Psycho-Babble Medication Thread 579259

Shown: posts 1 to 12 of 12. This is the beginning of the thread.

 

Nardil poop out

Posted by Nardil on November 16, 2005, at 7:59:44

I have suffered from unipolar depression for the past 40 years. I have tried most antidepressant families and found them to be ineffective. ECT was also ineffective. Two and a half years ago, I finally started Nardil at 30 mg per day. It was a wonder drug. I am now at 90 mg per day, the highest dose my psychopharmacologist is comfortable with.

I am starting to get breakthrough depression on the order of two or three times a week. I will be discussing augmentation strategies with my psychopharmacologist in a few weeks, but I know his preference is lithium. Lithium was a disaster for me a few years ago as an augmentation agent, and I do not want to try it again. Does anyone have experience with other augmentation agents and Nardil? My time is running out. Thanks.

 

Re: Nardil poop out » Nardil

Posted by gardenergirl on November 16, 2005, at 8:44:25

In reply to Nardil poop out, posted by Nardil on November 16, 2005, at 7:59:44

I'm using Lamictal with Nardil with pretty good success.

75 mg Lamictal
60 mg Nardil

gg

 

Re: Nardil poop out » Nardil

Posted by tecknohed on November 16, 2005, at 9:16:48

In reply to Nardil poop out, posted by Nardil on November 16, 2005, at 7:59:44

Nardil is great, isn't it!? Pitty about its poopout. Unfortunitely this is far too common. Though it can certainly be augmented. Like gardenergirl, I too am considering adding Lamictal to Nardil. Seems like a well trodden path.

Currently I've been using Idebenone which has definitely enhance Nardil for me. Sold in the US as a health supplement, its actually a synthetic analoque of the antioxidant coQ10. Its cheap too, if you order it in bulk. I find it has a pronounced Serotonin effect so care should be taken if you do consider it.

I also take Provigil (modafinil) with Nardil. It has its own unique positive effect but I cann't say whether or not it actually augments the Nardil .

Don't know much about lithium I'm affraid, only that my pdoc said I'm better off without it.

teck

 

Re: Nardil poop out

Posted by blackcat23 on November 16, 2005, at 15:33:58

In reply to Re: Nardil poop out » Nardil, posted by tecknohed on November 16, 2005, at 9:16:48

In what way does Lamictal augment the Nardil?
I ask because I'm tapering off Lamictal now that Parnate is working for me.

 

Re: Nardil poop out » blackcat23

Posted by tecknohed on November 16, 2005, at 17:19:30

In reply to Re: Nardil poop out, posted by blackcat23 on November 16, 2005, at 15:33:58

> In what way does Lamictal augment the Nardil?
> I ask because I'm tapering off Lamictal now that Parnate is working for me.

Hi

I dont know much at all about the pharmacology of Lamictal. I guess it works similar to how other mood stabilizers appear to ehance antidepressants in unipolar depression. Whilst for bipolar people they have more of a stabilizing effect. Thats just my guess.

I am curious as to why you are tapering off Lamictal if it has helped you get better? I mean, even though you've been better since starting Parnate, you were still on a reasonable dose of Lamictal right? How do you know Lamictal didn't play its own part in your responce to the Parnate?

Regards,
teck

 

Re: Nardil poop out

Posted by willyee on November 16, 2005, at 18:04:52

In reply to Re: Nardil poop out, posted by blackcat23 on November 16, 2005, at 15:33:58

Many drugs are used to what you call "poentiate" another.So where as a certain drug might not be taken for ITS own specific benifit its taken caused its shown on occasion to jump start,kick,nudge or whatever other term ud like to use another med.

Some very common ones,esepcialy with both MAOIS are ..........

Pindolol

Lithium

Certain Benzos

Certain Anti-psychotics

Certain stimulants......i.e Ritalin/dexadrine/modfanil

Now some meds are prescribed along a AD cause they are needed,such as a benzo,simply to control anxiety.

This can be different than augmenting,for instance i do not believe im adhd,i never took ritalin as a child,i cant tolerate it now alone,HOwever when i added it to parnate i was finaly able to get some response back,which is what i have now.

Many people find lamictal to potentiate meds,personaly i found it halted my parnate and made me feel much worse,this is why its so tricky messing around with all these god awful drugs.

 

Re: Nardil poop out

Posted by Phillipa on November 16, 2005, at 23:38:35

In reply to Re: Nardil poop out, posted by willyee on November 16, 2005, at 18:04:52

If you try lamictal go slow and watch for the rash. Fondly, Phillipa

 

Re: Nardil poop out

Posted by Nardil on November 17, 2005, at 15:17:41

In reply to Nardil poop out, posted by Nardil on November 16, 2005, at 7:59:44

Thanks all. Will try lamictal.

 

Re: Nardil poop out » tecknohed

Posted by blackcat23 on November 17, 2005, at 19:10:25

In reply to Re: Nardil poop out » blackcat23, posted by tecknohed on November 16, 2005, at 17:19:30

I posted about this a few days ago-- (subject "Quitting Lamictal--Parnate is working")

I can't be sure that the Lamictal isn't associated with the positive effects of Parnate, but I guess I'll find out. The reasoning was that since I've been taking Lamictal consistently and have continued to get depressed, it hasn't been helping.

There's more about it in my other post. All my best...

 

Re: Nardil poop out

Posted by sdb on November 19, 2005, at 15:25:34

In reply to Re: Nardil poop out » tecknohed, posted by blackcat23 on November 17, 2005, at 19:10:25

Maybe very little bupropion would be a idea to counteract tiredness or no good efficacy against depression of nardil?

 

Re: Nardil poop out » Nardil

Posted by ace on November 21, 2005, at 23:56:02

In reply to Nardil poop out, posted by Nardil on November 16, 2005, at 7:59:44

> I have suffered from unipolar depression for the past 40 years. I have tried most antidepressant families and found them to be ineffective. ECT was also ineffective. Two and a half years ago, I finally started Nardil at 30 mg per day. It was a wonder drug. I am now at 90 mg per day, the highest dose my psychopharmacologist is comfortable with.
>
> I am starting to get breakthrough depression on the order of two or three times a week. I will be discussing augmentation strategies with my psychopharmacologist in a few weeks, but I know his preference is lithium. Lithium was a disaster for me a few years ago as an augmentation agent, and I do not want to try it again. Does anyone have experience with other augmentation agents and Nardil? My time is running out. Thanks.
>

Yes....

Try L-Trytophan + Lithium + Nardil
Low dose anti-psychotic (Zyprexa 2.5mg for example)
Carbamazepine
Remeron (this IS safe)
Clonidine
Topamax (worth a try)
Tramadol
Reboxetine


many more...don't give in!!!!!!!!

Ace

 

Re: Nardil poop out

Posted by jch on October 14, 2011, at 13:59:22

In reply to Nardil poop out, posted by Nardil on November 16, 2005, at 7:59:44

My solution to Nardil poop out, possibly due to change in shell, 354mgs of Aplenzin w/ 45 mgs of Nardil.

Two weeks in, 172mgs first week, feels like the old Marplan which was the best for me.

Will report if anything changes.


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