and flashbacks and nightmares, and for antidepressant augmentation and mood stabilization.


Whew.. I've taken it up to 1200mg. I take it at 800mg currently for a non psychotic complex disorder, if that is any comparison of a high dose.

I once accidentally mistook it for another medication and I had a social meeting with someone , I was on 1600mg basically of it, I felt like a dork but managed to get home.


Seroquel is the most sedating of all antipsychotics, including non atypicals. But I take it because it has the least EPS which I am sensitive to and the lowest risk of TD. I would never take neuroleptics but for this rare disorder I'm fighting.


But back to business.. yes, over time you get used to the fatigue, but from what I've learned, taking the Seroquel as early as possible in the late evening is better, like 45-60 minutes from when you actually want to go to sleep at least, which pushes the half life back so you're not as groggy in the morning. You'll still be somewhat groggy, though.

I don't really like going to sleep on it but I have to take it at the moment -- its an odd sensation omce it starts working, you can't swallow very well, at least in my experience and you had better be in bed because it causes low blood pressure and one can feel faint.


I realize that's not a good outlook on the medication but besides Zyprexa its low on the totem pole of aggressiveness of neuroleptics except for Clozaril which one really doesn't want to go there unless absolutely necessary. Zyprexa would be a perfect drug for me if it didn't cause pseudoparkinsonism and didn't carry nearly the massive weight issue that Seroquel doesn't do as much.

-- tidings

Jay

 

Re: Seroquel Hangover- anyone else taking high dos

Posted by Lindenblüte on October 17, 2006, at 15:32:50

In reply to Re: Seroquel Hangover- anyone else taking high dos, posted by yxibow on October 17, 2006, at 2:09:15

> > Hi All,
> > in the last 10 days I have gradually increased my seroquel dose from 50 to 300 mg.
> >
> > It's SOOOO hard to peel my eyelids open in the am. I take provigil 200mg as soon as I get up, but I still feel like I have an oatmeal brain. Kind of like a hangover without the nausea.
> >
> > Pdoc said it might take a week OR SO to get over this. I never had a problem with daytime fatigue on 50mg of seroquel.
> >
> > Anyone with any experiences on these doses of seroquel?
> >
> > P.S. taking it for intrusive thoughts and flashbacks and nightmares, and for antidepressant augmentation and mood stabilization.
>
>
> Whew.. I've taken it up to 1200mg. I take it at 800mg currently for a non psychotic complex disorder, if that is any comparison of a high dose.

Okay- yes, pdoc told me that many people take up to 800mg. That's why I'm asking the board :) Thanks for responding.

> I once accidentally mistook it for another medication and I had a social meeting with someone , I was on 1600mg basically of it, I felt like a dork but managed to get home.


haha that sounds like the time when I accidentally took 200mg provigil at bedtime and wondered why I was dancing in bed all night long.
>
> Seroquel is the most sedating of all antipsychotics, including non atypicals. But I take it because it has the least EPS which I am sensitive to and the lowest risk of TD. I would never take neuroleptics but for this rare disorder I'm fighting.
>

I'm sorry you're fighting a rare disorder. That sounds really difficult. I definitely appreciate the low risk of TD from . My uncle had schizophrenia and developed the full-blown TD in the early 80's (well, he died before he became completley catatonic). Grandmother had Parkinson's
> But back to business.. yes, over time you get used to the fatigue, but from what I've learned, taking the Seroquel as early as possible in the late evening is better, like 45-60 minutes from when you actually want to go to sleep at least, which pushes the half life back so you're not as groggy in the morning. You'll still be somewhat groggy, though.
>
> I don't really like going to sleep on it but I have to take it at the moment -- its an odd sensation omce it starts working, you can't swallow very well, at least in my experience and you had better be in bed because it causes low blood pressure and one can feel faint.
>
>
> I realize that's not a good outlook on the medication but besides Zyprexa its low on the totem pole of aggressiveness of neuroleptics except for Clozaril which one really doesn't want to go there unless absolutely necessary. Zyprexa would be a perfect drug for me if it didn't cause pseudoparkinsonism and didn't carry nearly the massive weight issue that Seroquel doesn't do as much.

I'm okay, except for getting up in the am. today it took 1 hour to get out of bed. Once I was up- I was up. coffee and provigil save the day.


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